The Global Nucleic acid therapeutics CDMO Market size was valued at US$ 1.93 billion in 2021 and is expected to grow at a compound annual growth rate (CAGR) of 10.7% from 2022 to 2030. Nucleic acid therapeutics deal with nucleic acids (DNA and RNA) or other related chemical compounds. The nucleic acid therapeutics CDMO market is estimated to show high growth over the next few years, driven by the high application potential of nucleic acids for a variety of medical conditions. In addition, the increasing preference for personalized medicine also propels the market growth. Furthermore, continued research and development activities for manufacturing innovative nucleic acid therapeutics are forcing pharmaceutical companies to expand their businesses. Most companies focus on partnerships, acquisitions, collaborations, and mergers with contract development and manufacturing organizations (CDMOs) to seamlessly scale oligonucleotides from research to commercial manufacturing. Therefore, scaling up the products cost-effectively and efficiently from research to commercial quantities is a key challenge to CDMOs.
Other driving factors of the nucleic acid therapeutics CDMO market include the growing demand for nucleic acid therapeutics and the high prevalence of chronic and genetic diseases. Furthermore, advancements in nucleic acid technologies, a rise in R&D investments, increasing FDA approvals of nucleic acid therapeutics, and growing CDMO partnerships and acquisitions are expected to escalate the nucleic acid therapeutics CDMO market growth over the forecast years. However, mass production at low cost, lack of expertise in developing nucleic acid therapeutics, and supply chain challenges are anticipated to hinder the industry growth.
The nucleic acid therapeutics CDMO market is segmented by technology (Column-Based Method and Microarray-Based Method), products (Standard Nucleic Acid, Micro-Scale Nucleic Acid, Large-Scale Nucleic Acid, Custom Nucleic Acid, Modified Nucleic Acid, Primers, Probes, Other Nucleic Acid, and Other Services), end-users (Pharmaceutical Companies, Academic Research Institute, Diagnostic Laboratories), and geography (North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa). North America holds the highest share of this market.
Some of the key players of Nucleic acid therapeutics CDMO market are Agilent Technologies, Inc., Ajinomoto Co. Inc., Bachem Holding AG., Biospring GmbH, Corden Pharma International, Danaher Corporation, Guangzhou Ruibo Biotechnology Co., Ltd., KNC Laboratories Co., Ltd., LGC Limited, Merck KGaA, Nippon Shokubai Co., Ltd., Nitto Denko Avecia Inc, QIAGEN N.V., ST Pharm Co Ltd, Sumitomo Chemical Co., Ltd., Syngene International Limited, Thermo Fisher Scientific Inc., Wuxi AppTec, Yamasa Corporation, Laboratorios Farmacéuticos Rovi, S.A., Sartorius AG (BIA Separations), AGC Biologics, FUJIFILM Diosynth Biotechnologies, Hanmi Pharmaceutical, Arranta Bio (Recipharm), ST Pharm, BioCina Pty Ltd., Curia Global, Inc. and Other Prominent Players.