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mRNA Synthesis Raw Materials Market

Global mRNA Synthesis Raw Materials Market Size, Share & Trends Analysis Report By Type(Capping Enzymes, DNA template, Nucleotides, Polymerase), By Application(Therapeutics Production, Vaccine Production, Drug Discovery), By End_User, By Region, And Segment Forecasts, 2024-2031

Report ID : 1497 | Published : 2024-02-20 | Pages: 184 | Format: PDF/EXCEL

The mRNA Synthesis Raw Materials Market Size is valued at USD 3.47 Billion in 2023 and is predicted to reach USD 14.91 Billion by the year 2031 at a 20.48% CAGR during the forecast period for 2024-2031.

Key Industry Insights & Findings from the Report:

  • Leading pharmaceutical companies new product introductions that improve service quality, rising service standards, and increased facility personalization are driving the RNA synthesis raw material market.
  • A greater understanding of the significance of early detection and treatment of chronic diseases among the general public and healthcare professionals is anticipated to fuel market growth.
  • North America dominated the market and accounted for a revenue share of global revenue in 2023.
  • Expanding mRNA synthesis of raw materials is hindered by a lack of flexible, durable, and cost-effective manufacturing procedures.

 mrna

mRNA is a superior platform for creating preventative or therapeutic vaccines for various chronic and infectious diseases because it is adaptable and flexible. mRNA vaccines are more efficacious, have better immunogenicity, and cost less to produce than traditional treatments. For the projection period, mRNA synthesis and production services are anticipated to have rapid market expansion due to ongoing breakthroughs and advancements. Due to the key market players' goal of providing superior quality and efficacy products, there is an increasing demand for high-quality raw materials for efficient mRNA synthesis. This is essential for developing safe and effective pharmaceutical goods, vaccines, and medications. Key competitors' alliances, acquisitions, and partnerships to increase the supply of raw materials also drive the industry. The market is expanding due to new pharmaceutical companies' inventions, improved medical technology, and greater customization of facilities and services with higher quality and effectiveness.

Competitive Landscape

Some major key players in the mRNA synthesis raw materials market :

  • Hoffmann-La Roche Ltd.
  • Jena Bioscience GmbH
  • Merck KGaA
  • Yeasen Biotechnology (Shanghai) Co., Ltd.
  • BOC Sciences
  • Thermo Fisher Scientific, Inc.
  • Maravai LifeSciences
  • New England Biolabs
  • Creative Biogene
  • HONGENE

Market Segmentation:

The mRNA synthesis raw materials market is segmented on the try, applications and end-use. Based on the product type, the mRNA synthesis raw materials market is segmented into capping enzymes, DNA templates, nucleotides, and polymerase. The mRNA synthesis raw materials market is segmented based on applications into therapeutics production, vaccine production, and drug discovery. Based on end-use, the mRNA synthesis raw materials market is segmented into biotechnology companies, pharmaceutical companies, research and academic institutes, and others.

Based On Type, The Nucleotide Segment Is A Significant Contributor To The mRNA Synthesis Raw Materials Market.

The market's leading segment is nucleotide due to the penetration of nucleotides in applications such as nutraceuticals, pharmaceuticals, food and beverage additives, diagnostics research, and others. The market for nucleotides is experiencing explosive expansion thanks to the usage of nucleotides in boosting immunity. A strong network of raw materials vendors and suppliers is required for production to run smoothly. As a result, the participants network with suppliers of raw materials and merchandise.

The Research And Academic Institutes Segment Witnessed Growth At A Rapid Rate.

Research and academic institutes grabbed the highest revenue share, and it is anticipated that they will continue to hold that position during the expected time owing to the wide acceptance of mRNA synthesis in academia and research. The sub-rapid segment's expansion is attributable to funding from the government, support from other organizations, and collaborations between various groups from different locations. Throughout the forecast period, such variables could generate significant potential for the sub-segment.

The North American mRNA Synthesis Raw Materials Market Holds A Significant Regional Revenue Share.

The North American mRNA synthesis raw materials market is expected to register the highest market share in revenue soon. Due to the presence of significant mRNA vaccine production facilities, the United States is expected to maintain its leadership in the industry. Leading firms with well-established production facilities for mRNA vaccines and treatments, such as Pfizer and Moderna, have facilities in the United States, which will help this area continue its dominance during the projection period. In addition, Asia Pacific is projected to increase in the global mRNA synthesis raw materials market because of increased spending on research and development, a rise in the prevalence of chronic diseases, and the quick uptake of cutting-edge technologies.

Recent Developments

  • In Nov 2021, BOC RNA declared the growth of its oligo synthesis services with the intention of catering to a more diverse clientele within the biomedical sector.    In addition to natural DNA, siRNA, mRNA, and DNA/RNA oligos, BOC RNA offered a variety of oligonucleotides and derivative synthesis services, including non-natural and more stable oligonucleotides (cGMP grade and non-cGMP grade).
  • In Sept 2022, Thermo Fisher Scientific introduced scalable mRNA production solutions utilizing customized Dynabeads. Utilizing Streptavidin for In Vitro Transcription and Carboxylic Acid for RNA Purification by Dynabeads enabled scalable, GMP-grade mRNA synthesis and purification for vaccine research and production. The Thermo ScientificTM TheraPureTM GMP portfolio of nucleotides and enzymes facilitated the workflow by providing solutions suitable for their intended use. It assisted mRNA companies in advancing more rapidly from development to commercialization.

