Global mRNA Synthesis and Manufacturing Services Market

Report ID : 1185 | Published : 2021-09-02 | Pages: 165 | Format: PDF/EXCEL

The global mRNA synthesis and manufacturing services market size valued at US$ 2,723.5 Million in 2020 and it is expected to reach US$ 11,395.4 Million in 2030, recording a promising CAGR of 14.8% during the period of 2021-2030. By region, North America dominates the mRNA synthesis and manufacturing services market with share of 50.7% of total global market

Due to its versatile and flexible nature, mRNA is an excellent platform for developing prophylactic or therapeutic vaccines against various chronic and infectious diseases. Compared to conventional medicines, mRNA vaccines have higher effectiveness, improved immunogenicity, and required less manufacturing cost. The constant innovations and improvements in mRNA synthesis and manufacturing services are expected to propel the market growth of mRNA synthesis and manufacturing services over the forecast period. During the current Covid-2019 pandemic, many companies have chosen mRNA vaccine technology to combat coronavirus. For instance, in November 2020, Pfizer Inc. and BioNTech SE announced their mRNA-based vaccine candidate, BNT162b2, against SARS-CoV-2 had demonstrated evidence of efficacy against COVID-19 in participants without prior evidence of SARS-CoV-2 infection.

The increasing need for gene therapies, growing chronic and infectious diseases, and the rising number of clinical trials for cancer therapies and infectious diseases are likely to evolve the mRNA synthesis and manufacturing services market at a considerable rate in the next few years. Furthermore, advanced medical technologies, increasing customizable facilities, improving quality and efficacy services, and novel innovations by pharmaceutical companies enhance the market growth. However, the lack of flexible, sustainable, and cost-effective manufacturing processes hinders the growth of mRNA synthesis and manufacturing services.

Segmentation of mRNA synthesis and manufacturing services market includes Products, Applications, Scale of Operation, and Region. The market can be segmented into API and Drug Products based on Products. By Applications, the market is categorized into Infectious Disease Vaccines, Other Vaccines, Therapeutics and Others. Based on the Scale of Operation, the market is segmented into Research / Preclinical, Clinical, and Commercial. Regionally, the mRNA synthesis and manufacturing services market can be divided into North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa. North America, followed by Europe and the Asia Pacific, holds the maximum share of this market due to increased research and development expenditure, increased prevalence of infectious diseases, and the fast adoption of advanced technologies.

Some of the key players of the mRNA synthesis and manufacturing services market are Eurogentec, Aldevron, eTheRNA (Etherna Immunotherapies), biosynthesis, TriLink BioTechnologies, Biomay, Jena Biosciences, APExBIO, CELLSCRIPT, Thermo Fisher Scientific, New England Biolabs, CureVac, Moderna, BioNTech (Pfizer), Translate Bio, Ethris (AstraZeneca), Kernal Biologics, Silence Therapeutics, Tiba Biotechnology, In-Cell-Art, Anima Biotch, H3 Biomedicine Inc., Arcturus Therapeutics, eFFECTOR Therapeutics, Inc., Ionis Pharmaceuticals, Inc., Stemirna Therapeutics Co., Ltd., Skyhawk Therapeutics, Inc, RNAimmune (Sirnaomics), Ziphius Therapeutics NV, miRagen Therapeutics, Inc., Strand Therapeutics Inc., and other Prominent Players.

Chapter 1. Methodology and Scope

1.1. Research Methodology

1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global mRNA Synthesis and Manufacturing Services Market Snapshot

Chapter 4. Global mRNA Synthesis and Manufacturing Services Market Variables, Trends & Scope

4.1. Market Segmentation & Scope

4.2. Drivers

4.3. Challenges

4.4. Trends

4.5. Investment and Funding Analysis

4.6. Industry Analysis – Porter’s Five Forces Analysis

4.7. Competitive Landscape & Market Share Analysis

4.8. Impact of Covid-19 Analysis

4.9. Clinical Trial/Pipeline Analysis

Chapter 5. Market Segmentation 2: By Products Estimates & Trend Analysis

5.1. By Products & Market Share, 2020 & 2030

5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 for the following By Products:

5.2.1. API

5.2.2. Drug Products

Chapter 6. Market Segmentation 3: By Applications Estimates & Trend Analysis

6.1. By Applications & Market Share, 2020& 2030

6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 for the following By Applications:

6.2.1. Infectious Disease Vaccines

6.2.2. Other Vaccines

6.2.3. Therapeutics and Others 

Chapter 7. Market Segmentation 3: By Scale of Operation Estimates & Trend Analysis

