Fragment-Based Drug Discovery Market Size, Share & Trends Analysis Report By Technique (X-ray Crystallography, Nuclear Magnetic Resonance, Surface Plasmon Resonance. and Other Screening Techniques), By Service, By End Users, Region And Segment Forecasts, 2023-2031.

Report Id: 1175 Pages: 180 Last Updated: 16 October 2024 Format: PDF / PPT / Excel / Power BI
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The Fragment-Based Drug Discovery Market is expected to grow at a 11.0 % CAGR during the forecast period for 2023-2031.

Fragment-Based Drug Discovery Market

Fragment-based Drug Discovery is being used to find similar compounds like lead in drug discovery process, which is based on identification of chemical fragments, this chemical fragment may be biological target or on combining them produce a lead molecule.

Increasing novel complex medical problems creating the demand for newer fragment-based drug discovery. Moreover, as a result of increasing demand, the market for fragment-based drug discovery dominating the biopharmaceutical companies. The upsurge in technology for biophysical fragment screening is become key drivers of global fragment-based drug discovery market. Moreover, these systems providing promising access in creating chemical with similar properties like lead.  Additionally, the fragment-based drug discovery systems found to be useful in marking out chemical series molecule from multiple targets, also pharmaceutical companies have increases the spending on research and development expected to create the lucrative growth in market near the future.

Market Segmentation

The Global Fragment-based Drug Discovery market is segmented on the basis of technique, service, end users and region. Based on the base technique, the market is divided into x-ray crystallography, nuclear magnetic resonance, surface plasmon resonance and other screening techniques. On the basis of service, the market is segmented into library screening, fragment screening and fragment optimization. Based on the end users, the market is divided into hospitals, industry players and non-industry players. Based on region, the market is studied across North America, Asia-Pacific, Europe, and LAMEA. Among that Europe held the largest share of the market, followed by America and Asia Pacific. On the other hand, North America is expected to dominate the market during the analysis of forecast period.

Competitive Landscape

Some of The Key Players in The Fragment-Based Drug Discovery Market:

  • 2bind
  • Charles River Laboratories
  • ChemAxon
  • ComInnex
  • ChemDiv
  • Creative Biolabs
  • Creative Biostructure
  • CRELUX
  • Domainex
  • Evotec
  • Red Glead Discovery
  • SARomics Biostructures
  • Shanghai ChemPartner
  • Sygnature Discovery
  • Vernalis
  • Other Prominent Players

The Fragment-Based Drug Discovery Market Report Scope

Report Attribute Specifications
Growth Rate CAGR CAGR of 11.0 % from 2023 to 2031
Quantitative Units Representation of revenue in US$ Million and CAGR from 2023 to 2031
Historic Year 2019 to 2022
Forecast Year 2023-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Technique, By Service, By End Users
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia
Competitive Landscape 2bind, Charles River Laboratories, ChemAxon, ComInnex, ChemDiv, Creative Biolabs, Creative Biostructure, CRELUX, Domainex, Evotec, Red Glead Discovery, SARomics Biostructures, Shanghai ChemPartner, Sygnature Discovery, and Vernalis among others
Customization Scope Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing and Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Global Fragment-based Drug Discovery Market Segmentation:

Global Fragment-based Drug Discovery Market Revenue (US$ Mn) by Technique

  • X-ray Crystallography
  • Nuclear Magnetic Resonance
  • Surface Plasmon Resonance
  • Biolayer Interferometry
  • DSF Assay
  • Mass Spectrometry (MS) 
  • Capillary Electrophoresis (CE)
  • Fluorescence Polarization (FP)
  • Other Screening Techniques

 

Global Fragment-based Drug Discovery Market Revenue (US$ Mn) Based on Service

  • Library Screening
  • Fragment Screening
  • Fragment Optimization

Global Fragment-based Drug Discovery Market Revenue (US$ Mn) Based on End Users

  • Hospitals
  • Industry Players
  • Non-industry Players

Global Fragment-based Drug Discovery Market Revenue (US$ Mn) Based on Region

Europe Fragment-based Drug Discovery Market Revenue (US$ Mn) by Country

  • U.K.
  • Germany
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe

North America Fragment-based Drug Discovery Market Revenue (US$ Mn) by Country

  • U.S.
  • Canada

Asia Pacific Fragment-based Drug Discovery Market Revenue (US$ Mn) by Country

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America Fragment-based Drug Discovery Market Revenue (US$ Mn) by Country

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa Fragment-based Drug Discovery Market Revenue (US$ Mn) by Country

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

The Fragment-Based Drug Discovery Market is expected to grow at an 11.0 % CAGR during the forecast period for 2023-2031.

2bind, Charles River Laboratories, ChemAxon, ComInnex, ChemDiv, Creative Biolabs, Creative Biostructure, CRELUX, Domainex, Evotec, Red Glead Discovery
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