mRNA Synthesis Raw Materials Market Report Scope

Report Attribute

Specifications

Market Size Value In 2023

USD 3.47 Billion

Revenue Forecast In 2031

USD 14.91 Billion

Growth Rate CAGR

CAGR of 20.48 % from 2024 to 2031

Quantitative Units

Representation of revenue in US$ Million and CAGR from 2024 to 2031

Historic Year

2019 to 2023

Forecast Year

2024-2031

Report Coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments Covered

By Type, By Application, By End-User

Regional Scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country Scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia

Competitive Landscape

F. Hoffmann-La Roche Ltd., Jena Bioscience GmbH, Merck KGaA, Yeasen Biotechnology (Shanghai) Co., Ltd., BOC Sciences, Thermo Fisher Scientific, Inc., Maravai LifeSciences, New England Biolabs, Creative Biogene, HONGENE

Customization Scope

Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape.

Pricing And Available Payment Methods

Explore pricing alternatives that are customized to your particular study requirements.

 

 

 

Chapter 1. Methodology and Scope

1.1. Research Methodology

1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global mRNA Synthesis Raw Materials Market Snapshot

Chapter 4. Global mRNA Synthesis Raw Materials Market Variables, Trends & Scope

4.1. Market Segmentation & Scope

4.2. Drivers

4.3. Challenges

4.4. Trends

4.5. Investment and Funding Analysis

4.6. Industry Analysis – Porter’s Five Forces Analysis

4.7. Competitive Landscape & Market Share Analysis

4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: by Product Type Estimates & Trend Analysis

5.1. by Product Type & Market Share, 2019 & 2031

5.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2023 to 2031 for the following by Product Type:

5.2.1. Capping Enzymes

5.2.2. DNA template

5.2.3. Nucleotides

5.2.4. Polymerase

Chapter 6. Market Segmentation 2: by Application Estimates & Trend Analysis

6.1. by Application & Market Share, 2019 & 2031

6.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2023 to 2031 for the following by Application:

6.2.1. Therapeutics Production

6.2.2. Vaccine Production

6.2.3. Drug Discovery

Chapter 7. Market Segmentation 3: by End-user Estimates & Trend Analysis

7.1. by End-user & Market Share, 2019 & 2031

7.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2023 to 2031 for the following by End-user:

7.2.1. Biotechnology Companies

7.2.2. Pharmaceutical Companies

7.2.3. Research and Academic Institutes

7.2.4. Others

Chapter 8. mRNA Synthesis Raw Materials Market Segmentation 4: Regional Estimates & Trend Analysis

8.1. North America

8.1.1. North America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Product Type, 2024-2031

8.1.2. North America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031

8.1.3. North America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by End-user, 2024-2031

8.1.4. North America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.2. Europe

8.2.1. Europe MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Product Type, 2024-2031

8.2.2. Europe MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031

8.2.3. Europe MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by End-user, 2024-2031

8.2.4. Europe MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.3. Asia Pacific

8.3.1. Asia Pacific MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Product Type, 2024-2031

8.3.2. Asia Pacific MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031

8.3.3. Asia-Pacific MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by End-user, 2024-2031

8.3.4. Asia Pacific MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.4. Latin America

8.4.1. Latin America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Product Type, 2024-2031

8.4.2. Latin America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031

8.4.3. Latin America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by End-user, 2024-2031

8.4.4. Latin America MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.5. Middle East & Africa

8.5.1. Middle East & Africa MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Product Type, 2024-2031

8.5.2. Middle East & Africa MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031

8.5.3. Middle East & Africa MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by End-user, 2024-2031

8.5.4. Middle East & Africa MRNA Synthesis Raw Materials Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

Chapter 9. Competitive Landscape

9.1. Major Mergers and Acquisitions/Strategic Alliances

9.2. Company Profiles

9.2.1. F. Hoffmann-La Roche Ltd.

9.2.2. Jena Bioscience

9.2.3. Yeasen Biotechnology (Shanghai) Co., Ltd.

9.2.4. BOC Sciences

9.2.5. Thermo Fisher Scientific, Inc.

9.2.6. Maravai LifeSciences

9.2.7. New England Biolabs

9.2.8. Creative Biogene

9.2.9. Merck KGaA

9.2.10. HONGENE

9.2.11. Other Prominent Players

Segmentation of mRNA Synthesis Raw Materials Market-

By Type

  • Capping Enzymes,
  • DNA template
  • Nucleotides
  • Polymerase

mRNA Synthesis Raw Materials Market

By Application

  • Therapeutics Production,
  • Vaccine Production
  • Drug Discovery

By End-user

  • Biotechnology Companies
  • Pharmaceutical Companies
  • Research and Academic Institutes
  • Others

By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • South East Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

What is the mRNA Synthesis Raw Materials Market Growth?

F. Hoffmann-La Roche Ltd., Jena Bioscience GmbH, Merck KGaA, Yeasen Biotechnology (Shanghai) Co., Ltd., BOC Sciences, Thermo Fisher Scientific, Inc.,

The mRNA Synthesis Raw Materials Market Size is valued at USD 3.47 Billion in 2023 and is predicted to reach USD 14.91 Billion by the year 2031.

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