Global Synthetic Biology Vaccines Market Size is predicted to grow with an 16.00% CAGR during the forecast period for 2025 to 2034.
Synthetic Biology Vaccines Market Size, Share & Trends Analysis Distribution, by Type (mRNA Synthetic Vaccines, Protein/Peptide Synthetic Vaccines, Vector-based Synthetic Vaccines, and DNA Synthetic Vaccines), By Application (Infectious Diseases, Autoimmune & Genetic Diseases, Cancer Immunotherapy, and Pandemic & Epidemic Applications), By Platform Technology (CRISPR-Based Design, Cell-Free Systems, and AI-Assisted Biofabrication), By End-use (Hospitals, Biotech & Pharmaceutical Companies, and Research Institutions), and Segment Forecasts, 2025 to 2034
The development and production of next-generation vaccines using synthetic biology techniques, including gene editing, cell-free expression, and synthetic genomics, is the main focus of the synthetic biology vaccines market. These vaccines have advantages over traditional vaccines in terms of safety and scalability, and they are designed to duplicate or enhance immune responses quickly.
Synthetic biology vaccines enable rapid adaptation to new pathogens and enhanced delivery accuracy by combining DNA/RNA programming, computational biology, and modular bioengineering. The synthetic biology vaccines market is expanding rapidly as demand for faster, more flexible vaccine development platforms worldwide grows.
Furthermore, the rising prevalence of infectious diseases, developing viral outbreaks, and antimicrobial-resistant organisms are pressuring healthcare systems and governments to adopt novel vaccination technologies that enable quick design and large-scale production. Pharmaceutical businesses, biotech firms, and government agencies are increasing their investment in pandemic preparedness initiatives, which is expediting R&D and commercialization. Moreover, the success of synthetic biology-enabled mRNA vaccines during the COVID-19 pandemic has increased confidence among regulators and investors. At the same time, the development of manufacturing infrastructure and collaborations between academia and industry continue to create new opportunities. These factors are expected to drive the synthetic biology vaccines market expansion throughout the forecast period.
Some of the Key Players in Synthetic Biology Vaccines Market:
· Moderna Inc.
· BioNTech SE
· Ginkgo Bioworks Inc.
· Synthetic Genomics Inc.
· Codexis Inc.
· Twist Bioscience Corporation
· DNA Script
· Thermo Fisher Scientific Inc.
· Merck KGaA
· Novartis AG
· Pfizer Inc.
· Sanofi S.A.
· Illumina Inc.
· New England Biolabs
· Synthego Corporation
· GenScript Biotech Corporation
· Arcturus Therapeutics
· CureVac N.V.
· Evonetix Ltd.
· Oxford Biomedica Plc.
The synthetic biology vaccines market is segmented by type, application, platform technology, and end-use. By type, the market is segmented into mRNA synthetic vaccines, protein/peptide synthetic vaccines, vector-based synthetic vaccines, and DNA synthetic vaccines. By application, the market is segmented into infectious diseases, autoimmune & genetic diseases, cancer immunotherapy, and pandemic & epidemic applications. by platform technology, the market is divided into CRISPR-based design, cell-free systems, and AI-assisted biofabrication. By end-use, the market is segmented into hospitals, biotech & pharmaceutical companies, and research institutions.
The mRNA synthetic vaccines segment is rapidly expanding within the synthetic biology vaccine market, owing to its rapid development capabilities, high efficiency, and scalability in pandemic and emerging disease circumstances. Synthetic biology improves mRNA vaccine design by enabling precise sequence optimization, improved delivery mechanisms, and stable formulations, cutting development time from years to months. Moreover, increased investment from biotechnology companies, governments, and global health organizations, particularly in light of the success of mRNA COVID-19 vaccines, has hastened R&D and commercial deployment. The expansion of applications beyond infectious diseases, such as cancer immunotherapy and tailored vaccines, is also supporting the market.
