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Isothermal Nucleic Acid Amplification Technology Market

Isothermal Nucleic Acid Amplification Technology Market Size, Share & Trends Analysis Report By Product (Assays, Kits & Reagents, Systems), By Technology, By Application, By End-User, By Region, And By Segment Forecasts, 2024-2031

Report ID : 2001 | Published : 2024-10-18 | Pages: 180 | Format: PDF/EXCEL

The Isothermal Nucleic Acid Amplification Technology Market Size is valued at USD 4.53 Bn in 2023 and is predicted to reach USD 8.91 Bn by the year 2031 at a 8.94% CAGR during the forecast period for 2024-2031. 

Key Industry Insights & Findings from the Report: 

  • Increasing disposable income and better healthcare facilities in emerging countries should boost the isothermal nucleic acid amplification technology industry.
  • Isothermal nucleic acid amplification technology has surged due to high demand in research and development activities and an increased focus on biomarker discovery.
  • North America dominated the market and accounted for a revenue share of global revenue in 2023.
  • The regulatory structure that controls the creation and utilization of INAAT-based diagnostic and therapeutic techniques is a big roadblock limiting the market's development. 

Isothermal Nucleic Acid Amplification Technology Market

The Isothermal Nucleic Acid Amplification Technology (INAAT) is seeing a significant increase in demand as a molecular testing technique, owing mostly to the increasing prevalence of infectious diseases. Infectious diseases such as hepatitis, influenza, and others are among the main causes of death, particularly in underdeveloped nations. As a result, the demand for quick, easy-to-use, disease-specific testing alternatives is predicted to drive up the adoption of INAAT solutions. 

Rapid advancements in existing amplification technologies, as well as the development of technologies such as Single Primer Isothermal Amplification, Loop-Mediated Isothermal Amplification, Recombinase Polymerase Amplification, and others, are paving the way for new INAAT product applications. For example, in June 2022, a research study published in the Analyst Journal demonstrated the creation of smartphone-integrated equipment that can rapidly test for the Zika virus in a single blood drop utilizing LAMP technology. Such advancements are likely to increase the technique's commercial penetration shortly. 

Competitive Landscape:

Some major key players in the Isothermal Nucleic Acid Amplification Technology Market:

  • Grifols, S.A. (Spain),
  • Hologic, Inc. (US),
  • Abbott Laboratories (US),
  • Becton, Dickinson and Company (US),
  • Meridian Bioscience (US),
  • Eiken Chemical Co., Ltd. (Japan),
  • bioMérieux SA (France),
  • Tecan Trading AG (Switzerland),
  • New England Biolabs (US),
  • QIAGEN N.V. (Germany),
  • DiaSorin Sp.A. (Italy),
  • General Electric (US),
  • OptiGene Limited (UK),
  • Quidel Corporation (US),
  • Thermo Fisher Scientific (US).
  • Genomtec (Poland),
  • Mast Group Ltd. (UK),
  • Ustar Biotechnologies (China),
  • Jena Bioscience GmbH (Germany),
  • Atila BioSystems (US),
  • TwistDx Limited (UK),
  • LGC Limited (UK),
  • Life Sciences Advanced Technologies (US),
  • GenoSensor Corporation (US),
  • PCR Biosystems (UK) 

Market Segmentation: 

The INAAT market has been divided based on product, technology, application, and end-user. The market is segmented as assays and systems based on product. The technology segment includes TMA, LAMP, SDA, NASBA, SPIA, NEAR, and HDA. The application segment includes diagnosis, blood screening, and other applications. As per the end-users, the market is bifurcated into hospitals, reference laboratories, academic & research laboratories, and other end-users. 

Based On Technology, The LAMP Segment Is Accounted As A Major Contributor In The Isothermal Nucleic Acid Amplification Technology Market

The highest market share was held by loop-mediated isothermal amplification (LAMP). The method allows for several detection modes, such as real-time fluorescence using intercalators, lateral flow, and agarose gel detection. As a result, the approach can detect a wide spectrum of RNA and DNA targets in human samples, including the Zika virus and SARS-CoV-2 virus. Furthermore, the technique's resistance to inhibitors allows it to be used with crude samples and little processed nucleic acids, which increasesdemand. 

The Hospital Segment Witnessed The Development At A Rapid Rate 

The hospital segment dominated the market. This is due to the introduction of miniaturized point-of-care INAAT equipment that allows for single-level access for hospital-based analysis. Similarly, the increased throughput and automation provided by such technologies for the processing of a high number of samples are likely to drive market expansion. 