7.1. By Scale of Operation & Market Share, 2020& 2030

7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 for the following By Scale of Operation:

7.2.1. Research / Preclinical

7.2.2. Clinical

7.2.3. Commercial

Chapter 8. mRNA Synthesis and Manufacturing Services Market Segmentation 4: Regional Estimates & Trend Analysis

8.1. North America

8.1.1. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Products, 2020-2030

8.1.2. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Applications, 2020-2030

8.1.3. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2020-2030

8.1.4. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by country, 2020-2030

8.2. Europe

8.2.1. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Products, 2020-2030

8.2.2. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Applications, 2020-2030

8.2.3. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2020-2030

8.2.4. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) by country, 2020-2030

8.3. Asia Pacific

8.3.1. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Products, 2020-2030

8.3.2. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Applications, 2020-2030

8.3.3. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2020-2030

8.3.4. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) by country, 2020-2030

8.4. Latin America

8.4.1. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Products, 2020-2030

8.4.2. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Applications, 2020-2030

8.4.3. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2020-2030

8.4.4. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) by country, (US$ Million) 2020-2030

8.5. Middle East & Africa

8.5.1. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Products, 2020-2030

8.5.2. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) By Applications, 2020-2030

8.5.3. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2020-2030

8.5.4. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) by country, 2020-2030

Chapter 9. Competitive Landscape

9.1. Major Mergers and Acquisitions/Strategic Alliances

9.2. Company Profiles

9.2.1. Eurogentec

9.2.2. Aldevron

9.2.3. eTheRNA (Etherna Immunotherapies)

9.2.4. bioSYNTHESIS

9.2.5. TriLink BioTechnologies

9.2.6. Biomay

9.2.7. Jena Biosciences

9.2.8. APExBIO

9.2.9. CELLSCRIPT

9.2.10. Thermo Fisher Scientific

9.2.11. New England Biolabs

9.2.12. Celonic AG

9.2.13. Corden Pharma GmbH

9.2.14. Lonza Group AG

9.2.15. Rentschler Biopharma

9.2.16. Laboratorios Farmacéuticos Rovi, S.A.

9.2.17. Samsung Biologics

9.2.18. CureVac

9.2.19. Moderna

9.2.20. BioNTech (Pfizer)

9.2.21. Translate Bio

9.2.22. Ethris (AstraZeneca)

9.2.23. Kernal Biologics

9.2.24. Silence Therapeutics

9.2.25. Tiba Biotechnology

9.2.26. In-Cell-Art

9.2.27. Anima Biotech

9.2.28. H3 Biomedicine Inc.

9.2.29. Arcturus Therapeutics

9.2.30. eFFECTOR Therapeutics, Inc.

9.2.31. Ionis Pharmaceuticals, Inc.

9.2.32. Stemirna Therapeutics Co., Ltd.

9.2.33. Skyhawk Therapeutics, Inc.

9.2.34. RNAimmune (Sirnaomics)

9.2.35. Ziphius Therapeutics NV

9.2.36. miRagen Therapeutics, Inc.

9.2.37. Strand Therapeutics Inc.

9.2.38. Other Prominent Players

Global mRNA Synthesis and Manufacturing Services Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 based on Products

  • API
  • Drug Products

Global mRNA Synthesis and Manufacturing Services Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 based on Applications

  • Infectious Disease Vaccines
  • Other Vaccines
  • Therapeutics and Others

Global mRNA Synthesis and Manufacturing Services Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 based on Scale of Operation

  • Research / Preclinical
  • Clinical
  • Commercial

Global mRNA Synthesis and Manufacturing Services Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2030 based on Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

North America mRNA synthesis and manufacturing services market revenue (US$ Million) by Country, 2020 to 2030

  • U.S.
  • Canada

Europe mRNA synthesis and manufacturing services market revenue (US$ Million) by Country, 2020 to 2030

  • Germany
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe

Asia Pacific mRNA synthesis and manufacturing services market revenue (US$ Million) by Country, 2020 to 2030

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America mRNA synthesis and manufacturing services market revenue (US$ Million) by Country, 2020 to 2030

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa mRNA synthesis and manufacturing services market revenue (US$ Million) by Country, 2020 to 2030

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

 Competitive Landscape

  • Company Overview
  • Financial Performance
  • Key Development
  • Latest Strategic Developments

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

 

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

 

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

 

To know more about the research methodology used for this study, kindly contact us/click here.

 

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