In 2024, the biotechnology & pharmaceutical companies segment had the highest revenue share in the synthetic biology vaccines market. The globalization of synthetic biology methods for vaccine development, production, and discovery is driving the large market share. The pharmaceutical sector has made large investments in synthetic biology vaccines because they have special potential to transform the healthcare sector. Novel biologics have also been developed more quickly due to significant research and development. Furthermore, this segment's leadership has been strengthened by the growing need for effective vaccine manufacture, which was especially noticeable during the COVID-19 pandemic.
The North America region dominated the synthetic biology vaccines market in 2024 due to several factors, including a strong research and development infrastructure. The United States and Canada, in particular, have robust research and development infrastructures. This includes elite academic institutions, research centers, and biotech firms that support innovations and developments in the field of synthetic biology vaccines. Additionally, increased financing and significant public and private sector expenditures on biotechnology and synthetic biology vaccines support improved research and development in this area.
The Asia Pacific market for synthetic biology vaccines is expected to increase significantly in the future years. The number of clinical trials for synthetic biology vaccines and the rise in the prevalence of infectious illnesses are driving this market's growth. Additionally, new healthcare needs and government support for research and development are expected to accelerate the growth of the synthetic biology vaccine market in this region. The market is also growing due to increased investment in the biotechnology sector. The country's market is also being driven by increased government initiatives to introduce next-generation synthetic biology vaccines to the area.
Synthetic Biology Vaccines Market by Type
· mRNA Synthetic Vaccines
· Protein/Peptide Synthetic Vaccines
· Vector-based Synthetic Vaccines
· DNA Synthetic Vaccines
Synthetic Biology Vaccines Market by Application
· Infectious Diseases
· Autoimmune & Genetic Diseases
· Cancer Immunotherapy
· Pandemic & Epidemic Applications
Synthetic Biology Vaccines Market by Platform Technology
· CRISPR-Based Design
· Cell-Free Systems
· AI-Assisted Biofabrication
Synthetic Biology Vaccines Market by End-use
· Hospitals
· Biotech & Pharmaceutical Companies
· Research Institutions
Synthetic Biology Vaccines Market by Region
North America-
· The US
· Canada
Europe-
· Germany
· The UK
· France
· Italy
· Spain
· Rest of Europe
Asia-Pacific-
· China
· Japan
· India
· South Korea
· Southeast Asia
· Rest of Asia Pacific
Latin America-
· Brazil
· Argentina
· Mexico
· Rest of Latin America
Middle East & Africa-
· GCC Countries
· South Africa
· Rest of the Middle East and Africa
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Synthetic Biology Vaccines Market Snapshot
Chapter 4. Global Synthetic Biology Vaccines Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Porter's Five Forces Analysis
4.7. Incremental Opportunity Analysis (US$ MN), 2025-2034
4.8. Global Synthetic Biology Vaccines Market Penetration & Growth Prospect Mapping (US$ Mn), 2024-2034
4.9. Competitive Landscape & Market Share Analysis, By Key Player (2024)
4.10. Use/impact of AI on Synthetic Biology Vaccines Market Industry Trends
Chapter 5. Synthetic Biology Vaccines Market Segmentation 1: By Type, Estimates & Trend Analysis
5.1. Market Share by Type, 2024 & 2034
5.2. Market Size (Value (US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Type:
5.2.1. mRNA Synthetic Vaccines
5.2.2. DNA Synthetic Vaccines
5.2.3. Vector-based Synthetic Vaccines
5.2.4. Protein/Peptide Synthetic Vaccines
Chapter 6. Synthetic Biology Vaccines Market Segmentation 2: By Application, Estimates & Trend Analysis
6.1. Market Share by Application, 2024 & 2034
6.2. Market Size (Value (US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Application:
6.2.1. Infectious Diseases
6.2.2. Cancer Immunotherapy
6.2.3. Autoimmune & Genetic Diseases
6.2.4. Pandemic & Epidemic Applications
Chapter 7. Synthetic Biology Vaccines Market Segmentation 3: By End-use, Estimates & Trend Analysis
7.1. Market Share by End-use, 2024 & 2034
7.2. Market Size (Value (US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following End-use:
7.2.1. Hospitals
7.2.2. Research Institutions
7.2.3. Biotech & Pharmaceutical Companies
Chapter 8. Synthetic Biology Vaccines Market Segmentation 4: By Technology, Estimates & Trend Analysis
8.1. Market Share by Technology, 2024 & 2034
8.2. Market Size (Value (US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Technology:
8.2.1. Cell-Free Systems
8.2.2. CRISPR-Based Design
8.2.3. AI-Assisted Biofabrication
Chapter 9. Synthetic Biology Vaccines Market Segmentation 5: Regional Estimates & Trend Analysis
