Hyaluronic Acid API Market Size, Share & Trends Analysis Report By Type (Animal Tissue, Microbial Fermentation), By Application (Cosmetics, Medical, Food), By Region, And By Segment Forecasts, 2024-2031.

Report Id: 2450 Pages: 179 Last Updated: 29 April 2024 Format: PDF / PPT / Excel / Power BI
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Hyaluronic Acid API Market Size is valued at USD 501.85 Mn in 2023 and is predicted to reach USD 1,392.64 Mn by the year 2031 at a 13.77% CAGR during the forecast period for 2024-2031.

Hyaluronic Acid API Market info

Hyaluronic acid, when used as an active pharmaceutical ingredient (API), is highly esteemed for its adaptability and effectiveness in addressing various conditions that necessitate lubrication and moisture preservation. This applies to both internal applications in joints and external applications on the skin and tissues. The biocompatibility and limited adverse effects of this substance continue to fuel its increasing use in novel therapeutic and cosmetic preparations. As a result of rising incomes and better healthcare infrastructure, hyaluronic acid API products are reaching more people in developing markets. The world’s aging population is expanding at a rapid pace. The body’s natural production of hyaluronic acid declines with age, causing wrinkles to appear and skin to lose its flexibility. Hyaluronic acid active pharmaceutical ingredient demand has skyrocketed due to the increasing popularity of skin care products and dermal fillers formulated with hyaluronic acid to stave off the appearance of aging for as long as possible.

However, market growth is hampered by the expensive hyaluronic acid API production costs and the availability of alternative medicine. Additionally, hyaluronic acid API market potential may arise as a result of healthcare amenity price increases. In addition, modern biotechnological developments have reduced production costs and increased the efficiency of hyaluronic acid synthesis. More and more people are learning about the importance of skincare and its advantages, which has boosted the demand for the hyaluronic acid API market.

Competitive Landscape

Some Major Key Players In The Hyaluronic Acid API Market:

  • Bloomage Biotech
  • Focus Chem
  • Fufeng Group
  • AWA Biopharm
  • China Eastar Group
  • Kewpie
  • Seikagaku
  • HTL Biotechnology
  • Fidia Farmaceutici
  • Other Market Players

Market Segmentation:

The hyaluronic acid API market is segmented based on type and application. Based on type, the market is segmented into animal tissue and microbial fermentation. As per the application segment, the market is segmented into cosmetics, medical and food. 

Based On The Type, The Animal Tissue Segment Is Accounted As A Major Contributor To The Hyaluronic Acid API Market 

The animal tissue hyaluronic acid API market is expected to lead with a major global market share in 2023 because of its efficacy and great biocompatibility. Animal tissue-derived hyaluronic acid, primarily from rooster combs and bovine vitreous humor, has a molecular structure that is very similar to naturally occurring human hyaluronic acid. This is very important for uses that require biocompatibility, like lip fillers, eye surgeries, and treatments to smooth out joints. Treatments are more effective, and side effects are less likely due to the resemblance, which helps reduce the body’s immune response factor, fueling the market’s expansion.

Cosmetics Segment To Witness Growth At A Rapid Rate

The cosmetics segment is growing rapidly because of its remarkable moisturizing characteristics, which aid in maintaining skin hydration and provide a full, young look. Hyaluronic acid is highly prized in the cosmetics business. An expanding number of cosmetics, including serums, moisturizers, foundations, and lip treatments, contain hyaluronic acid API as a key ingredient to combat the signs of aging and promote healthy skin. The market for cosmetics based on hyaluronic acid API has been further boosted by the growing awareness of the benefits of using clean, scientifically-backed skincare components.

In The Region, The North American Hyaluronic Acid API Market Holds A Significant Revenue Share.

The North American hyaluronic acid API market is expected to record the maximum market revenue share in the near future. Due to a rising focus on skincare and anti-aging products and a large concentration of well-known cosmetics and pharmaceutical brands. In addition, Europe is estimated to grow rapidly in the global hyaluronic acid API market because the availability of high-quality hyaluronic acid API is assured by the region’s strong regulatory framework for product approvals and safety regulations, an increase in the presence of key market competitors, and the rising cost of healthcare in the area.

Recent Developments:

  • In Dec 2023, Bloomage unveiled its Bloomsurfact EncapCare RP emulsion solution. This solution effectively rejuvenates skin and fights against ageing. The EncapCare RP is a great alternative for sensitive skin because it uses Bloomage's proprietary component dispersion technology with Bloomsurfact Sodium Surfactin to guarantee high bioavailability, stability, and reduced irritation.
  • In Oct 2021, HTL Biotechnology substantially enhanced its production capacity for hyaluronic acid through fermentation at its facility in Javené, France. According to HTL, their $58 million investment has positioned them as the leading global manufacturer of pharmaceutical-grade hyaluronic acid. Orthopedists employ hyaluronic acid injections to alleviate joint pain, while cosmetic surgeons utilize them to address sunken areas of the face, among other uses.

Hyaluronic Acid API Market Report Scope

Report Attribute Specifications
Market Size Value In 2023 USD 501.85 Mn
Revenue Forecast In 2031 USD 1,392.64 Mn
Growth Rate CAGR CAGR of 13.77% from 2024 to 2031
Quantitative Units Representation of revenue in US$ Mn and CAGR from 2024 to 2031
Historic Year 2019 to 2023
Forecast Year 2024-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Type And Application
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South East Asia; South Korea
Competitive Landscape Bloomage Biotech, Focus Chem, Fufeng Group, AWA Biopharm, China Eastar Group, Kewpie, Seikagaku, HTL Biotechnology, Fidia Farmaceutici and Other market players.
Customization Scope Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing And Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of Hyaluronic Acid API Market-

Hyaluronic Acid API Market By Type-

  • Animal Tissue
  • Microbial Fermentation

Hyaluronic Acid API Market seg

Hyaluronic Acid API Market By Application-

  • Cosmetics
  • Medical
  • Food

Hyaluronic Acid API Market By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

Hyaluronic Acid API Market Size is valued at USD 501.85 Mn in 2023 and is predicted to reach USD 1,392.64 Mn by the year 2031

Hyaluronic Acid API Market is expected to grow at a 13.77% CAGR during the forecast period for 2024-2031.

Focus Chem, Fufeng Group, AWA Biopharm, China Eastar Group, Kewpie, Seikagaku, HTL Biotechnology, Fidia Farmaceutici and Other market players.
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