Nicorandil Market Size, Share & Trends Analysis Distribution by Dosage Form (Oral Solutions, Tablets, Injectables, and Extended-Release Formulations), Therapeutic Application (Hypertension, Ischemic Heart Disease, Heart Failure, and Chronic Stable Angina), Patient Demographics, End User, Distribution Channel and Segment Forecasts, 2025-2034

Nicorandil Market is estimated to grow with a CAGR of 8.5% during the forecast period of 2025-2034.

Nicorandil is a dual-action vasodilator and the only clinically approved potassium-channel activator with nitrate-like properties. It treats chronic stable angina pectoris by opening ATP-sensitive potassium channels in vascular smooth muscle and donating nitric oxide, resulting in both arterial and venous dilation.

This mechanism rapidly increases coronary blood flow, boosts oxygen delivery to the heart, and reduces cardiac preload and afterload, effectively relieving and preventing angina symptoms. Administered orally (typically 10–20 mg twice daily), it is indicated when beta-blockers or calcium-channel blockers are contraindicated or insufficient, and remains a standard therapy in Europe, Japan, and many Asia-Pacific and Middle East markets.

The Nicorandil market is growing steadily due to the rising number of people with heart disease worldwide. Aging populations, more sedentary lifestyles, and increasing rates of diabetes, high blood pressure, and obesity are driving up angina cases. The growing elderly population – who are most at risk – is a major factor boosting demand. Better healthcare systems in developing countries, higher patient awareness, and increased spending on cardiovascular medicines also support market growth.

Side effects such as headaches, dizziness, and rare but serious mouth or gut ulcers can limit patient acceptance. Newer angina treatments and generic competition are additional challenges. However, ongoing research into improved formulations (e.g., sustained-release versions) and expanding use in emerging markets offer strong growth potential. As heart disease remains a majorcause of death globally, Nicorandil continues to play an important role in affordable, effective angina management.

Competitive Landscape

Some of the Key Players in Nicorandil Market:

•    Nanjing Luomeimei Biotechnology Co. LTD
•    Merck
•    Shanghai Myrell Chemical Technology Co. LTD
•    Shanghai Yuanye Bio-Technology Co. Ltd
•    J&K Scientific
•    Shenzhen Feisi Biological Technology Co. LTD
•    Yunnan Xili Biotechnology Co. LTD
•    Shanghai Aladdin Biochemical Technology Co. LTD
•    Nanjing Shenglide Biotechnology Co. LTD
•    Biorbyt
•    Biosynth Carbosynth
•    ApexBio Technology
•    Santa Cruz BiotechnologyInc.
•    Combi-Blocks Inc
•    AdooQ BioScience
•    Wuhan Belka Biomedicine
•    Alfa Chemistry
•    Toronto Research Chemicals Inc
•    Apollo Scientific Ltd
•    3B Scientific
•    Carbone Scientific
•    Cayman Chemical
•    TCI
•    Targetmol
•    QCC
•    A&A Life Science Inc

Market Segmentation:

The nicorandil market is segmented by dosage form, therapeutic application, patient demographics, end user, and distribution channel. By dosage form, the market is segmented into oral solutions, tablets, injectables, and extended-release formulations. As per the therapeutic application, the market is segmented into hypertension, ischemic heart disease, heart failure, and chronic stable angina.

By patient demographics, the market is segmented into pediatric patients, young adults (18-44 years), middle-aged (45-64 years), and aged (65+ years). By end user, the market is segmented into healthcare professionals (doctors, cardiologists), pharmacists, patients, and healthcare institutions. The distribution channel segment comprises into hospitals and clinics, retail pharmacies, specialty pharmacies, and online pharmacies.

