Global mRNA Extraction and Purification Market Size is valued at USD 1105.2 Million in 2024 and is predicted to reach USD 7561.2 Million by the year 2034 at a 21.6% CAGR during the forecast period for 2025-2034.
Purification and isolation or extraction processes are mandatory for all types of medical research. mRNA Purification and extraction are performed by using different kinds of methods. Many specialized methods are available for extracting mRNAs, such as solution-based and column-based protocols in which column-based techniques are widely used to isolate mRNA. One of the most effective and reliable methods of mRNA isolation is the magnetic separation method with oligo (dT) bound on the surface of paramagnetic beads.
The manual process has certainly advanced over time, with various commercial offerings, including complete kits containing most of the components required to isolate nucleic acid. Different reagents, including enzymes and buffers, are used for these processes. Enzymes and buffers containing chaotropic agents such as guanidinium isothiocyanate, sarcosyl, guanidinium chloride, sodium dodecyl sulphate (SDS), urea, phenol, or chloroform are used in extraction and purification processes. In research, mRNA provides critical information about which proteins are being translated and how much transcript is being produced by the cell. Synthetic mRNA production requires a purification step to get the final mRNA product out of the solution in which it was transcribed.
There is an exponential surge in COVID-19 diagnostic testing and vaccine and medication development in laboratories, hospitals, and other testing facilities worldwide. The life science industry is heavily investing in the healthcare industry, and this stimulates the research efforts of biopharmaceutical firms. In order to produce novel goods to fulfil the research needs of the pharmaceutical and biotechnology industries, makers of kits and instruments have also expanded their R&D spending. Omega Bio-tek announced the expansion of its facilities in December 2020 in response to a rise in demand for its DNA/RNA purification kits and automation support services.
RNA isolation & purification kits and automated devices are more expensive than conventional procedures, which may hinder market expansion. This expensive equipment is unaffordable to institutes and firms with lesser R&D resources.
The life science research market in North America and Europe is focused on the usage of RNA purification products, resulting in significant investments, financing, and partnerships for market growth over the projection period.
Global mRNA Extraction and Purification Market is segmented by Product Type, Method Type, applications, and End-user. By means of product type segment, it includes Kits, Reagents and Instruments. The Methode Type segment consists of Chromatography ( Affinity ( OligodT Chromatography Resins, Others), Ion Exchange, Hydrophobic Interaction, Others (Multimodal, Reverse Phase, etc.)), Oligo Deoxythymidine (dT) Magnetic Particles, Lithium Chloride Precipitation, whereas by application market is divided into infectious disease vaccines, other vaccines, therapeutics & others. At last end-user segment covers Academics and Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, and Other End Users (Hospitals, etc.).
| Report Attribute | Specifications |
| Growth rate CAGR | CAGR of 21.6 % from 2025 to 2034 |
| Quantitative units | Representation of revenue in US$ Million and CAGR from 2025 to 2034 |
| Historic Year | 2021 to 2024 |
| Forecast Year | 2025-2034 |
| Report coverage | The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
| Segments covered | By Product Type, Method Type, By Application, By Ene-User |
| Regional scope | North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
| Country scope | U.S.; Canada; Germany; China; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; Japan; India; South East Asia; South Korea |
| Competitive Landscape | Qiagen, Thermo Fisher Scientific, Promega Corporation, Agilent Technologies, Inc, Merck Kgaa, Miltenyi Biotec , Biobasic Inc, Takara Bio, Inc, New England Biolabs, Omega Bio-Tek, Inc, Norgen Biotek, Zymo Research, F. Hoffmann-La Roche Ag, Genaxxon Bioscience Gmbh, Biovision, Analytik Jena Ag, Bio-Rad Laboratories, Inc, AccuBioMed, NEBNext Poly(A) mRNA Magnetic Isolation Module, Arraystar, Inc, Fisher BioReagents, CD Bioparticles, United States Biological, Vdo Biotech, Bulldog Bio Inc |
| Customization scope | Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape. |
| Pricing and available payment methods | Explore pricing alternatives that are customized to your particular study requirements. |
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global MRNA Synthesis Raw Materials Market Snapshot
Chapter 4. Global MRNA Synthesis Raw Materials Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis of Metaverse Industry
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. COVID-19 Impact on Metaverse Industry
Chapter 5. Market Segmentation 1: By Product Type Estimates & Trend Analysis
5.1. By Product Type & Market Share, 2034-2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Product Type:
5.2.1. Kits
5.2.2. Reagents
5.2.3. Instruments
Chapter 6. Market Segmentation 2: By Method Type Estimates & Trend Analysis
6.1. By Method Type & Market Share, 2024-2034
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Method Type:
6.2.1. Polymerase Chain Reaction (PCR)
6.2.2. Chromatography
6.2.2.1. Affinity
6.2.2.2. OligodT Chromatography Resins
6.2.2.3. Others
6.2.2.4. Ion Exchange
6.2.2.5. Hydrophobic Interaction
6.2.2.6. Others (Multimodal, Reverse Phase, etc.)
6.2.3. Oligo Deoxythymidine (dT) Magnetic Particles
6.2.4. Lithium Chloride Precipitation
Chapter 7. Market Segmentation 3: By Application Estimates & Trend Analysis
7.1. By Application & Market Share, 2024-2034
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Application:
7.2.1.1. Vaccine Production
7.2.1.2. Protein Replacement Therapies
7.2.1.3. Cancer Immunotherapies
Chapter 8. Market Segmentation 5: By End-User Estimates & Trend Analysis
8.1. By End-User & Market Share, 2024-2034
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By End-User:
8.2.1.1. Hospitals and Clinics
8.2.1.2. Biotechnology & Pharmaceutical Companies
8.2.1.3. Contract Research Organizations
8.2.1.4. Academic & Research Institutions
Chapter 9. MRNA Synthesis Raw Materials Market Segmentation 4: Regional Estimates & Trend Analysis
9.1. North America
9.1.1. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Product Type, 2021-2034
9.1.2. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.1.3. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.1.4. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.1.5. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.2. Europe
9.2.1. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2021-2034
9.2.2. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.2.3. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.2.4. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.2.5. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, 2021-2034
9.3. Asia Pacific
9.3.1. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2021-2034
9.3.2. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.3.3. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.3.4. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.3.5. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, 2021-2034
9.4. Latin America
9.4.1. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2021-2034
9.4.2. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.4.3. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.4.4. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.4.5. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, (US$ Million) 2021-2034
9.5. Middle East & Africa
9.5.1. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, (US$ Million)
9.5.2. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.5.3. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.5.4. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.5.5. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, (US$ Million) 2021-2034
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. Qiagen
10.2.2. Thermo Fisher Scientific
10.2.3. Promega Corporation
10.2.4. Agilent Technologies, Inc
10.2.5. Merck Kgaa
10.2.6. Miltenyi Biotec
10.2.7. Biobasic Inc
10.2.8. Takara Bio, Inc
10.2.9. New England Biolabs
10.2.10. Omega Bio-Tek, Inc
10.2.11. Norgen Biotek
10.2.12. Codex DNA, Inc.
10.2.13. Sartorius Stedim Biotech GmbH
10.2.14. Zymo Research
10.2.15. F. Hoffmann-La Roche Ag
10.2.16. Genaxxon Bioscience Gmbh
10.2.17. Biovision
10.2.18. Analytik Jena Ag
10.2.19. Bio-Rad Laboratories, Inc
10.2.20. AccuBioMed
10.2.21. NEBNext Poly(A) mRNA Magnetic Isolation Module
10.2.22. Arraystar, Inc
10.2.23. Fisher BioReagents
10.2.24. CD Bioparticles
10.2.25. United States Biological
10.2.26. Vdo Biotech
10.2.27. Bulldog Bio Inc
10.2.28. Other Prominent Players
Global mRNA Extraction And Purification Market By Product Type
Global mRNA Extraction And Purification Market By Method Type
Global mRNA Extraction And Purification Market By Application
Global mRNA Extraction And Purification Market By End-Users,
Global mRNA Extraction And Purification Market By Region,
North America mRNA Extraction And Purification Market, by Country
Europe mRNA Extraction And Purification Market, by Country
Asia Pacific mRNA Extraction And Purification Market, by Country
Latin America mRNA Extraction And Purification Market, by Country
Middle East & Africa mRNA Extraction And Purification Market, by Country