In The Region, The North America Isothermal Nucleic Acid Amplification Technology Market Holds A Significant Revenue Share 

North America dominated the market due to the region's existing research infrastructure and rising demand for nucleic acid amplification-based diagnostics for infectious disease prevention. Furthermore, high per capita healthcare spending and a growing emphasis on point-of-care diagnostic methods are expected to boost market expansion. 

Recent Developments

  • In May 2022, Meridian Bioscience launched Lyo-Ready™ Saliva-Specific Isothermal Amplification Master Mixes for direct detection of DNA & RNA in point-of-care diagnostic assays. Lyo-Ready™ Direct DNA LAMP Saliva Mix and Lyo-Ready™ Direct RNA/DNA LAMP Saliva Mix were the first isothermal mixes specifically designed for saliva and sputum samples, and they were compatible with lyophilization.
  • In March 2022, Thermo Fisher Scientific introduced two novel solutions based on reverse transcription loop-mediated isothermal amplification (RT-LAMP). The isothermal RT-LAMP method, which relies on nucleic acid amplification, offers a fast and cost-effective approach for detecting viral pathogens

Isothermal Nucleic Acid Amplification Technology Market Report Scope:

Report Attribute

Specifications

Market Size Value In 2023

USD 4.53 Bn

Revenue Forecast In 2031

USD 8.91 Bn

Growth Rate CAGR

CAGR of 8.94% from 2024 to 2031

Quantitative Units

Representation of revenue in US$ Million and CAGR from 2024 to 2031

Historic Year

2019 to 2023

Forecast Year

2024-2031

Report Coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments Covered

By Product, Technology, Application, End-User

Regional Scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country Scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia

Competitive Landscape

Grifols, S.A. (Spain), Hologic, Inc. (US), Abbott Laboratories (US), Becton, Dickinson and Company (US), Meridian Bioscience (US), Eiken Chemical Co., Ltd. (Japan), bioMérieux SA (France), Tecan Trading AG (Switzerland), New England Biolabs (US), QIAGEN N.V. (Germany), DiaSorin Sp.A. (Italy), General Electric (US), OptiGene Limited (UK), Quidel Corporation (US), Thermo Fisher Scientific (US). Genomtec (Poland), Mast Group Ltd. (UK), Ustar Biotechnologies (China), Jena Bioscience GmbH (Germany), Atila BioSystems (US), TwistDx Limited (UK), LGC Limited (UK), Life Sciences Advanced Technologies (US), GenoSensor Corporation (US), and PCR Biosystems (UK).

Customization Scope

Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.

Pricing And Available Payment Methods

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Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global Isothermal Nucleic Acid Amplification Technology Market Snapshot

Chapter 4. Global Isothermal Nucleic Acid Amplification Technology Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. COVID-19 Impact Analysis

Chapter 5. Market Segmentation 1: By Product Estimates & Trend Analysis
5.1. By Product & Market Share, 2023-2031
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2019 to 2031 for the following By Product:

5.2.1. Assays, Kits, & Reagents
5.2.2. Systems

Chapter 6. Market Segmentation 2: By Application Estimates & Trend Analysis
6.1. By Product & Market Share, 2023-2031
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2019 to 2031 for the following By Application:

6.2.1. Disease Diagnosis

6.2.1.1. Hepatitis
6.2.1.2. Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG)
6.2.1.3. Influenza
6.2.1.4. Covid-19
6.2.1.5. Other Disease Diagnosis

6.2.2. Blood Screening
6.2.3. Other Applications

Chapter 7. Market Segmentation 3: By Technology Estimates & Trend Analysis
7.1. By Product & Market Share, 2023-2031
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2019 to 2031 for the following By Technology:

7.2.1. Transcription Mediated Amplification (TMA)
7.2.2. Loop-mediated Isothermal Amplification (LAMP)
7.2.3. Strand Displacement Amplification (SDA)
7.2.4. Helicase-dependent Amplification (HDA)
7.2.5. Nucleic Acid Sequence-based Amplification (NASBA)
7.2.6. Nicking Enzyme Amplification Reaction (NEAR)
7.2.7. Single Primer Isothermal Amplification (SPIA)
7.2.8. Other Technologies

Chapter 8. Market Segmentation 4: By End User Estimates & Trend Analysis
8.1. By Product & Market Share, 2023-2031
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2019 to 2031 for the following By End User:

8.2.1. Hospitals
8.2.2. Reference Laboratories
8.2.3. Academic & Research Institutes
8.2.4. Other End Users

Chapter 9. Isothermal Nucleic Acid Amplification Technology Market Segmentation 5: Regional Estimates & Trend Analysis

