Endothelial Dysfunction Market Size is valued at USD 1.84 Bn in 2022 and is predicted to reach USD 2.63 Bn by the year 2031 at a 4.1% CAGR during the forecast period for 2023-2031.
Endothelial dysfunction is a condition characterised by impaired or compromised functioning of the inner lining of blood vessels, the endothelium. The endothelium is essential for sustaining vascular health and regulating multiple physiological processes.
The growth of the endothelial dysfunction market is being driven by several reasons that highlight the vital importance of vascular health in the prevention of cardiovascular diseases. These forces reflect an increasing understanding of the impact of endothelium dysfunction on general well-being and the need to mitigate associated hazards.
The market's expansion is being driven by rising rates of cardiovascular disease, particularly as the population ages and becomes more vulnerable. Unhealthy lifestyle choices, obesity, and diabetes epidemics contribute to the demand for endothelial dysfunction therapies. Targeted medicines have been developed as a result of advances in medical research and clinical understanding. Early intervention, personalized therapy, and new treatment options drive the industry forward. Awareness campaigns, increased access to healthcare, and government measures all play important roles in altering the market landscape. The pharmaceutical and biotechnology industries are investing in research & and development, which will result in innovation.
The Endothelial Dysfunction market has been segmented based on cause, test type, and end-user. The market is segmented as hypertension, diabetes, hypercholesterolemia, Baches's disease, obesity, and others based on the cause. The test type segment includes invasive tests and non-invasive tests. The end-user segment includes hospitals, ambulatory surgical centers, speciality clinics, and others.
Endothelial dysfunction market share was higher in the invasive testing segment. Endothelial dysfunction is typically diagnosed via invasive diagnostics during coronary angiography. Vasoreactivity testing is the main focus of endothelial dysfunction testing. Vasoreactivity testing is the most clinically evident vascular endothelium function. Hence invasive studies are performed. Invasive tests are often performed using two techniques: intracoronary and intrabrachial vasoactive agent infusions. These methods are still regarded as the gold standard for detecting endothelium dysfunction early. These invasive procedures have been described in several cardiometabolic disease states linked to future atherosclerosis and other negative effects.
As a silent killer, hypertension causes deadly cardiovascular illnesses. Hypertension is well acknowledged as one of the most common disorders among the elderly. The prevalence of hypertension rises dramatically with age. Ageing and high blood pressure are independent predictors of cardiovascular and cerebrovascular outcomes. Aging is linked to changes in vascular structure and function by various mechanisms, including oxidative stress, cell senescence, and inflammation. Furthermore, hypertension hastens ageing-related changes in vascular structure and function, particularly endothelial function.
Geographically, the market for endothelial dysfunction products in North America and Europe is currently the leading market due to strong engagement in research and development, modern medical facilities, and widespread awareness of cardiovascular illnesses and other related conditions. The absence of government participation and funding for research and development has hampered emerging and developing economies' growth and revenue share. With a significant increase in cardiovascular and diabetes cases in Asia-Pacific and Middle Eastern countries in the coming years, the endothelial dysfunction market is expected to grow in these regions over the next 5-7 years.
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Report Attribute |
Specifications |
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Market Size Value In 2022 |
USD 1.84 Bn |
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Revenue Forecast In 2031 |
USD 2.63 Bn |
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Growth Rate CAGR |
CAGR of 4.1% from 2023 to 2031 |
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Quantitative Units |
Representation of revenue in US$ Bn and CAGR from 2023 to 2031 |
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Historic Year |
2019 to 2022 |
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Forecast Year |
2023-2031 |
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Report Coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
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Segments Covered |
By Cause, Test Type, End-User |
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Regional Scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
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Country Scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;France; Italy; Spain; South Korea; South East Asia |
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Competitive Landscape |
ZOLL Medical Corp, Sphingo Tec GmbH, Lawrence Berkeley National Laboratory, The Polymath Co, Endothelix Inc, Perimed AB, SMART Medical Ltd, Everist Health Inc, Alam Medical SaRi, and Medizinische Messtechnik GmbH. |