By Dosage Form, the Oral Solutions Segment is Expected to Drive the Nicorandil Market 

The oral solutions category held the largest share in the Nicorandil market in 2024. Oral dose forms are the most widely recognized and usually recommended manner of delivering Nicorandil, with tablets being the prevalent type. This simplicity and patient compliance elevate the oral route's attractiveness, allowing for stable therapeutic levels without the requirement for expert administration, making it ideal for long-term maintenance. In order to improve absorption and maintain therapeutic benefits over time, oral versions are frequently made using a controlled-release mechanism.

Ischemic Heart Disease Segment by Therapeutic Application is Growing at the Highest Rate in the Nicorandil Market

In 2024, the Ischemic Heart Disease category dominated the Nicorandil market. Ischemic heart disease, which includes a variety of disorders marked by decreased blood flow to the heart muscle, makes up the greatest portion of the therapeutic application category. Due to the increased occurence of ischemic heart diseases worldwide, which are caused by risk factors such as diabetes, hypertension, and lifestyle decisions, this category is leading.

According to the World Health Organization, ischemic heart disease accounts for 16% of all fatalities globally, making it the leading cause of mortality. The need for Nicorandil as a treatment option is anticipated to increase as medical professionals become more aware of the significance of efficient management techniques for ischemic heart disease.

Regionally, North America is leading the Nicorandil Market

North America commands the leading market share in the global nicorandil landscape, characterized by its sophisticated and high-capacity healthcare ecosystem. The region’s dominance is underpinned by a significant patient population diagnosed with chronic stable angina and other ischemic heart conditions, supported by widespread diagnostic capabilities and a treatment culture that integrates both established and newer therapeutic options.

A mature pharmaceutical supply chain, combined with favorable reimbursement structures for cardiovascular medications, ensures consistent product availability and patient access. This established commercial footprint is reinforced by ongoing cardiology research and clinical education that maintains physician awareness of nicorandil’s role in specific treatment algorithms, particularly for patients with refractory symptoms.

The Asia Pacific region is positioned for the most rapid expansion within the nicorandil market, representing the highest projected growth rate. This acceleration is driven by powerful demographic and systemic trends, including a sharply rising prevalence of hypertension, diabetes, and coronary artery disease across its vast and aging populations. Growth is further catalyzed by substantial governmental and private investment in healthcare infrastructure, which is improving diagnosis and treatment rates in both urban and emerging rural markets.

The region also benefits from the drug's established history and deep clinical familiarity in key markets like Japan and South Korea, while growth engines such as China and India contribute through scaling domestic pharmaceutical production, increasing physician adoption, and expanding insurance coverage for chronic disease management.

Nicorandil Market Report Scope:

Segmentation of Nicorandil Market -

Nicorandil Market by Dosage Form-

•    Oral Solutions
•    Tablets
•    Injectables
•    Extended-Release Formulations

Nicorandil Market by Therapeutic Application -

•    Hypertension
•    Ischemic Heart Disease
•    Heart Failure
•    Chronic Stable Angina

Nicorandil Market by Patient Demographics-

•    Pediatric Patients
•    Young Adults (18-44 Years)
•    Middle-Aged (45-64 Years)
•    Aged (65+ Years)

Nicorandil Market by End User-

•    Healthcare Professionals

o    Doctors
o    Cardiologists

•    Pharmacists
•    Patients
•    Healthcare Institutions

Nicorandil Market by Distribution Channel-

•    Hospitals and Clinics
•    Retail Pharmacies
•    Specialty Pharmacies
•    Online Pharmacies

Nicorandil Market by Region-

North America-

•    The US
•    Canada

Europe-

•    Germany 
•    The UK
•    France
•    Italy 
•    Spain 
•    Rest of Europe

Asia-Pacific-

•    China
•    Japan 
•    India
•    South Korea
•    Southeast Asia
•    Rest of Asia Pacific

Latin America-

•    Brazil
•    Argentina
•    Mexico
•    Rest of Latin America

Middle East & Africa-

•    GCC Countries
•    South Africa 
•    Rest of the Middle East and Africa