Neurodegenerative Disease Market Size, Share & Trends Analysis Report By Drug Class (NMDA, SSRIs, Decarboxylase inhibitors, Cholinesterase Inhibitors, Immunomodulators, Dopamine Inhibitors), By Applications, Region And Segment Forecasts, 2025-2034.

Report Id: 1097 Pages: 170 Last Updated: 29 April 2025 Format: PDF / PPT / Excel / Power BI
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Neurodegenerative Disease Market Size is valued at 44.51 Billion in 2024 and is predicted to reach 71.67 Billion by the year 2034 at a 5.0% CAGR during the forecast period for 2025-2034.

Neurodegenerative Disease Market info

It is anticipated to record a CAGR of 4.3% between 2022 and 2030.An umbrella term for a range of conditions that affect neurons in the human brain are referred to as neurodegenerative diseases. Neurons normally don’t replace or reproduce themselves, so when they become damaged or die, they cannot be replaced by the body. Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and/or death of nerve cells. Degenerative nerve diseases include Alzheimer's disease, amyotrophic lateral sclerosis, Friedreich's ataxia, huntington’s disease, Lewy body disease, Parkinson's disease, spinal muscular atrophy.

The market of neurodegenerative disease is boosted by the rising awareness among people and the research and developmental activities undertaken by various research institutions and companies to develop effective therapies to treat them. However, the complex nature of the diseases and the lack of knowledge about their causative factors in most cases hamper the advancement of research and development into effective treatment methods. Current therapies only help to alleviate symptoms rather than curing. Due to rapidly increasing prevalence, Alzheimer's disease and Parkinson's disease pose to be the most challenging diseases. Entry of generics to the already existing products can be a challenge to the market. Reformulating marketed drugs shall provide great opportunities to the neurodegenerative disease market.

Maret Segmentation

The Global market for neurodegenerative disease is fragmented into its drug class and indications. Based on the drug class, the global market is segregated into NMDA, dopamine inhibitors, and SSRIs. On the basis of indications, the market is categorized into Huntington disease, Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and amyotrophic lateral sclerosis. The market is also segmented based on the region Americas, the EMEA, and the APAC.

Some of the molecules under development include VY AADC is gene therapy from Voyager Therapeutics, which is in phase 2 stage of development for the treatment of Parkinson's disease, Crenezumab of Roche is in Phase 3 for Alzheimer’s disease, Gocovri, Ingrezza , Radicava are some of the products approved in 2017 for neurodegenerative diseases.

Competitive Landscape

Some of The Key Players in The Neurodegenerative Disease Market:

  • Novartis
  • Pfizer
  • Merck Serono
  • Biogen Idec
  • TEVA
  • UCB
  • Boehringer Ingelheim
  • Sanofi
  • GlaxoSmithKline
  • Other Prominent Players

The Neurodegenerative Disease Market Report Scope

Report Attribute Specifications
Market Size Value In 2024 USD 44.51 Billion
Revenue Forecast In 2034 USD 71.67 Billion
Growth Rate CAGR CAGR of 5.0% from 2025 to 2034
Quantitative Units Representation of revenue in US$ Billion and CAGR from 2025 to 2034
Historic Year 2021 to 2024
Forecast Year 2025-2034
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Drug Class, By Applications
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; South Korea; South East Asia
Competitive Landscape Novartis, Pfizer, Merck Serono, Biogen Idec, TEVA, UCB, Boehringer Ingelheim, Sanofi, GlaxoSmithKline, and others
Customization Scope Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing and Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Global Neurodegenerative Disease Market Segmentation

Global Neurodegenerative Disease Market by Drug Class

  • NMDA
  • SSRIs
  • Decarboxylase inhibitors
  • Cholinesterase Inhibitors 
  • Immunomodulators
  • Dopamine Inhibitors

Neurodegenerative Disease Market

Global Neurodegenerative Disease Market by Application

  • Parkinson’s Disease
  • Huntington Disease
  • Amyotrophic Lateral Sclerosis
  • Alzheimer’s Disease

Global Neurodegenerative Disease  Market by Region

  • Europe
    • U.K.
    • Germany
    • France
    • Italy
    • Spain
    • Russia
    • Rest of Europe

North America

  • U.S.
  • Canada

Asia Pacific

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

Neurodegenerative Disease Market Size is valued at 44.51 Billion in 2024 and is predicted to reach 71.67 Billion by the year 2034

Neurodegenerative Disease Market is expected to grow at a 5.0% CAGR during the forecast period for 2025-2034.

Novartis, Pfizer, Merck Serono, Biogen Idec, TEVA, UCB, Boehringer Ingelheim, Sanofi, GlaxoSmithKline, and others

Neurodegenerative Disease Market is fragmented into its drug class and indications.

North America region is leading the Neurodegenerative Disease Market .
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