Targeted Sequencing Market Size, Share & Trends Analysis Report By Product Type (Instruments, Kits/Panels And Assays, Services), Target Enrichment Method (Hybridization Capture, Amplicon Sequencing), Type Of Target Capture (Targeted DNA Sequencing, Targeted RNA Sequencing), Application, And End-User, By Region, And Segment Forecasts, 2025-2034

Report Id: 1658 Pages: 180 Last Updated: 04 July 2025 Format: PDF / PPT / Excel / Power BI
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Global Targeted Sequencing Market Size is valued at USD 3.9 Bn in 2024 and is predicted to reach USD 14.7 Bn by the year 2034 at a 14.4% CAGR during the forecast period for 2025-2034. 

Key Industry Insights & Findings from the Report:

  • The demand for personalized treatment strategies is a significant driver for the targeted sequencing market.
  • Targeted sequencing offers opportunities to detect cancer-related mutations, driving the targeted sequencing market.
  • North America dominated the market and accounted for a global revenue share in 2024.
  • The key challenge for the targeted sequencing market is the presence of technological obsolescence. 

Targeted Sequencing Market

A specific group of genes or genome regions are identified and sequenced in the process known as targeted sequencing. Researchers are able to focus their time, resources, and data analysis on specific areas of interest due to targeted sequencing, which also allows sequencing at significantly higher coverage levels. A large range of targeted sequencing library prep kits are available, including kits with probe sets centered on specific fields of interest such as cancer, cardiomyopathy, or autism.

Expansion of genome mapping initiatives, the expansion of next-generation sequencing (NGS) applications, rising healthcare costs, and technological advancements in sequencing platforms are all causing the targeted sequencing market development during the forecast period. Furthermore, major companies all over the globe have strengthened their R&D capacities. This heavy emphasis on COVID-19 vaccine research provided a lucrative opportunity for NGS adoption throughout the pandemic period. For example, a group of Chinese researchers used the Oxford Nanopore Technologies (U.K.) product MinION Mk1C to sequence COVID-19 samples.

However, the lack of skilled professionals and ethical and regulatory restrictions related to targeted sequencing technology are anticipated to hinder market development over the projection period. 

Recent Developments:

  • In January 2023, Agilent Technologies Inc. unveiled its latest acquisition: Avida Biomed, a pioneering player in the life sciences sector. Avida Biomed specializes in crafting cutting-edge target enrichment workflows tailored for clinical researchers who leverage next-generation sequencing (NGS) methods to delve into cancer studies.. 

Competitive Landscape:

Some of the Targeted Sequencing Market players are:

  • Agilent Technologies, Inc.
  • Azenta US, Inc. (GENEWIZ)
  • BGI Group (MGI Tech Co., Ltd.)
  • CD Genomics
  • Daicel Corporation (Daicel Arbor Biosciences)
  • (Integrated DNA Technologies, Inc.)
  • Hoffmann-La Roche Ltd
  • Illumina, Inc.
  • LGC Limited (LGC Biosearch Technologies)
  • PerkinElmer Inc.
  • Psomagen
  • QIAGEN N.V.
  • Takara Bio Inc.
  • Tecan Trading AG
  • Thermo Fisher Scientific Inc.
  • Twist Bioscience

Market Segmentation:

The targeted sequencing market is segmented on the basis of product type, target enrichment method, type of target capture, application, and end-user. On the basis of product type, the market is segregated into instruments, kits/panels and assays, services, and other product types. By target enrichment method, the market is segmented into hybridization capture, amplicon sequencing, and other Target Enrichment Methods.

The target capture segments include targeted DNA sequencing, targeted RNA sequencing, and other types of target capture. By application, the market is segmented into oncology, reproductive health, hereditary diseases, neurological disorders, infectious diseases, cardiovascular diseases, rare diseases, and other applications. The end-user segment includes diagnostic and clinical laboratories, academic and research institutions, pharmaceutical & biotech companies, and other end users.

Based On Application, The Oncology Segment Is Accounted As A Major Contributor In The Targeted Sequencing Market

The oncology category is expected to hold a major share of the global Targeted Sequencing Market in 2024. This is attributed to the number of diagnostic methods, and cancer treatment rates are growing along with the frequency of the disease. 18.1 million new cases of cancer were recorded in 2018, and the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO) predicts that the number will rise to 24.1 million cases by 2030 and 29.5 million new cases by 2040. Therefore, there is a growing market for next-generation sequencing technologies due to the increasing need for cancer therapy, related medications, and genetic analysis techniques to find anomalies in gene expression and function.

