KRAS Inhibitors Market Size is valued at USD 1010.91 Mn in 2023 and is predicted to reach USD 157.68 Mn by the year 2031 at a 5.77% CAGR during the forecast period for 2024-2031.
Kirsten rat sarcoma viral oncogene homolog inhibitor genes encode a protein in many cell signalling pathways. Several cancers, including lung, colorectal, and pancreatic cancers, often include mutations in the KRAS gene. Carcinogenesis, or the unchecked growth of cells, can result from these alterations. A group of medications known as KRAS inhibitors has been developed to block the signalling pathways connected with the mutant KRAS protein. By blocking the aberrant cellular signalling brought on by the mutant KRAS gene, these medications hope to decrease the rate of cancer cell proliferation and metastasis. Kirsten rat sarcoma has become more necessary due to the rising incidence of lung cancer (KRAS). Recent advances in pharmaceutical research and the creation of novel anti-cancer drugs have contributed to the growth of the Kirsten rat sarcoma (KRAS) industry. These variables are expected to drive the market's expansion in the time allotted. Furthermore, Innovations in structure-based drug design and identifying new inhibitors have paved the way for creating potent KRAS inhibitors, which should lead to further market expansion.
However, the market growth is hampered by the strict regulatory criteria for the safety and health of the KRAS inhibitors market and the product's inability to prevent fog in environments with dramatic temperature fluctuations or high humidity KRAS inhibitors, a potential obstacle to market expansion could be the impatience with which the benefits of Kirsten rat sarcoma (KRAS) research are acknowledged. It is costly to pay for diagnostic tests performed in hospitals and labs. Critical investigations are still in progress. All of these factors have the potential to impede the market's growth. The pandemic of COVID-19 has highlighted the urgent need to hasten the creation of cancer care technology and encourage worldwide cooperation to tackle global health issues. Therefore, some of these challenges are anticipated to become more handleable and ultimately overcome in a post-COVID environment.
Competitive Landscape
Some Major Key Players In The KRAS Inhibitors Market:
- Amgen
- Boehringer Ingelheim
- BridgeBio Pharma
- Erasca
- Innovent Biologics, Inc.
- Incyte
- Mirati Therapeutics
- Novartis
- Jemincare
- Cardiff Oncology, Inc.
- Roche
- Genentech
- Verastem Oncology
- Revolution Medicines
- Immuneering Corporation
- Jacobio Pharmaceuticals
- Deciphera Pharmaceuticals
- Elicio Therapeutics
- InventisBio
- Gritstone Bio
- D3 Bio
- Others
Market Segmentation:
The KRAS inhibitors market is segmented based on cancer type and end-use. According to cancer type, the market is segmented into lung cancer, pancreatic cancer, colorectal cancer, and others. By end-use, the market is segmented into clinic laboratories, cancer diagnostic centres, hospitals, cancer research institutes, academic institutions, and others.
Based On The Cancer Type, The Lung Cancer KRAS Inhibitors Market Segment Is Accounted As A Major Contributor To The KRAS Inhibitors Market.
The Lung cancer KRAS inhibitors market is expected to hold a major global market share in 2023. Lung cancer patients have a disproportionately high number of KRAS mutations, which presents a substantial opportunity for the KRAS inhibitor market. Many lung cancer patients may find successful therapy choices if these mutations are targeted. There is a big, unfulfilled medical need for effective treatments for lung cancer, especially non-small cell lung cancer (NSCLC), which is a difficult illness to treat. There is a current medical need to treat KRAS-mutant lung cancer, and KRAS inhibitors provide a potential way to target these mutations precisely.
Cancer Research Institutes Segment To Witness Growth At A Rapid Rate.
Cancer research institutes make up the bulk of KRAS inhibitors because of the growing number of collaborations between research institutions and biotech businesses and the expansion of clinical research, especially in countries like the US, Germany, the UK, China, and India.
In The Region, The North American KRAS Inhibitors Market Holds A Significant Revenue Share.
The North American KRAS inhibitors market is expected to register the maximum market share in revenue in the near future. It can be attributed to the demand for targeted treatments in oncology, improvements in healthcare infrastructure, the frequency of KRAS mutations in different cancer types, and the pace of drug discovery and development, all potential drivers of market expansion in this field. In addition, Asia Pacific is estimated to grow rapidly in the global KRAS inhibitors market because the ageing population and the rising desire for effective treatment through personalized medicine are expected to propel the growth of regional markets in the next year. The region's market is anticipated to experience expansion due to the increasing emphasis on biotechnology and its technological advancements.
Recent Developments:
- In October 2022, At the AACR annual meeting, Novartis presented encouraging clinical results for JDQ443, an experimental selective, covalent, and orally accessible KRASG12C inhibitor. A poster on Wednesday, April 13, and Cancer Discovery1 provide detailed information about JDQ443's discovery. JDQ443, discovered at Novartis, showed anti-tumor activity, high systemic exposure at its necessory dose, and a favorable safety profile in patients with KRAS G12C-mutated solid tumors in Phase Ib of the KontRASt-01 study (NCT04699188)2. In an oral session, the late-breaking abstract data will be presented.
- In September 2023, Amgen reported promising results from a specific part of the CodeBreaK 101 clinical trial, which is a Phase 1b research investigating the effectiveness of LUMAKRAS® (sotorasib) in combination with carboplatin and pemetrexed for treating adult patients with advanced non-small cell lung cancer (NSCLC) that contains a specific genetic mutation called KRAS G12C. The aforementioned findings were presented orally at the 2023 World Conference on Lung Cancer (WCLC), organized by the IASLC.
KRAS Inhibitors Market Report Scope
|
Report Attribute |
Specifications |
|
Market Size Value In 2023 |
USD 101.91 Mn |
|
Revenue Forecast In 2031 |
USD 157.68 Mn |
|
Growth Rate CAGR |
CAGR of 5.77 % from 2024 to 2031 |
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Quantitative Units |
Representation of revenue in US$ Mn and CAGR from 2024 to 2031 |
|
Historic Year |
2019 to 2023 |
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Forecast Year |
2024-2031 |
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Report Coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
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Segments Covered |
By Cancer Type, End-User |
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Regional Scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
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Country Scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South East Asia; South Korea |
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Competitive Landscape |
Amgen, Boehringer Ingelheim, BridgeBio Pharma, Erasca, Innovent Biologics Inc., Incyte, Mirati Therapeutics, Novartis, Jemincare, Cardiff Oncology, Inc., Roche, Genentech, Verastem Oncology, Revolution Medicines, Immuneering Corporation, Jacobio Pharmaceuticals, Deciphera Pharmaceuticals, Elicio Therapeutics, InventisBio, Gritstone Bio, D3 Bio and Others |
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Customization Scope |
Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape. |
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Pricing And Available Payment Methods |
Explore pricing alternatives that are customized to your particular study requirements. |
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