9.1. North America

9.1.1. North America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Product, 2024-2031
9.1.2. North America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Application, 2024-2031
9.1.3. North America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Technology, 2024-2031
9.1.4. North America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By, End User 2024-2031
9.1.5. North America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By country, 2024-2031

9.1.5.1. U.S.
9.1.5.2. Canada

9.2. Europe

9.2.1. Europe Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Product, 2024-2031
9.2.2. Europe Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Application, 2024-2031
9.2.3. Europe Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Technology, 2024-2031
9.2.4. Europe Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By End User ,2024-2031
9.2.5. Europe Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By country, 2024-2031

9.2.5.1. Germany
9.2.5.2. Poland
9.2.5.3. France
9.2.5.4. Italy
9.2.5.5. Spain
9.2.5.6. UK
9.2.5.7. Rest of Europe

9.3. Asia Pacific

9.3.1. Asia Pacific Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Product, 2024-2031
9.3.2. Asia Pacific Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Application, 2024-2031
9.3.3. Asia Pacific Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Technology, 2024-2031
9.3.4. Asia Pacific Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By End User, 2024-2031 

9.3.5. Asia Pacific Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By country, 2024-2031

9.3.5.1. China
9.3.5.2. India
9.3.5.3. Japan
9.3.5.4. Australia
9.3.5.5. Rest of Asia Pacific

9.4. Latin America

9.4.1. Latin America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Product, 2024-2031
9.4.2. Latin America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Application, 2024-2031
9.4.3. Latin America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Technology, 2024-2031
9.4.4. Latin America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By End User, 2024-2031
9.4.5. Latin America Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By country, 2024-2031

9.4.5.1. Brazil
9.4.5.2. Rest of Latin America

9.5. Middle East & Africa

9.5.1. Middle East & Africa Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Product, 2024-2031
9.5.2. Middle East & Africa Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Application, 2024-2031
9.5.3. Middle East & Africa Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By Technology, 2024-2031
9.5.4. Middle East & Africa Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By End User, 2024-2031
9.5.5. Middle East & Africa Isothermal Nucleic Acid Amplification Technology Market revenue (US$ Million) estimates and forecasts By country, 2024-2031

9.5.5.1. South Africa
9.5.5.2. GCC Countries
9.5.5.3. Rest of MEA

Chapter 10. Competitive Landscape

10.1. Major Mergers and Acquisitions/Strategic Alliances

10.2. Company Profiles

10.2.1. Hologic, Inc.
10.2.2. Abbott Laboratories
10.2.3. Grifols, S.A.
10.2.4. Becton, Dickinson And Company
10.2.5. Meridian Bioscience
10.2.6. Eiken Chemical Co., Ltd.
10.2.7. Quidel Corporation
10.2.8. Qiagen N.V.
10.2.9. New England Biolabs
10.2.10. Diasorin S.P.A.
10.2.11. Biomérieux Sa
10.2.12. Tecan Trading Group
10.2.13. General Electric Company
10.2.14. Thermo Fisher Scientific
10.2.15. Optigene Limited
10.2.16. Other Companies

Segmentation of Isothermal Nucleic Acid Amplification Technology Market-

Isothermal Nucleic Acid Amplification Technology Market By Product-

  • Assays, Kits & Reagents
  • Systems 

Isothermal Nucleic Acid Amplification Technology Market

Isothermal Nucleic Acid Amplification Technology Market By Technology-

  • Transcription Mediated Amplification (TMA)
  • Loop-mediated Isothermal Amplification (LAMP)
  • Strand Displacement Amplification (SDA)
  • Helicase-dependent Amplification (HDA)
  • Nucleic Acid Sequence-based Amplification (NASBA)
  • Nicking Enzyme Amplification Reaction (NEAR)
  • Single Primer Isothermal Amplification (SPIA)
  • Other Technologies

Isothermal Nucleic Acid Amplification Technology Market By Application-

  • Disease Diagnosis
    • Hepatitis
    • Chlamydia trachomatis (CT)
    • Neisseria gonorrhoeae (NG)
    • Influenza
    • Covid-19
    • Other Disease Diagnosis
  • Blood Screening
  • Other Applications

By End-User-

  • Hospitals
  • Reference Laboratories
  • Academic & Research Institutes
  • Other End users

By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • South East Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

How big is the Isothermal Nucleic Acid Amplification Technology Market?

Isothermal Nucleic Acid Amplification Technology Market expected to grow at a 8.94% CAGR during the forecast period for 2024-2031

Grifols, S.A. (Spain), Hologic, Inc. (US), Abbott Laboratories (US), Becton, Dickinson and Company (US), Meridian Bioscience (US), Eiken Chemical Co.

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