9.1. Global Synthetic Biology Vaccines Market, Regional Snapshot 2024 & 2034
9.2. North America
9.2.1. North America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Country, 2021-2034
9.2.1.1. US
9.2.1.2. Canada
9.2.2. North America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Type, 2021-2034
9.2.3. North America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Application, 2021-2034
9.2.4. North America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by End-use, 2021-2034
9.2.5. North America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Technology, 2021-2034
9.3. Europe
9.3.1. Europe Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Country, 2021-2034
9.3.1.1. Germany
9.3.1.2. U.K.
9.3.1.3. France
9.3.1.4. Italy
9.3.1.5. Spain
9.3.1.6. Rest of Europe
9.3.2. Europe Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Type, 2021-2034
9.3.3. Europe Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Application, 2021-2034
9.3.4. Europe Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by End-use, 2021-2034
9.3.5. Europe Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Technology, 2021-2034
9.4. Asia Pacific
9.4.1. Asia Pacific Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Country, 2021-2034
9.4.1.1. India
9.4.1.2. China
9.4.1.3. Japan
9.4.1.4. Australia
9.4.1.5. South Korea
9.4.1.6. Hong Kong
9.4.1.7. Southeast Asia
9.4.1.8. Rest of Asia Pacific
9.4.2. Asia Pacific Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Type, 2021-2034
9.4.3. Asia Pacific Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Application, 2021-2034
9.4.4. Asia Pacific Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by End-use, 2021-2034
9.4.5. Asia Pacific Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Technology, 2021-2034
9.5. Latin America
9.5.1. Latin America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Country, 2021-2034
9.5.1.1. Brazil
9.5.1.2. Mexico
9.5.1.3. Rest of Latin America
9.5.2. Latin America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Type, 2021-2034
9.5.3. Latin America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Application, 2021-2034
9.5.4. Latin America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by End-use, 2021-2034
9.5.5. Latin America Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Technology, 2021-2034
9.6. Middle East & Africa
9.6.1. Middle East & Africa Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by country, 2021-2034
9.6.1.1. GCC Countries
9.6.1.2. Israel
9.6.1.3. South Africa
9.6.1.4. Rest of Middle East and Africa
9.6.2. Middle East & Africa Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Type, 2021-2034
9.6.3. Middle East & Africa Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Application, 2021-2034
9.6.4. Middle East & Africa Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by End-use, 2021-2034
9.6.5. Middle East & Africa Synthetic Biology Vaccines Market Revenue (US$ Mn) Estimates and Forecasts by Technology, 2021-2034
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. Moderna Inc. (USA)
10.2.1.1. Business Overview
10.2.1.2. Key Product/Service
10.2.1.3. Financial Performance
10.2.1.4. Geographical Presence
10.2.1.5. Recent Developments with Business Strategy
10.2.2. BioNTech SE (Germany)
10.2.3. Ginkgo Bioworks Inc. (USA)
10.2.4. Synthetic Genomics Inc. (USA)
10.2.5. Codexis Inc. (USA)
10.2.6. Twist Bioscience Corporation (USA)
10.2.7. DNA Script (France)
10.2.8. Thermo Fisher Scientific Inc. (USA)
10.2.9. Merck KGaA (Germany)
10.2.10. Novartis AG (Switzerland)
10.2.11. Pfizer Inc. (USA)
10.2.12. Sanofi S.A. (France)
10.2.13. Illumina Inc. (USA)
10.2.14. New England Biolabs (USA)
10.2.15. Synthego Corporation (USA)
10.2.16. GenScript Biotech Corporation (China)
10.2.17. Arcturus Therapeutics (USA)