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Customization Scope |
Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape. |
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Pricing And Available Payment Methods |
Explore pricing alternatives that are customized to your particular study requirements. |
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Endothelial Dysfunction Market Snapshot
Chapter 4. Global Endothelial Dysfunction Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis
Chapter 5. Market Segmentation 1: By Cause Estimates & Trend Analysis
5.1. By Cause, & Market Share, 2020 & 2031
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2031 for the following By Cause:
5.2.1. Hypertension
5.2.2. Diabetes
5.2.3. Hypercholestrolaemia
5.2.4. Bechet’s Disease
5.2.5. Obesity
5.2.6. Others
Chapter 6. Market Segmentation 2: By Test Type Estimates & Trend Analysis
6.1. By Test Type & Market Share, 2020 & 2031
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2031 for the following By Test Type:
6.2.1. Invasive Tests
6.2.2. Non-Invasive Tests
6.2.2.1. Flow Mediated Dilatory
6.2.2.2. Peripheral Arterial Tonometry (PAT)
6.2.2.3. Venous Occlusion Pletismography
6.2.2.4. Circulating Markers
6.2.2.5. Others
Chapter 7. Market Segmentation 3: By End User Estimates & Trend Analysis
7.1. By End User & Market Share, 2020 & 2031
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2031 for the following By End User:
7.2.1. Hospitals
7.2.2. Ambulatory Surgery Centers
7.2.3. Specialty Clinics
7.2.4. Others
Chapter 8. Endothelial Dysfunction Market Segmentation 4: Regional Estimates & Trend Analysis
8.1. North America
8.1.1. North America Endothelial Dysfunction Market revenue (US$ Million) estimates and forecasts By Cause, 2019-2031
8.1.2. North America Endothelial Dysfunction Market revenue (US$ Million) estimates and forecasts By Test Type, 2019-2031
8.1.3. North America Endothelial Dysfunction Market revenue (US$ Million) estimates and forecasts By End User, 2019-2031
8.1.4. North America Endothelial Dysfunction Market revenue (US$ Million) estimates and forecasts by country, 2019-2031
8.2. Europe
8.2.1. Europe Endothelial Dysfunction Market revenue (US$ Million) By Cause, 2019-2031
8.2.2. Europe Endothelial Dysfunction Market revenue (US$ Million) By Test Type, 2019-2031
8.2.3. Europe Endothelial Dysfunction Market revenue (US$ Million) By End User, 2019-2031
8.2.4. Europe Endothelial Dysfunction Market revenue (US$ Million) by country, 2019-2031
8.3. Asia Pacific
8.3.1. Asia Pacific Endothelial Dysfunction Market revenue (US$ Million) By Cause, 2019-2031
8.3.2. Asia Pacific Endothelial Dysfunction Market revenue (US$ Million) By Test Type, 2019-2031
8.3.3. Asia Pacific Endothelial Dysfunction Market revenue (US$ Million) By End User, 2019-2031
8.3.4. Asia Pacific Endothelial Dysfunction Market revenue (US$ Million) by country, 2019-2031
8.4. Latin America
8.4.1. Latin America Endothelial Dysfunction Market revenue (US$ Million) By Cause, (US$ Million) 2019-2031
8.4.2. Latin America Endothelial Dysfunction Market revenue (US$ Million) By Test Type, (US$ Million) 2019-2031
8.4.3. Latin America Endothelial Dysfunction Market revenue (US$ Million) By End User, (US$ Million) 2019-2031
8.4.4. Latin America Endothelial Dysfunction Market revenue (US$ Million) by country, 2019-2031
8.5. Middle East & Africa
8.5.1. Middle East & Africa Endothelial Dysfunction Market revenue (US$ Million) By Cause, (US$ Million) 2019-2031
8.5.2. Middle East & Africa Endothelial Dysfunction Market revenue (US$ Million) By Test Type, (US$ Million) 2019-2031
8.5.3. Middle East & Africa Endothelial Dysfunction Market revenue (US$ Million) By End User, (US$ Million) 2019-2031
8.5.4. Middle East & Africa Endothelial Dysfunction Market revenue (US$ Million) by country, 2019-2031
Chapter 9. Competitive Landscape
9.1. Major Mergers and Acquisitions/Strategic Alliances
9.2. Company Profiles
9.2.1. ZOLL Medical Corp,
9.2.2. Sphingo Tec GmbH,
9.2.3. Lawrence Berkeley National Laboratory,
9.2.4. The Polymath Co,
9.2.5. Endothelix Inc,
9.2.6. Perimed AB,
9.2.7. SMART Medical Ltd,
9.2.8. Everist Health Inc,
9.2.9. Alam Medical SaRl,
9.2.10. Medizinische Messtechnik GmbH
Endothelial Dysfunction Market By Cause-
Endothelial Dysfunction Market By Test Type-
Endothelial Dysfunction Market By End-User-
Endothelial Dysfunction Market By Region-
North America-
Europe-
Asia-Pacific-
Latin America-
Middle East & Africa-
InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.
Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.
Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.
Secondary research
The secondary research sources that are typically mentioned to include, but are not limited to:
The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista
Primary Research:
Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies
The contributors who typically take part in such a course include, but are not limited to:
Data Modeling and Analysis:
In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.
The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.
To know more about the research methodology used for this study, kindly contact us/click here.
