Fragment Based Drug Discovery Market Size, Share and Trends Analysis 2026 to 2035

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Fragment based Drug Discovery Market Segmentation :

Fragment based Drug Discovery Market, By Component-

  • Biophysical Techniques
    • NMR Spectroscopy
    • Differential Scanning Fluorimetry (DSF) Assay
    • Fluorescence Polarization
    • Isothermal Titration Calorimetry
    • X-ray Crystallography
    • Surface Plasmon Resonance (SPR)
    • Bilayer Interferometry
    • Mass Spectrometry (MS)
    • Capillary Electrophoresis
    • Weak Affinity Chromatography (WAC - HPLCUV/MS)
    • Other assays (biochemical)
  • Non-biophysical Techniques

Fragment based Drug Discovery Market, By Application-

  • Oncology
  • Central Nervous System (CNS) Disorders
  • Infectious Diseases
  • Cardiovascular Diseases
  • Metabolic Disorders
  • Inflammation & Autoimmune Diseases

Fragment based Drug Discovery Market, Based on End Users-

  • Academic & Research Institutions
  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organizations (CROs)
  • Others

Fragment based Drug Discovery Market, Based on Region-

  • North America-
    • The US
    • Canada
  • Europe-
    • Germany
    • The UK
    • France
    • Italy
    • Spain
    • Rest of Europe
  • Asia-Pacific-
    • China
    • Japan
    • India
    • South Korea
    • South East Asia
    • Rest of Asia Pacific
  • Latin America-
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
  •  Middle East & Africa-
    • GCC Countries
    • South Africa
    • Rest of Middle East and Africa

Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global Fragment-Based Drug Discovery Market Snapshot

Chapter 4. Global Fragment-Based Drug Discovery Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Porter’s Five Forces Analysis
4.7. Incremental Opportunity Analysis (US$ Mn), 2026–2035
4.8. Global Fragment-Based Drug Discovery Market Penetration & Growth Prospect Mapping (US$ Mn), 2025–2035
4.9. Competitive Landscape & Market Share Analysis, By Key Player (2025)
4.10. Use/Impact of AI on Fragment-Based Drug Discovery Industry Trends

Chapter 5. Fragment-Based Drug Discovery Market Segmentation 1: By Component/Technique, Estimates & Trend Analysis
5.1. Market Share by Component/Technique, 2025 & 2035
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2035 for the following Component/Technique:

5.2.1. Biophysical Techniques

5.2.1.1. Nuclear Magnetic Resonance (NMR) Spectroscopy
5.2.1.2. X-ray Crystallography
5.2.1.3. Surface Plasmon Resonance (SPR)
5.2.1.4. Isothermal Titration Calorimetry (ITC)
5.2.1.5. Mass Spectrometry (MS)
5.2.1.6. Differential Scanning Fluorimetry (DSF) Assay
5.2.1.7. Bilayer Interferometry
5.2.1.8. Capillary Electrophoresis
5.2.1.9. Other Biophysical Assays
5.2.2. Non-Biophysical Techniques

Chapter 6. Fragment-Based Drug Discovery Market Segmentation 2: By Service Type, Estimates & Trend Analysis
6.1. Market Share by Service Type, 2025 & 2035
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2035 for the following Service Type:

6.2.1. Fragment Screening
6.2.2. Fragment Optimization
6.2.3. Fragment Library Design & Synthesis
6.2.4. Custom Assay Development
6.2.5. Computational Fragment Modeling

Chapter 7. Fragment-Based Drug Discovery Market Segmentation 3: By Application, Estimates & Trend Analysis
7.1. Market Share by Application, 2025 & 2035
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2035 for the following Application:

7.2.1. Oncology
7.2.2. Central Nervous System (CNS) Disorders
7.2.3. Infectious Diseases
7.2.4. Cardiovascular Diseases
7.2.5. Metabolic Disorders
7.2.6. Autoimmune and Inflammation Diseases
7.2.7. Rare & Genetic Disorders

