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Monolith Chromatography Columns Market

Monolith Chromatography Columns Market Size, Share & Trends Analysis Distribution By Monolithic Columns (Silica-Based, Polymer-Based, Hybrid Monolithic Column), Technology (High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Liquid Chromatography (LC), Capillary Electrochromatography (CEC), Supercritical Fluid Chromatography), End-Users (Pharmaceutical Biotechnology Companies, Food &Amp; Beverage Manufacturers, Diagnostics) And Segment Forecasts, 2024-2031

Report ID : 2558 | Published : 2024-07-03 | Pages: 180 | Format: PDF/EXCEL

Monolith Chromatography Columns Market Size is valued at USD 118.7 Mn in 2023 and is predicted to reach USD 203.5 Mn by the year 2031 at an 7.29% CAGR during the forecast period for 2024-2031.

Monolith Chromatography Columns Market info

Monolith chromatography columns represent a specialized advancement in liquid chromatography, particularly in techniques like high-performance liquid chromatography (HPLC). Unlike traditional packed columns that consist of small beads of stationary phase material, monolith columns feature a singular, porous rod-like structure with interconnected channels and pores. This unique design offers several distinct advantages over packed columns.

Monolith columns offer higher permeability and lower backpressure, enabling faster separations at higher flow rates, boosting throughput in chromatographic analyses. Their larger surface area and enhanced binding capacity improve resolution and loading efficiency, ideal for separating complex mixtures. Additionally, monolith columns are less prone to clogging from complex sample matrices due to their interconnected pore structure. This feature ensures consistent performance over extended periods, making them reliable for both routine analyses and rigorous purification processes.

The global monolith chromatography columns market is experiencing growth driven by the rising need for faster and more efficient liquid chromatography techniques. This demand is primarily fueled by the rapid development of new drugs, biotherapeutics, and other high-value products. Monolith columns are particularly favored for their capability to achieve high-throughput separations and effectively handle complex samples, making them highly attractive in these critical application areas.

Competitive Landscape

Some of the Key Players in Monolith Chromatography Columns Market:

  • Merck Millipore
  • Thermo Fisher Scientific (Dionex)
  • Danaher (Phenomenex)
  • Sartorius (Bia separations)
  • Agilent Technologies
  • Bio-Rad Laboratories
  • Showa Denko K. K.
  • GL Sciences Inc.
  • Metrohm AG
  • Waters Corporation

Market Segmentation:

The Monolith Chromatography Columns market is segmented by Monolithic Columns, technology, and end user. By Monolithic Columns the market is segmented into Silica-based, polymer-based, hybrid monolithic column. By technology market is categorized into (High-performance liquid chromatography (HPLC), Gas chromatography (GC), Liquid chromatography (LC), Capillary electrochromatography (CEC), Supercritical fluid chromatography. By end user the market is categorized Pharmaceutical Biotechnology Companies, Food &amp, Beverage Manufacturers, Diagnostics.

Silica-based Monolith Chromatography Column is Expected to Drive the Monolith Chromatography Columns Market

The silica-based monolith chromatography column segment is driving growth in the global market for several reasons. These columns offer superior performance over traditional packed columns with higher permeability and lower backpressure, enabling faster separations at higher flow rates. Their larger surface area and binding capacity enhance resolution and loading capacity, while the monolithic structure reduces susceptibility to clogging from complex sample matrices. Continuous technological advancements have further improved separation efficiency and peak symmetry. Manufacturers like Waters Corporation have invested significantly in optimizing these technologies, expanding their applications and performance capabilities. This aligns well with market demands from pharmaceutical, biotechnology, and other industries seeking faster and more efficient liquid chromatography techniques to support the rapid development of new drugs, biotherapeutics, and high-value products.

The Oncology disorder is Growing at the Highest Rate in the Monolith Chromatography Columns Market.

The High-performance liquid chromatography (HPLC) segment is witnessing rapid growth within the chromatography market driven by several key factors. Primarily, there is increasing demand from the pharmaceutical and biotechnology industries where HPLC plays a crucial role in drug development, quality control, and the characterization of drug candidates and biotherapeutics. Technological advancements in HPLC column technologies, particularly the development of silica-based monolith columns, have enhanced the efficiency of separations, offering benefits such as high permeability, increased loading capacity, and capability to handle complex samples. Additionally, HPLC is gaining traction in diverse sectors including academic research, clinical diagnostics, food testing, and environmental analysis, driven by rising government funding and increased R&D spending across these areas, further fueling market expansion.

Regionally, North America Led the Monolith Chromatography Columns Market

North America stands out as the leading region in the global monolith chromatography columns market for several compelling reasons. With the largest market size in the overall chromatography columns market as of 2023, North America benefits from a robust pharmaceutical industry that extensively employs HPLC and monolith columns for drug development, quality control, and characterization processes. Key players in chromatography, such as Waters Corporation, which manufactures silica-based monolith columns, are headquartered in North America, contributing to the region's leadership in innovation and technological advancement.

Monolith Chromatography Columns Market Report Scope

Report Attribute

Specifications

Market Size Value In 2022

USD 118.7 Mn

Revenue Forecast In 2031

USD 203.5 Mn

Growth Rate CAGR

CAGR of 7.29 % from 2024 to 2031

Quantitative Units

Representation of revenue in US$ Bn and CAGR from 2024 to 2031

Historic Year

2019 to 2023

Forecast Year

2024-2031

Report Coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments Covered

By Monolithic Columns, By Technology, By End-Users and By Region

Regional Scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country Scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; Southeast Asia; South Korea; Southeast Asia

Competitive Landscape

Merck Millipore, Thermo Fisher Scientific (Dionex), Danaher (Phenomenex), Sartorius (Bia separations), Agilent Technologies, Bio-Rad Laboratories, Showa Denko K. K., GL Sciences Inc., Metrohm AG, Waters Corporation

Customization Scope

Free customization report with the procurement of the report, Modifications to the regional and segment scope. Geographic competitive landscape.                     

