Global mRNA Extraction and Purification Market Size is valued at USD 1105.2 Million in 2024 and is predicted to reach USD 7561.2 Million by the year 2034 at a 21.6% CAGR during the forecast period for 2025-2034.
Purification and isolation or extraction processes are mandatory for all types of medical research. mRNA Purification and extraction are performed by using different kinds of methods. Many specialized methods are available for extracting mRNAs, such as solution-based and column-based protocols in which column-based techniques are widely used to isolate mRNA. One of the most effective and reliable methods of mRNA isolation is the magnetic separation method with oligo (dT) bound on the surface of paramagnetic beads.
The manual process has certainly advanced over time, with various commercial offerings, including complete kits containing most of the components required to isolate nucleic acid. Different reagents, including enzymes and buffers, are used for these processes. Enzymes and buffers containing chaotropic agents such as guanidinium isothiocyanate, sarcosyl, guanidinium chloride, sodium dodecyl sulphate (SDS), urea, phenol, or chloroform are used in extraction and purification processes. In research, mRNA provides critical information about which proteins are being translated and how much transcript is being produced by the cell. Synthetic mRNA production requires a purification step to get the final mRNA product out of the solution in which it was transcribed.
There is an exponential surge in COVID-19 diagnostic testing and vaccine and medication development in laboratories, hospitals, and other testing facilities worldwide. The life science industry is heavily investing in the healthcare industry, and this stimulates the research efforts of biopharmaceutical firms. In order to produce novel goods to fulfil the research needs of the pharmaceutical and biotechnology industries, makers of kits and instruments have also expanded their R&D spending. Omega Bio-tek announced the expansion of its facilities in December 2020 in response to a rise in demand for its DNA/RNA purification kits and automation support services.
RNA isolation & purification kits and automated devices are more expensive than conventional procedures, which may hinder market expansion. This expensive equipment is unaffordable to institutes and firms with lesser R&D resources.
The life science research market in North America and Europe is focused on the usage of RNA purification products, resulting in significant investments, financing, and partnerships for market growth over the projection period.
Global mRNA Extraction and Purification Market is segmented by Product Type, Method Type, applications, and End-user. By means of product type segment, it includes Kits, Reagents and Instruments. The Methode Type segment consists of Chromatography ( Affinity ( OligodT Chromatography Resins, Others), Ion Exchange, Hydrophobic Interaction, Others (Multimodal, Reverse Phase, etc.)), Oligo Deoxythymidine (dT) Magnetic Particles, Lithium Chloride Precipitation, whereas by application market is divided into infectious disease vaccines, other vaccines, therapeutics & others. At last end-user segment covers Academics and Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, and Other End Users (Hospitals, etc.).
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Report Attribute |
Specifications |
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Growth rate CAGR |
CAGR of 21.6 % from 2025 to 2034 |
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Quantitative units |
Representation of revenue in US$ Million and CAGR from 2025 to 2034 |
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Historic Year |
2021 to 2024 |
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Forecast Year |
2025-2034 |
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Report coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
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Segments covered |
By Product Type, Method Type, By Application, By Ene-User |
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Regional scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
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Country scope |
U.S.; Canada; Germany; China; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; Japan; India; South East Asia; South Korea |
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Competitive Landscape |
Qiagen, Thermo Fisher Scientific, Promega Corporation, Agilent Technologies, Inc, Merck Kgaa, Miltenyi Biotec , Biobasic Inc, Takara Bio, Inc, New England Biolabs, Omega Bio-Tek, Inc, Norgen Biotek, Zymo Research, F. Hoffmann-La Roche Ag, Genaxxon Bioscience Gmbh, Biovision, Analytik Jena Ag, Bio-Rad Laboratories, Inc, AccuBioMed, NEBNext Poly(A) mRNA Magnetic Isolation Module, Arraystar, Inc, Fisher BioReagents, CD Bioparticles, United States Biological, Vdo Biotech, Bulldog Bio Inc |
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Customization scope |
Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape. |
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Pricing and available payment methods |
Explore pricing alternatives that are customized to your particular study requirements. |
Global mRNA Extraction And Purification Market By Product Type
Global mRNA Extraction And Purification Market By Method Type
Global mRNA Extraction And Purification Market By Application
Global mRNA Extraction And Purification Market By End-Users,
Global mRNA Extraction And Purification Market By Region,
North America mRNA Extraction And Purification Market, by Country
Europe mRNA Extraction And Purification Market, by Country
Asia Pacific mRNA Extraction And Purification Market, by Country
Latin America mRNA Extraction And Purification Market, by Country
Middle East & Africa mRNA Extraction And Purification Market, by Country
InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.
Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.
Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.
Secondary research
The secondary research sources that are typically mentioned to include, but are not limited to:
The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista
Primary Research:
Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies
The contributors who typically take part in such a course include, but are not limited to:
Data Modeling and Analysis:
In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.
The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.
To know more about the research methodology used for this study, kindly contact us/click here.