Chapter 8. Fragment-Based Drug Discovery Market Segmentation 4: By End-User, Estimates & Trend Analysis
8.1. Market Share by End-User, 2025 & 2035
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2035 for the following End-User:

8.2.1. Academic & Research Institutions
8.2.2. Pharmaceutical & Biotechnology Companies
8.2.3. Contract Research Organizations (CROs)

Chapter 9. Fragment-Based Drug Discovery Market Segmentation 5: Regional Estimates & Trend Analysis
9.1. Global Fragment-Based Drug Discovery Market Regional Snapshot, 2025 & 2035

9.2. North America

9.2.1. North America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Country, 2022–2035

9.2.1.1. United States
9.2.1.2. Canada

9.2.2. North America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Component/Technique, 2022–2035
9.2.3. North America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Service Type, 2022–2035
9.2.4. North America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Application, 2022–2035
9.2.5. North America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2022–2035

9.3. Europe

9.3.1. Europe Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Country, 2022–2035

9.3.1.1. Germany
9.3.1.2. United Kingdom
9.3.1.3. France
9.3.1.4. Italy
9.3.1.5. Spain
9.3.1.6. Rest of Europe

9.3.2. Europe Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Component/Technique, 2022–2035
9.3.3. Europe Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Service Type, 2022–2035
9.3.4. Europe Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Application, 2022–2035
9.3.5. Europe Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2022–2035

9.4. Asia Pacific

9.4.1. Asia Pacific Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Country, 2022–2035

9.4.1.1. China
9.4.1.2. Japan
9.4.1.3. India
9.4.1.4. South Korea
9.4.1.5. Southeast Asia
9.4.1.6. Rest of Asia Pacific

9.4.2. Asia Pacific Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Component/Technique, 2022–2035
9.4.3. Asia Pacific Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Service Type, 2022–2035
9.4.4. Asia Pacific Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Application, 2022–2035
9.4.5. Asia Pacific Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2022–2035

9.5. Latin America

9.5.1. Latin America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Country, 2022–2035

9.5.1.1. Brazil
9.5.1.2. Mexico
9.5.1.3. Rest of Latin America

9.5.2. Latin America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Component/Technique, 2022–2035
9.5.3. Latin America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Service Type, 2022–2035
9.5.4. Latin America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Application, 2022–2035
9.5.5. Latin America Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2022–2035

9.6. Middle East & Africa

9.6.1. Middle East & Africa Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Country, 2022–2035

9.6.1.1. GCC Countries
9.6.1.2. South Africa
9.6.1.3. Rest of Middle East & Africa

9.6.2. Middle East & Africa Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Component/Technique, 2022–2035
9.6.3. Middle East & Africa Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Service Type, 2022–2035
9.6.4. Middle East & Africa Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by Application, 2022–2035
9.6.5. Middle East & Africa Fragment-Based Drug Discovery Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2022–2035

Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles

10.2.1 2bind
10.2.2 Charles River Laboratories
10.2.3 ChemAxon
10.2.4 ComInnex
10.2.5 ChemDiv
10.2.6 Creative Biolabs
10.2.7 Creative Biostructure
10.2.8 CRELUX
10.2.9 Domainex
10.2.10 Evotec
10.2.11 Red Glead Discovery
10.2.12 SARomics Biostructures
10.2.13 Shanghai ChemPartner
10.2.14 Sygnature Discovery
10.2.15 Vernalis
10.2.16 Other Prominent Players

Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

Fragment-Based Drug Discovery Market is expected to grow at an 13.2% CAGR during the forecast period for 2026 to 2035.

2bind, Charles River Laboratories, ChemAxon, ComInnex, ChemDiv, Creative Biolabs, Creative Biostructure, CRELUX, Domainex, Evotec, Red Glead Discovery, SARomics Biostructures, Shanghai ChemPartner, Sygnature Discovery, and Vernalis Others

Fragment Based Drug Discovery Market Size is valued at USD 1.38 Billion in 2025 and is predicted to reach USD 4.53 Billion by the year 2035

Component, Application and End Users are the key segments of the Fragment Based Drug Discovery Market.

North America region is leading the Fragment Based Drug Discovery Market.

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