mRNA Extraction and Purification Market Size, Share & Trends Analysis Report By Product (Kits/Reagents, Instruments), By Application(Infectious Disease Vaccines, Other Vaccines, Therapeutics and Others), By End-User, By Region, And Segment Forecasts, 2025-2034

Report Id: 1285 Pages: 190 Last Updated: 11 March 2025 Format: PDF / PPT / Excel / Power BI
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Segmentation of mRNA Extraction and Purification Market

Global mRNA Extraction And Purification Market By Product Type

  • Kits
  • Reagents
  • Instruments

 mRNA Extraction and Purification Market

Global mRNA Extraction And Purification Market By Method Type

  • Chromatography
    • Affinity
      • OligodT Chromatography Resins
      • Others
    • Ion Exchange
    • Hydrophobic Interaction
    • Others (Multimodal, Reverse Phase, etc.)
  • Oligo Deoxythymidine (dT) Magnetic Particles
  • Lithium Chloride Precipitation

Global mRNA Extraction And Purification Market By Application

  • Vaccine Production
  • Protein Replacement Therapies
  • Cancer Immunotherapies

Global mRNA Extraction And Purification Market By End-Users, 

  • Biotechnology & Pharmaceutical Companies
  • Contract Research Organizations
  • Academic & Research Institutions

Global mRNA Extraction And Purification Market By Region,

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

North America mRNA Extraction And Purification Market, by Country

  • U.S.
  • Canada

Europe mRNA Extraction And Purification Market, by Country

  • Germany
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe

Asia Pacific mRNA Extraction And Purification Market, by Country

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America mRNA Extraction And Purification Market, by Country

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa mRNA Extraction And Purification Market, by Country

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Chapter 1. Methodology and Scope

1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global MRNA Synthesis Raw Materials Market Snapshot

Chapter 4. Global MRNA Synthesis Raw Materials Market Variables, Trends & Scope

4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis of Metaverse Industry
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. COVID-19 Impact on Metaverse Industry

Chapter 5. Market Segmentation 1: By Product Type Estimates & Trend Analysis

5.1. By Product Type & Market Share, 2034-2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Product Type:

5.2.1. Kits
5.2.2. Reagents
5.2.3. Instruments

Chapter 6. Market Segmentation 2: By Method Type Estimates & Trend Analysis
6.1. By Method Type & Market Share, 2024-2034
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Method Type:

6.2.1. Polymerase Chain Reaction (PCR)
6.2.2. Chromatography

6.2.2.1. Affinity
6.2.2.2. OligodT Chromatography Resins
6.2.2.3. Others
6.2.2.4. Ion Exchange
6.2.2.5. Hydrophobic Interaction
6.2.2.6. Others (Multimodal, Reverse Phase, etc.)

6.2.3. Oligo Deoxythymidine (dT) Magnetic Particles
6.2.4. Lithium Chloride Precipitation

Chapter 7. Market Segmentation 3: By Application Estimates & Trend Analysis
7.1. By Application & Market Share, 2024-2034
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Application:

7.2.1.1. Vaccine Production
7.2.1.2. Protein Replacement Therapies
7.2.1.3. Cancer Immunotherapies

Chapter 8. Market Segmentation 5: By End-User Estimates & Trend Analysis
8.1. By End-User & Market Share, 2024-2034
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By End-User:

8.2.1.1. Hospitals and Clinics
8.2.1.2. Biotechnology & Pharmaceutical Companies
8.2.1.3. Contract Research Organizations
8.2.1.4. Academic & Research Institutions

Chapter 9. MRNA Synthesis Raw Materials Market Segmentation 4: Regional Estimates & Trend Analysis

9.1. North America

9.1.1. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Product Type, 2021-2034
9.1.2. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.1.3. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.1.4. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.1.5. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts by country, 2021-2034

9.2. Europe

9.2.1. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2021-2034
9.2.2. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.2.3. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.2.4. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.2.5. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, 2021-2034

9.3. Asia Pacific

9.3.1. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2021-2034
9.3.2. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.3.3. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.3.4. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.3.5. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, 2021-2034

9.4. Latin America

9.4.1. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2021-2034
9.4.2. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.4.3. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.4.4. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.4.5. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, (US$ Million) 2021-2034

9.5. Middle East & Africa

9.5.1. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, (US$ Million)
9.5.2. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2021-2034
9.5.3. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2021-2034
9.5.4. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2021-2034
9.5.5. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, (US$ Million) 2021-2034

Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles

10.2.1. Qiagen
10.2.2. Thermo Fisher Scientific
10.2.3. Promega Corporation
10.2.4. Agilent Technologies, Inc
10.2.5. Merck Kgaa
10.2.6. Miltenyi Biotec
10.2.7. Biobasic Inc
10.2.8. Takara Bio, Inc
10.2.9. New England Biolabs
10.2.10. Omega Bio-Tek, Inc
10.2.11. Norgen Biotek
10.2.12. Codex DNA, Inc.
10.2.13. Sartorius Stedim Biotech GmbH
10.2.14. Zymo Research
10.2.15. F. Hoffmann-La Roche Ag
10.2.16. Genaxxon Bioscience Gmbh
10.2.17. Biovision
10.2.18. Analytik Jena Ag
10.2.19. Bio-Rad Laboratories, Inc
10.2.20. AccuBioMed
10.2.21. NEBNext Poly(A) mRNA Magnetic Isolation Module
10.2.22. Arraystar, Inc
10.2.23. Fisher BioReagents
10.2.24. CD Bioparticles
10.2.25. United States Biological
10.2.26. Vdo Biotech
10.2.27. Bulldog Bio Inc
10.2.28. Other Prominent Players

Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

New England Biolabs, Omega Bio-Tek, Inc, Norgen Biotek, Zymo Research, F. Hoffmann-La Roche Ag, Genaxxon Bioscience Gmbh, Biovision, Analytik Jena Ag,

The mRNA Extraction and Purification Market is expected to grow at a 21.6% CAGR during the forecast period for 2025-2034.

The mRNA Extraction and Purification Market Size is valued at USD 1105.2 Million in 2024 and is predicted to reach USD 7561.2 Million by the year 2034

Product Type, Method Type, applications, and End-user are the key segments of the mRNA Extraction and Purification Market.

North American region is leading the mRNA Extraction and Purification Market.

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