Gene Therapy For Retinal Diseases Market Size, Share & Trends Analysis Report By Indication (Choroideremia (CHM), Leber Congenital Amaurosis, Leber’s Hereditary Optic Neuropathy, X-Linked Retinitis Pigmentosa, and Other Indications), Region And Segment Forecasts, 2023-2031.

Report Id: 1157 Pages: 180 Last Updated: 08 November 2024 Format: PDF / PPT / Excel / Power BI
Share With : linkedin twitter facebook

The Gene Therapy For Retinal Diseases Market is expected to grow at an 8.0 % CAGR during the forecast period for 2023-2031.

Gene Therapy For Retinal Diseases Market

Gene therapy states a method of announcing foreign DNA constructs into host cells in demand to treat various medical conditions, including retinal diseases. Gene therapy has an increasing research potential, mainly in the arena of retinal and ophthalmic diseases. The main features of the eye include convenience in terms of surgical interventions and injections and fitted blood-ocular barriers that bar other organs from undesirable contamination. The high potential of gene therapy to treat ocular diseases is boosting the demand for the market globally. Additionally, the approval of the first gene therapy for retinal diseases in 2017 is expected to increase the demand in the coming years.

The presence of several drugs under clinical trials and their positive results are expected to generate immense opportunities for market growth over the forecast period. The evidence of the use of the gene as a medicine has come a long way and establishes its position in treating retinal disease. Certainly, with only limited availability of treatment options for retinal diseases, gene therapy has been established safe, feasible, and effective and could lead to robust effects after a single injection. Moreover, growing strategic partnerships and acquisitions among the key players operating in the market are expected to significantly propel market growth. However, the high cost associated with gene therapy may affect the growth of gene therapy in the retinal disease market. However, growing demand for modified and effective treatment and rising research funding globally is estimated to drive the market growth substantially during the estimated time frame.

Market Segmentation

The Global Gene Therapy for Retinal Diseases Market is segmented on the basis of indication, and region. Based on the indication, the market is divided into Choroideremia (CHM), Leber congenital amaurosis, Leber’s hereditary optic neuropathy, X-linked retinitis pigmentosa, and Other Indication. Based on the region, the market is studied across North America, Asia-Pacific, Europe, and the Rest of the World. North America accounted for the significant share in the gene therapy for retinal disease market, followed by Europe. A large number of research laboratories and biopharmaceutical companies operating in the market are contributing towards the high share of the region in the global market. Additionally, well-established healthcare infrastructure in the U.S. and the high adoption of advanced technologies for treatment are propelling the growth of U.S. gene therapy for the retinal diseases market.

Competitive Landscape

Some of The Key Players in The Gene Therapy For Retinal Diseases Market:

  • Applied Genetic Technologies Corporation
  • Adverum Biotechnologies
  • ProQR Therapeutics
  • MeiraGTx Limited.
  • Oxford BioMedica
  • Horama S.A.
  • Gensight Biologics
  • Regenxbio Inc.
  • Spark Therapeutics, Inc.
  • Genzyme (Sanofi)
  • Novartis Pharmaceuticals
  • Nightstar Therapeutics (Biogen)
  • Hemera Biosciences
  • ViGeneron GmbH
  • Allergan
  • Eyevensys
  • Clearside Biomedical
  • IVERIC bio, Inc.
  • Other Prominent Players

The Gene Therapy For Retinal Diseases Market Report Scope

Report Attribute Specifications
Growth Rate CAGR CAGR of 8.0 % from 2023 to 2031
Quantitative Units Representation of revenue in US$ Million and CAGR from 2023 to 2031
Historic Year 2019 to 2022
Forecast Year 2023-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Indication
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia
Competitive Landscape Applied Genetic Technologies Corporation, Adverum Biotechnologies, ProQR Therapeutics, MeiraGTx Limited., Oxford BioMedica, Horama S.A., Gensight Biologics, Regenxbio Inc., Spark Therapeutics, Inc., Genzyme (Sanofi), Novartis Pharmaceuticals, Nightstar Therapeutics (Biogen), Hemera Biosciences, Allergan, and others
Customization Scope Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing and Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Global Gene Therapy for Retinal Diseases Market Segmentation:

Global Gene Therapy for Retinal Diseases Market by Indication

  • Choroideremia (CHM)
  • Leber congenital amaurosis
  • Leber’s hereditary optic neuropathy
  • X-linked retinitis pigmentosa
  • Other Indication

Gene Therapy For Retinal Diseases Market

Global Gene Therapy for Retinal Diseases Market Based on Region

  • Europe
  • Germany
  • Poland
  • France
  • Italy
  • Spain
  • UK
  • Rest of Europe
  • North America
  • U.S.
  • Canada
  • Asia Pacific
  • India
  • China
  • Japan
  • Australia
  • Rest of Asia Pacific
  • Rest of World

Need specific information/chapter from the report of the custom data table, graph or complete report? Tell us more.

Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

Name field cannot be blank!
Email field cannot be blank!(Use email format)
Designation field cannot be blank!
Company field cannot be blank!
Contact No field cannot be blank!
Message field cannot be blank!
8072
Security Code field cannot be blank!

Frequently Asked Questions

The Gene Therapy For Retinal Diseases Market is expected to grow at an 8.0 % CAGR during the forecast period for 2023-2031.

Applied Genetic Technologies Corporation, Adverum Biotechnologies, ProQR Therapeutics, MeiraGTx Limited., Oxford BioMedica, Horama S.A., Gensight Biol

Indication is the key segments of the Gene Therapy For Retinal Diseases Market.

North American region is leading the Gene Therapy For Retinal Diseases Market.
Get Sample Report Enquiry Before Buying