The mRNA Extraction and Purification Market Size is valued at USD 826.0 Million in 2022 and is predicted to reach USD 3972.2 Million by the year 2031 at a 19.6% CAGR during the forecast period for 2023-2031.
Purification and isolation or extraction processes are mandatory for all types of medical research. mRNA Purification and extraction are performed by using different kinds of methods. Many specialized methods are available for extracting mRNAs, such as solution-based and column-based protocols in which column-based techniques are widely used to isolate mRNA. One of the most effective and reliable methods of mRNA isolation is the magnetic separation method with oligo (dT) bound on the surface of paramagnetic beads.
The manual process has certainly advanced over time, with various commercial offerings, including complete kits containing most of the components required to isolate nucleic acid. Different reagents, including enzymes and buffers, are used for these processes. Enzymes and buffers containing chaotropic agents such as guanidinium isothiocyanate, sarcosyl, guanidinium chloride, sodium dodecyl sulphate (SDS), urea, phenol, or chloroform are used in extraction and purification processes. In research, mRNA provides critical information about which proteins are being translated and how much transcript is being produced by the cell. Synthetic mRNA production requires a purification step to get the final mRNA product out of the solution in which it was transcribed.
There is an exponential surge in COVID-19 diagnostic testing and vaccine and medication development in laboratories, hospitals, and other testing facilities worldwide. The life science industry is heavily investing in the healthcare industry, and this stimulates the research efforts of biopharmaceutical firms. In order to produce novel goods to fulfil the research needs of the pharmaceutical and biotechnology industries, makers of kits and instruments have also expanded their R&D spending. Omega Bio-tek announced the expansion of its facilities in December 2020 in response to a rise in demand for its DNA/RNA purification kits and automation support services.
RNA isolation & purification kits and automated devices are more expensive than conventional procedures, which may hinder market expansion. This expensive equipment is unaffordable to institutes and firms with lesser R&D resources.
The life science research market in North America and Europe is focused on the usage of RNA purification products, resulting in significant investments, financing, and partnerships for market growth over the projection period.
Market Segmentation
Global mRNA Extraction and Purification Market is segmented by Product Type, Method Type, applications, and End-user. By means of product type segment, it includes Kits, Reagents and Instruments. The Methode Type segment consists of Chromatography ( Affinity ( OligodT Chromatography Resins, Others), Ion Exchange, Hydrophobic Interaction, Others (Multimodal, Reverse Phase, etc.)), Oligo Deoxythymidine (dT) Magnetic Particles, Lithium Chloride Precipitation, whereas by application market is divided into infectious disease vaccines, other vaccines, therapeutics & others. At last end-user segment covers Academics and Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, and Other End Users (Hospitals, etc.).
Competitive Landscape
Some of the key players in the mRNA Extraction and Purification market:
- Qiagen,
- Thermo Fisher Scientific,
- Promega Corporation,
- Agilent Technologies, Inc,
- Merck Kgaa,
- Miltenyi Biotec,
- Biobasic Inc,
- Takara Bio, Inc,
- New England Biolabs,
- Omega Bio-Tek, Inc,
- Norgen Biotek,
- Zymo Research,
- Hoffmann-La Roche Ag,
- Genaxxon Bioscience Gmbh,
- Biovision,
- Analytik Jena Ag,
- Bio-Rad Laboratories, Inc,
- AccuBioMed
- NEBNext Poly(A) mRNA Magnetic Isolation Module
- Arraystar, Inc
- Fisher BioReagents
- CD Bioparticles
- United States Biological
- Vdo Biotech
- Bulldog Bio Inc
mRNA Extraction and Purification Market Report Scope
Report Attribute |
Specifications |
Growth rate CAGR |
CAGR of 20.17 % from 2023 to 2031 |
Quantitative units |
Representation of revenue in US$ Billion and CAGR from 2023 to 2031 |
Historic Year |
2019 to 2022 |
Forecast Year |
2023-2031 |
Report coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
Segments covered |
By Product Type, Method Type, By Application, By Ene-User |
Regional scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
Country scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia |
Competitive Landscape |
Qiagen, Thermo Fisher Scientific, Promega Corporation, Agilent Technologies, Inc, Merck Kgaa, Miltenyi Biotec , Biobasic Inc, Takara Bio, Inc, New England Biolabs, Omega Bio-Tek, Inc, Norgen Biotek, Zymo Research, F. Hoffmann-La Roche Ag, Genaxxon Bioscience Gmbh, Biovision, Analytik Jena Ag, Bio-Rad Laboratories, Inc, AccuBioMed, NEBNext Poly(A) mRNA Magnetic Isolation Module, Arraystar, Inc, Fisher BioReagents, CD Bioparticles, United States Biological, Vdo Biotech, Bulldog Bio Inc |
Customization scope |
Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape. |
Pricing and available payment methods |
Explore pricing alternatives that are customized to your particular study requirements. |