Pricing and Available Payment Methods

Explore pricing alternatives that are customized to your particular study requirements.

Chapter 1. Methodology and Scope

1.1. Research Methodology

1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global Monolith Chromatography Columns Market Snapshot

Chapter 4. Global Monolith Chromatography Columns Market Variables, Trends & Scope

4.1. Market Segmentation & Scope

4.2. Drivers

4.3. Challenges

4.4. Trends

4.5. Investment and Funding Analysis

4.6. Industry Analysis – Porter’s Five Forces Analysis

4.7. Competitive Landscape & Market Share Analysis

4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: By Monolithic Columns Estimates & Trend Analysis

5.1. By Monolithic Columns & Market Share, 2020 & 2031

5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2031 for the following By Monolithic Columns:

5.2.1. Silica-based

5.2.2. polymer-based

5.2.3. hybrid monolithic column

Chapter 6. Market Segmentation 2: By Technology Estimates & Trend Analysis

6.1. By Technology & Market Share, 2020& 2031

6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2031 for the following By Technology:

6.2.1. HPLC

6.2.2. GC

6.2.3. LC

6.2.4. Capillary electrochromatography (CEC)

6.2.5. Supercritical fluid chromatography

Chapter 7. Market Segmentation 3: By End-Users Estimates & Trend Analysis

7.1. By End-Users & Market Share, 2020& 2031

7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2020 to 2031 for the following By End-Users:

7.2.1. Pharmaceutical Biotechnology Companies

7.2.2. Food & Beverage Manufacturers

7.2.3. Diagnostics

Chapter 8. Monolith Chromatography Columns Market Segmentation 4: Regional Estimates & Trend Analysis

8.1. North America

8.1.1. North America Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts By Monolithic Columns, 2019-2031

8.1.2. North America Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts By Technology, 2019-2031

8.1.3. North America Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts by End-Users, 2019-2031

8.1.4. North America Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts by country, 2019-2031

8.2. Europe

8.2.1. Europe Monolith Chromatography Columns Market revenue (US$ Million) By Monolithic Columns, 2019-2031

8.2.2. Europe Monolith Chromatography Columns Market revenue (US$ Million) By Technology, 2019-2031

8.2.3. Europe Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts by End-Users, 2019-2031

8.2.4. Europe Monolith Chromatography Columns Market revenue (US$ Million) by country, 2019-2031

8.3. Asia Pacific

8.3.1. Asia Pacific Monolith Chromatography Columns Market revenue (US$ Million) By Monolithic Columns, 2019-2031

8.3.2. Asia Pacific Monolith Chromatography Columns Market revenue (US$ Million) By Technology, 2019-2031

8.3.3. Asia Pacific Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts by End-Users, 2019-2031

8.3.4. Asia Pacific Monolith Chromatography Columns Market revenue (US$ Million) by country, 2019-2031

8.4. Latin America

8.4.1. Latin America Monolith Chromatography Columns Market revenue (US$ Million) By Monolithic Columns, 2019-2031

8.4.2. Latin America Monolith Chromatography Columns Market revenue (US$ Million) By Technology, 2019-2031

8.4.3. Latin America Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts by End-Users, 2019-2031

8.4.4. Latin America Monolith Chromatography Columns Market revenue (US$ Million) by country, 2019-2031

8.5. Middle East & Africa

8.5.1. Middle East & Africa Monolith Chromatography Columns Market revenue (US$ Million) By Monolithic Columns, 2019-2031

8.5.2. Middle East & Africa Monolith Chromatography Columns Market revenue (US$ Million) By Technology, 2019-2031

8.5.3. Middle East & Africa Monolith Chromatography Columns Market revenue (US$ Million) estimates and forecasts by End-Users, 2019-2031

8.5.4. Middle East & Africa Monolith Chromatography Columns Market revenue (US$ Million) by country, 2019-2031

Chapter 9. Competitive Landscape

9.1. Major Mergers and Acquisitions/Strategic Alliances

9.2. Company Profiles

9.2.1. Merck Millipore

9.2.2. Thermo Fisher Scientific (Dionex)

9.2.3. Danaher (Phenomenex)

9.2.4. Sartorius (Bia separations)

9.2.5. Agilent Technologies

9.2.6. Bio-Rad Laboratories

9.2.7. Showa Denko K. K.

9.2.8. GL Sciences Inc.

9.2.9. Other Prominent Players

Segmentation of Monolith Chromatography Columns Market -

Monolith Chromatography Columns Market by Monolithic Columns -

  • Silica-based
  • polymer-based
  • hybrid monolithic column

Monolith Chromatography Columns Market seg

Monolith Chromatography Columns Market by Technology          -

  • High-performance liquid chromatography (HPLC)
  • Gas chromatography (GC)
  • Liquid chromatography (LC)
  • Capillary electrochromatography (CEC)
  • Supercritical fluid chromatography

 Monolith Chromatography Columns Market by End-Users -

  • Pharmaceutical Biotechnology Companies
  • Food & Beverage Manufacturers
  • Diagnostics            

Monolith Chromatography Columns Market by Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

How big is the Monolith Chromatography Columns Market Size?

Monolith Chromatography Columns Market is predicted to develop at an 7.29% CAGR during the forecast period for 2024-2031.

Sartorius (Bia separations), Agilent Technologies, Bio-Rad Laboratories, Showa Denko K. K., GL Sciences Inc., Metrohm AG, Waters Corporation

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