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Global mRNA Extraction and Purification Market

Global mRNA Extraction and Purification Market Size, Share & Trends Analysis Report By Product (Kits/Reagents, Instruments), By Application(Infectious Disease Vaccines, Other Vaccines, Therapeutics and Others), By End-User, By Region, And Segment Forecasts, 2023-2031

Report ID : 1285 | Published : 2023-10-27 | Pages: 190 | Format: PDF/EXCEL

The mRNA Extraction and Purification Market Size is valued at USD 826.0 Million in 2022 and is predicted to reach USD 3972.2 Million by the year 2031 at a 19.6% CAGR during the forecast period for 2023-2031.

mRNA extraction and purification market

Purification and isolation or extraction processes are mandatory for all types of medical research. mRNA Purification and extraction are performed by using different kinds of methods. Many specialized methods are available for extracting mRNAs, such as solution-based and column-based protocols in which column-based techniques are widely used to isolate mRNA. One of the most effective and reliable methods of mRNA isolation is the magnetic separation method with oligo (dT) bound on the surface of paramagnetic beads. The manual process has certainly advanced over time, with various commercial offerings, including complete kits containing most of the components required to isolate nucleic acid. Different reagents, including enzymes and buffers, are used for these processes. Enzymes and buffers containing chaotropic agents such as guanidinium isothiocyanate, sarcosyl, guanidinium chloride, sodium dodecyl sulphate (SDS), urea, phenol, or chloroform are used in extraction and purification processes. In research, mRNA provides critical information about which proteins are being translated and how much transcript is being produced by the cell. Synthetic mRNA production requires a purification step to get the final mRNA product out of the solution in which it was transcribed.

There is an exponential surge in COVID-19 diagnostic testing and vaccine and medication development in laboratories, hospitals, and other testing facilities worldwide. The life science industry is heavily investing in the healthcare industry, and this stimulates the research efforts of biopharmaceutical firms. In order to produce novel goods to fulfil the research needs of the pharmaceutical and biotechnology industries, makers of kits and instruments have also expanded their R&D spending. Omega Bio-tek announced the expansion of its facilities in December 2020 in response to a rise in demand for its DNA/RNA purification kits and automation support services.

RNA isolation & purification kits and automated devices are more expensive than conventional procedures, which may hinder market expansion. This expensive equipment is unaffordable to institutes and firms with lesser R&D resources.

The life science research market in North America and Europe is focused on the usage of RNA purification products, resulting in significant investments, financing, and partnerships for market growth over the projection period.

Market Segmentation

Global mRNA Extraction and Purification Market is segmented by Product Type, Method Type, applications, and End-user. By means of product type segment, it includes Kits, Reagents and Instruments. The Methode Type segment consists of Chromatography ( Affinity ( OligodT Chromatography Resins, Others), Ion Exchange, Hydrophobic Interaction, Others (Multimodal, Reverse Phase, etc.)), Oligo Deoxythymidine (dT) Magnetic Particles, Lithium Chloride Precipitation, whereas by application market is divided into infectious disease vaccines, other vaccines, therapeutics & others. At last end-user segment covers Academics and Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, and Other End Users (Hospitals, etc.).

Competitive Landscape

Some of the key players in the mRNA Extraction and Purification market:

  • Qiagen,
  • Thermo Fisher Scientific,
  • Promega Corporation,
  • Agilent Technologies, Inc,
  • Merck Kgaa,
  • Miltenyi Biotec,
  • Biobasic Inc,
  • Takara Bio, Inc,
  • New England Biolabs,
  • Omega Bio-Tek, Inc,
  • Norgen Biotek,
  • Zymo Research,
  • Hoffmann-La Roche Ag,
  • Genaxxon Bioscience Gmbh,
  • Biovision,
  • Analytik Jena Ag,
  • Bio-Rad Laboratories, Inc,
  • AccuBioMed
  • NEBNext Poly(A) mRNA Magnetic Isolation Module
  • Arraystar, Inc
  • Fisher BioReagents
  • CD Bioparticles
  • United States Biological
  • Vdo Biotech
  • Bulldog Bio Inc

mRNA Extraction and Purification Market Report Scope

Report Attribute

Specifications

Growth rate CAGR

CAGR of 20.17 % from 2023 to 2031

Quantitative units

Representation of revenue in US$ Billion and CAGR from 2023 to 2031

Historic Year

2019 to 2022

Forecast Year

2023-2031

Report coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments covered

By Product Type, Method Type, By Application, By Ene-User

Regional scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia

Competitive Landscape

Qiagen, Thermo Fisher Scientific, Promega Corporation, Agilent Technologies, Inc, Merck Kgaa, Miltenyi Biotec , Biobasic Inc, Takara Bio, Inc, New England Biolabs, Omega Bio-Tek, Inc, Norgen Biotek, Zymo Research, F. Hoffmann-La Roche Ag, Genaxxon Bioscience Gmbh, Biovision, Analytik Jena Ag, Bio-Rad Laboratories, Inc, AccuBioMed, NEBNext Poly(A) mRNA Magnetic Isolation Module, Arraystar, Inc, Fisher BioReagents, CD Bioparticles, United States Biological, Vdo Biotech, Bulldog Bio Inc

Customization scope

Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.

Pricing and available payment methods

Explore pricing alternatives that are customized to your particular study requirements.

