GMP Biologics Market, Share & Trends Analysis Report, By Type (Monoclonal Antibodies, Polyclonal Antibody), By Application (Hospitals, Clinics, Others), By Region, and Segment Forecasts, 2024-2031

Report Id: 2715 Pages: 165 Last Updated: 29 August 2024 Format: PDF / PPT / Excel / Power BI
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The GMP Biologics Market Size is valued at USD 52.3 Bn in 2023 and is predicted to reach USD 153.9 Bn by the year 2031 at an 14.6% CAGR during the forecast period for 2024-2031.

GMP biologics

The term "Good Manufacturing Practice" (GMP) Biologics describes the manufacture of biologic pharmaceuticals by strict legal requirements intended to guarantee the effectiveness, safety, and quality of the final product. The World Health Organization (WHO) and other organizations have established GMP standards, which require biologic manufacturing processes to be controlled and recorded to minimize hazards like contamination and guarantee uniformity between production batches. The GMP criteria for biologics are distinct from those for other medical goods because of their unique characteristics.

For instance, The European Medicines Agency (EMA) is responsible for the evaluation and supervision of medicines within the European Union. To ensure the consistent quality and safety of medicinal products, the EMA has established detailed Good Manufacturing Practices (GMP) guidelines. These guidelines outline the specific requirements for the manufacturing, testing, and release of medicinal products, including biologics. By setting these standards, the EMA ensures that products meet stringent quality criteria, safeguarding public health across the EU. The primary factors influencing the GMP Biologics market include the increased use of biosimilars and monoclonal antibodies, technological developments in bioprocessing, and an increasing emphasis on customized treatment. Because of their great specificity and potency, monoclonal antibodies in particular are becoming more and more significant in the treatment of a wide range of diseases, including autoimmune disorders and cancer.

Competitive Landscape

Some of the Major Key Players in the GMP Biologics Market are

  • Amgen Inc.
  • Hoffmann-La Roche Ltd
  • AbbVie Inc.
  • AstraZeneca plc
  • Merck KGaA
  • Creative Diagnostics
  • Fisher Bioservices (Thermo Fisher Scientific)
  • Polpharma Biologics
  • Intertek
  • HemaCare
  • AGC
  • AstraZeneca plc
  • Merck KGaA
  • Sanofi
  • GlaxoSmithKline plc
  • Johnson & Johnson
  • Pfizer Inc.
  • Novartis AG
  • Eli Lilly and Company
  • Samsung Biologics Co. Ltd.
  • WuXi AppTec
  • Lonza Group Ltd.
  • Rentschler Biopharma SE
  • Boehringer Ingelheim International GmbH
  • Celltrion Inc
  • Catalent Inc.

Market Segmentation

The GMP Biologics Market is segmented based on the type, and application. Based on the type, the market is divided into monoclonal antibodies and polyclonal antibodies. Based on the application market is categorized into hospitals, clinics, and others.

The Monoclonal Antibodies Segment Is Expected To Have The Highest Growth Rate During The Forecast Period

Based on the monoclonal antibodies, the market segment into monoclonal antibodies and polyclonal antibodies. Among these, the monoclonal antibodies segment is expected to have the highest growth rate during the forecast period. makes them better for treating a range of illnesses, especially chronic ailments and oncology. It is anticipated that this market would remain dominant because to the continuous progress in biopharmaceutical research and the growing need for customized treatment. Because of their ability to precisely target particular antigens, monoclonal antibodies (MAbs) are extensively used in hospitals and clinical settings to improve treatment outcomes and reduce side effects. Because polyclonal antibodies may recognize many epitopes, they are important in research and diagnostics but have a limited market share in GMP biologics. They are useful in many different applications due to their broad reactivity and reduced production costs, but their market expansion is constrained when compared to highly effective and specific monoclonal antibodies.

The Hospital Segment Dominates The Market

Based on the application, the market is segmented into hospitals, clinics, and others. Among these, the hospital segment dominates the market. Among these, the hospital segment dominates the market. This is because hospitals are primary centers for advanced treatments, including those involving biologics, such as monoclonal antibodies, gene therapies, and other specialized treatments. Hospitals usually have the infrastructure and resources necessary for administering complex biological therapies, which require precise handling, storage, and administration.

North America Have The Largest Market Share During Forecast Period

North America has the largest market share during the forecast period. Due to the existence of multiple reputable biopharmaceutical businesses and a strong regulatory environment that promotes the development of biologic drugs. The region boasts a robust infrastructure, including world-class research institutions, manufacturing facilities, and supply chains, which are essential for the production and distribution of biologics.

Recent Developments:

  • In March 2024, Thermo Fisher Scientific Inc. has expanded its clinical trial network throughout Europe by opening a new ultra-cold clinical and commercial facility in the EU, which will aid in hastening the development of cutting-edge treatments. Pharma and biopharma customers can receive end-to-end assistance for high-value medicines, such as cell and gene therapies, biologics, antibodies, and vaccines, throughout the clinical supply chain from the recently established current good manufacturing practice (cGMP) facility located in Bleiswijk, Netherlands.
  • In Jan 2023, Creative Diagnostics raised its monoclonal antibody capabilities and offerings to global customers, including over 1,000 targets, carrier-free formulations, and conjugated antibodies. The company provided raw materials, antibodies, and reagents for the biotechnology industry.
  • In June 2020, HemaCare, declared that the introduction of the GMPrime cryopreserved leukopak has increased the range of GMP-compliant cellular material in its inventory. HemaCare's well-liked cryopreserved leukopak for research usage (HemaPrimeTM) now has QA review added to it since the GMP-compliant cryopreserved leukopak comes with a Certificate of Analysis that has been quality assurance (QA) evaluated.

GMP Biologics Market Report Scope

Report Attribute Specifications
Market Size Value In 2023 USD 52.3 Bn
Revenue Forecast In 2031 USD 153.9 Bn
Growth Rate CAGR CAGR of 14.6% from 2024 to 2031
Quantitative Units Representation of revenue in US$ Bn and CAGR from 2024 to 2031
Historic Year 2019 to 2023
Forecast Year 2024-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Type and Application
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South Korea; South East Asia
Competitive Landscape Amgen Inc., F. Hoffmann-La Roche Ltd, AbbVie Inc., AstraZeneca plc, Merck KGaA, Creative Diagnostics, Fisher Bioservices (Thermo Fisher Scientific), Polpharma Biologics, Intertek, HemaCare, AGC, AstraZeneca plc, Merck KGaA, Sanofi, GlaxoSmithKline plc, Johnson & Johnson, Pfizer Inc., Novartis AG, Eli Lilly and Company, Samsung Biologics Co. Ltd., WuXi AppTec, Lonza Group Ltd., Rentschler Biopharma SE, Boehringer Ingelheim International GmbH, Celltrion Inc, Catalent Inc.
Customization Scope Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing and Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of GMP Biologics Market

Global GMP Biologics Market- By Type

  • Monoclonal Antibodies
  • Polyclonal Antibody

GMP biologics

Global GMP Biologics Market – By Application

  • Hospitals
  • Clinics
  • Others

Global GMP Biologics Market – By Region

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa

 

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

The GMP Biologics Market Size is valued at USD 52.3 Bn in 2023 and is predicted to reach USD 153.9 Bn by the year 2031

The GMP Biologics Market is expected to grow at an 14.6% CAGR during the forecast period for 2024-2031.

Amgen Inc., F. Hoffmann-La Roche Ltd, AbbVie Inc., AstraZeneca plc, Merck KGaA, Creative Diagnostics, Fisher Bioservices (Thermo Fisher Scientific), P
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