Global Protein Design and Engineering Market Size is valued at USD 6.4 Billion in 2024 and is predicted to reach USD 25.1 Billion by the year 2034 at a 15.0 % CAGR during the forecast period for 2025-2034.
Key Industry Insights & Findings from the Report:
The Protein engineering and designing techniques are used to identify specific amino acid sequence changes and alter this sequence for desired functional properties. Mainly computational simulation methods and experimental/molecular methods are utilized for protein engineering.
Major factors such as increasing government initiatives & funding for the development of protein designing systems, fast advancements in technologies are primarily driving the market growth. High prevalence of protein-deficient diseases, and the surging demand for protein engineering tools by biopharmaceutical companies is also expected to support the market growth. The increasing collaborations between companies operating in this market to develop new testing technologies and accelerate the resource-intensive process of protein engineering are enhancing the growth opportunities of the protein design and engineering market. For instance, in January 2021, Zymvol Biomodeling (Spain) collaborated with Aminoverse, a biotech company specializing in enzyme discovery and design, to develop custom-made alcohol dehydrogenases, an enzyme most commonly used in the flavors and fragrances and the fine chemicals industry.
However, the expensive instruments and the increasing maintenance cost of the protein engineering equipment may hinder the market growth during the estimated timeframe.
The Protein design and engineering market is segmented into the protein engineering approach used, protein types, type of application, end-users, and region. The protein engineering approach used segment comprises rational designing, directed evolution, and semi-rational designing. The rational designing segment is estimated to dominate this market during the forecast period due to its rising use in antibody and enzyme designing. The market is classified into antibodies, peptides, enzymes, vaccines, and others based on the protein types. The antibodies are expected to be the fastest-growing segment of this market, owing to their increasing applications in the medical sector. The market is grouped into therapeutics and diagnostics by type of application. The market is segmented into pharma/biotech firms, CROs (contract research organizations) & research, and academic institutes by end-users. The pharma/biotech firms are projected to hold a significant market share in the coming years due to the rising demand for advanced drug and therapy treatments to cure chronic diseases. Region-wise, the market is studied across North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa.
The Asia-Pacific market is likely to witness rapid growth during the forecast period (2019-2030) due to the well-established healthcare infrastructure, growing awareness regarding protein engineering, and the rising government efforts to develop protein designing methods.
| Report Attribute | Specifications |
| Market Size Value In 2024 | USD 6.4 Billion |
| Revenue Forecast In 2034 | USD 25.1 Billion |
| Growth Rate CAGR | CAGR of 15.0 % from 2025 to 2034 |
| Quantitative Units | Representation of revenue in US$ Bn, and CAGR from 2025 to 2034 |
| Historic Year | 2021 to 2024 |
| Forecast Year | 2025-2034 |
| Report Coverage | The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
| Segments Covered | By Protein Engineering Approach Used, Protein Types, Type Of Application, End-users |
| Regional Scope | North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
| Country Scope | U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South East Asia; South Korea |
| Competitive Landscape | ATUM (US), Creative BioMart (US), Creative Biostructure (US), Creative Enzymes (US), Absolute Antibody (UK), EUCODIS Bioscience (Austria), Fusion Antibodies (UK), Innovagen (Sweden), ZYMVOL (Spain), Averring Biotech, EnzymeWorks (China), GeNext Genomics (India), Quantumzyme (India), and others. |
| Customization Scope | Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape. |
| Pricing And Available Payment Methods | Explore pricing alternatives that are customized to your specific requirements. |
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Protein Design and Engineering Market Snapshot
Chapter 4. Global Protein Design and Engineering Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis
Chapter 5. Market Segmentation 1: By Protein Types, Estimates & Trend Analysis
5.1. By Protein, & Market Share, 2024 & 2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Protein:
5.2.1. Antibodies
5.2.2. Peptides
5.2.3. Enzymes
5.2.4. Vaccines
5.2.5. Other Proteins
Chapter 6. Market Segmentation 2: By Type of Protein Engineering Approach Used Estimates & Trend Analysis
6.1. By Protein Engineering Approach Used & Market Share, 2024 & 2034
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Protein Engineering Approach Used:
6.2.1. Rational Designing
6.2.2. Directed Evolution
6.2.3. Semi-Rational Designing
Chapter 7. Market Segmentation 3: By Type of Application Estimates & Trend Analysis
7.1. By Applications & Market Share, 2024 & 2034
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Applications:
7.2.1. Therapeutics
7.2.2. Diagnostics
Chapter 8. Market Segmentation 4: By End-Users Estimates & Trend Analysis
8.1. By End-Users & Market Share, 2024 & 2034
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By End-Users
8.2.1. Pharma / Biotech Firms
8.2.2. CROs and Research
8.2.3. Academic Institutes
Chapter 9. Protein Design and Engineering Market Segmentation 5: Regional Estimates & Trend Analysis
9.1. North America
9.1.1. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts By Protein, 2021-2034
9.1.2. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts By Protein Engineering Approach Used, 2021-2034
9.1.3. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.1.4. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.1.5. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.2. Europe
9.2.1. Europe Protein Design and Engineering Market revenue (US$ Million) By Protein, 2021-2034
9.2.2. Europe Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, 2021-2034
9.2.3. Europe Protein Design and Engineering Market revenue (US$ Million) By Applications, 2021-2034
9.2.4. Europe Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.2.5. Europe Protein Design and Engineering Market revenue (US$ Million) by country, 2021-2034
9.3. Asia Pacific
9.3.1. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) By Protein, 2021-2034
9.3.2. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, 2021-2034
9.3.3. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) By Applications, 2021-2034
9.3.4. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.3.5. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) by country, 2021-2034
9.4. Latin America
9.4.1. Latin America Protein Design and Engineering Market revenue (US$ Million) By Protein, (US$ Million) 2021-2034
9.4.2. Latin America Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, (US$ Million) 2021-2034
9.4.3. Latin America Protein Design and Engineering Market revenue (US$ Million) By Applications, (US$ Million) 2021-2034
9.4.4. Latin America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.4.5. Latin America Protein Design and Engineering Market revenue (US$ Million) by country,2021-2034
9.5. Middle East & Africa
9.5.1. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) By Protein, (US$ Million) 2021-2034
9.5.2. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, (US$ Million) 2021-2034
9.5.3. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) By Applications, (US$ Million) 2021-2034
9.5.4. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.5.5. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) by country, 2021-2034
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. ATUM
10.2.2. Creative BioMart
10.2.3. Creative Biostructure
10.2.4. Creative Enzymes
10.2.5. Absolute Antibody
10.2.6. EUCODIS Bioscience
10.2.7. Fusion Antibodies
10.2.8. Innovagen
10.2.9. ZYMVOL
10.2.10. Averring Biotech
10.2.11. EnzymeWorks
10.2.12. GeNext Genomics
10.2.13. Quantumzyme
10.2.14. Other Prominent Players
Global Protein Design and Engineering Market, by Type of Protein Engineering Approach Used,
Global Protein Design and Engineering Market, by Protein Types,
Global Protein Design and Engineering Market, by Type of Application,
Global Protein Design and Engineering Market, by End-Users,
Global Protein Design and Engineering Market, by Region,
North America Protein Design and Engineering Market, by Country,
Europe Protein Design and Engineering Market, by Country,
Asia Pacific Protein Design and Engineering Market, by Country,
Latin America Protein Design and Engineering Market, by Country,
Middle East & Africa Protein Design and Engineering Market, by Country,