Chapter 1. Methodology and Scope

1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global MRNA Synthesis Raw Materials Market Snapshot

Chapter 4. Global MRNA Synthesis Raw Materials Market Variables, Trends & Scope

4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis of Metaverse Industry
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. COVID-19 Impact on Metaverse Industry

Chapter 5. Market Segmentation 1: By Product Type Estimates & Trend Analysis

5.1. By Product Type & Market Share, 2019-2031
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By Product Type:

5.2.1. Kits
5.2.2. Reagents
5.2.3. Instruments

Chapter 6. Market Segmentation 2: By Method Type Estimates & Trend Analysis
6.1. By Method Type & Market Share, 2019-2031
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By Method Type:

6.2.1. Polymerase Chain Reaction (PCR)
6.2.2. Chromatography

6.2.2.1. Affinity
6.2.2.2. OligodT Chromatography Resins
6.2.2.3. Others
6.2.2.4. Ion Exchange
6.2.2.5. Hydrophobic Interaction
6.2.2.6. Others (Multimodal, Reverse Phase, etc.)

6.2.3. Oligo Deoxythymidine (dT) Magnetic Particles
6.2.4. Lithium Chloride Precipitation

Chapter 7. Market Segmentation 3: By Application Estimates & Trend Analysis
7.1. By Application & Market Share, 2019-2031
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By Application:

7.2.1.1. Vaccine Production
7.2.1.2. Protein Replacement Therapies
7.2.1.3. Cancer Immunotherapies

Chapter 8. Market Segmentation 5: By End-User Estimates & Trend Analysis
8.1. By End-User & Market Share, 2019-2031
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By End-User:

8.2.1.1. Hospitals and Clinics
8.2.1.2. Biotechnology & Pharmaceutical Companies
8.2.1.3. Contract Research Organizations
8.2.1.4. Academic & Research Institutions

Chapter 9. MRNA Synthesis Raw Materials Market Segmentation 4: Regional Estimates & Trend Analysis

9.1. North America

9.1.1. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Product Type, 2023-2031
9.1.2. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2023-2031
9.1.3. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2023-2031
9.1.4. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2023-2031
9.1.5. North America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts by country, 2023-2031

9.2. Europe

9.2.1. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2023-2031
9.2.2. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2023-2031
9.2.3. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2023-2031
9.2.4. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2023-2031
9.2.5. Europe MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, 2023-2031

9.3. Asia Pacific

9.3.1. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2023-2031
9.3.2. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2023-2031
9.3.3. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2023-2031
9.3.4. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2023-2031
9.3.5. Asia Pacific MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, 2023-2031

9.4. Latin America

9.4.1. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, 2023-2031
9.4.2. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2023-2031
9.4.3. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2023-2031
9.4.4. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2023-2031
9.4.5. Latin America MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, (US$ Million) 2023-2031

9.5. Middle East & Africa

9.5.1. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) by Product Type, (US$ Million)
9.5.2. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Method Type, 2023-2031
9.5.3. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By Application, 2023-2031
9.5.4. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) estimates and forecasts By End-User, 2023-2031
9.5.5. Middle East & Africa MRNA Synthesis Raw Materials Market revenue (US$ Million) by country, (US$ Million) 2023-2031

Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles

10.2.1. Qiagen
10.2.2. Thermo Fisher Scientific
10.2.3. Promega Corporation
10.2.4. Agilent Technologies, Inc
10.2.5. Merck Kgaa
10.2.6. Miltenyi Biotec
10.2.7. Biobasic Inc
10.2.8. Takara Bio, Inc
10.2.9. New England Biolabs
10.2.10. Omega Bio-Tek, Inc
10.2.11. Norgen Biotek
10.2.12. Codex DNA, Inc.
10.2.13. Sartorius Stedim Biotech GmbH
10.2.14. Zymo Research
10.2.15. F. Hoffmann-La Roche Ag
10.2.16. Genaxxon Bioscience Gmbh
10.2.17. Biovision
10.2.18. Analytik Jena Ag
10.2.19. Bio-Rad Laboratories, Inc
10.2.20. AccuBioMed
10.2.21. NEBNext Poly(A) mRNA Magnetic Isolation Module
10.2.22. Arraystar, Inc
10.2.23. Fisher BioReagents
10.2.24. CD Bioparticles
10.2.25. United States Biological
10.2.26. Vdo Biotech
10.2.27. Bulldog Bio Inc
10.2.28. Other Prominent Players

Segmentation of mRNA Extraction and Purification Market

Global mRNA Extraction And Purification Market By Product Type

  • Kits
  • Reagents
  • Instruments

 mRNA Extraction and Purification Market

Global mRNA Extraction And Purification Market By Method Type

  • Chromatography
    • Affinity
      • OligodT Chromatography Resins
      • Others
    • Ion Exchange
    • Hydrophobic Interaction
    • Others (Multimodal, Reverse Phase, etc.)
  • Oligo Deoxythymidine (dT) Magnetic Particles
  • Lithium Chloride Precipitation

Global mRNA Extraction And Purification Market By Application

  • Vaccine Production
  • Protein Replacement Therapies
  • Cancer Immunotherapies

Global mRNA Extraction And Purification Market By End-Users

  • Biotechnology & Pharmaceutical Companies
  • Contract Research Organizations
  • Academic & Research Institutions

Global mRNA Extraction And Purification Market By Region,

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

North America mRNA Extraction And Purification Market, by Country

  • U.S.
  • Canada

Europe mRNA Extraction And Purification Market, by Country

  • Germany
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe

Asia Pacific mRNA Extraction And Purification Market, by Country

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America mRNA Extraction And Purification Market, by Country

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa mRNA Extraction And Purification Market, by Country

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

Who are the Key Players in the mRNA Extraction and Purification Market?

The mRNA Extraction and Purification Market is expected to grow at a 19.6% CAGR during the forecast period for 2023-2031.

The mRNA Extraction and Purification Market Size is valued at USD 826.0 Million in 2022 and is predicted to reach USD 3972.2 Million by the year 2031.

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