Diagnostic And Clinical Laboratories Segment Witness Growth At A Rapid Rate

The diagnostic and clinical laboratories segment is projected to boost at a rapid rate in the global targeted sequencing market. Due to their easy accessibility, a growing number of cancer patients are visiting diagnostic labs for diagnosis and treatment, propelling the next-generation sequencing market for this end-user sector. The development of the next-generation sequencing market for clinical diagnostic laboratories is also supported by improvements in healthcare infrastructure in both developed and developing countries.

The North America Targeted Sequencing Market Holds A Significant Revenue Share In The Region

The North America Targeted Sequencing Market is expected to register the highest market share in terms of revenue in the near future. With the COVID-19 epidemic in the area, targeted sequencing technology is becoming more and more common as a standard clinical diagnostic test. For instance, the United States (U.S.) Food and Drug Administration received Breakthrough Device Designation for Pathogenomix Inc.'s Patho-Seq assay in January 2022. This firm specializes in next-generation sequencing pathogen diagnostics (FDA). Moreover, the Asia-Pacific region is anticipated to grow at the fastest rate over the projection period owing to the region's rapid economic development, rising cancer incidence, and increased government attention to the improvement of the healthcare sector.

Other prominent growth drivers of the Asia-Pacific next-generation sequencing market include government initiatives and funding for extensive genome sequencing studies to develop targeted medications.

Targeted Sequencing Market Report Scope:

Report Attribute Specifications
Market size value in 2024 USD 3.9 Bn
Revenue forecast in 2034 USD 14.7 Bn
Growth rate CAGR CAGR of 14.4% from 2025 to 2034
Quantitative units Representation of revenue in US$ Billion, and CAGR from 2025 to 2034
Historic Year 2021 to 2024
Forecast Year 2025-2034
Report coverage The forecast of revenue, the position of the company, the competitive market statistics, growth prospects, and trends
Segments covered Product Type, Target Enrichment Method, Type Of Target Capture, Application, And End-User
Regional scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; Southeast Asia; South Korea; Southeast Asia
Competitive Landscape Agilent Technologies, Inc., Azenta US, Inc. (GENEWIZ), BGI Group (MGI Tech Co., Ltd.), CD Genomics, Daicel Corporation (Daicel Arbor Biosciences), Danaher. (Integrated DNA Technologies, Inc.), F. Hoffmann-La Roche Ltd, Illumina, Inc., LGC Limited (LGC Biosearch Technologies), PacBio., PerkinElmer Inc., Psomagen, QIAGEN N.V., Takara Bio Inc., Tecan Trading AG, Thermo Fisher Scientific Inc., Twist Bioscience.
Customization scope Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing and available payment methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of Targeted Sequencing Market-

Targeted Sequencing Market By Product Type-

  • Instruments
  • Kits/Panels and Assays
  • Services
  • Other Product Types 

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Targeted Sequencing Market By Target Enrichment Method-

  • Hybridization Capture
  • Amplicon Sequencing
  • Other Target Enrichment Methods

Targeted Sequencing Market By Type of Target Capture -

  • Targeted DNA Sequencing
    • Targeted Methyl Sequencing
  • Targeted RNA Sequencing
    • Targeted Metagenomic Sequencing
  • Other Types of Target Capture

Targeted Sequencing Market By Application-

  • Oncology
    • Solid Tumor
    • Liquid Biopsy
    • Minimal Residual Disease Testing
    • Circulating Tumor Cell (CTC) Analysis
  • Infectious Diseases
  • Cardiovascular Diseases
  • Reproductive Health
    • Carrier Screening
    • Non-Invasive Prenatal Testing
    • Preimplantation Genetic Diagnosis (PGD)
    • Newborn Screening
  • Rare Diseases
  • Neurological Disorders
  • Hereditary Diseases
  • Other Applications

Targeted Sequencing Market By End-User-

  • Diagnostic and Clinical Laboratories
  • Academic and Research Institutions
  • Pharmaceutical and Biotech Companies
  • Other End Users

Targeted Sequencing Market By Region-

North America-

  • The US
  • Canada

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • South East Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

Targeted Sequencing Market Size is valued at USD 3.9 Bn in 2024 and is predicted to reach USD 14.7 Bn by the year 2034

Targeted Sequencing Market expected to grow at a 14.4% CAGR during the forecast period for 2025-2034

Agilent Technologies, Inc., Azenta US, Inc. (GENEWIZ), BGI Group (MGI Tech Co., Ltd.), CD Genomics, Daicel Corporation (Daicel Arbor Biosciences)

Product Type, Target Enrichment Method, Type Of Target Capture, Application, and End-User are the key segments of the Targeted Sequencing Market.

North America region is leading the Targeted Sequencing Market
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