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Global Live Biotherapeutic Product (LBP) Market

Live Biotherapeutic Product (LBP) Market Size, Share & Trends Analysis Report By Product (VOWST (SER-109), REBYOTA, Visbiome, Other Pipeline Products), By Target Disease Indication, By Route Of Administration, By Region, And Segment Forecasts, 2023-2031.

Report ID : 1300 | Published : 2023-08-14 | Pages: 180 | Format: PDF/EXCEL

The Live Biotherapeutic Product (LBP) Market is expected to grow at a 21.2 % CAGR during the forecast period for 2023-2031.

Live Biotherapeutic Product (LBP) Market

A live microbe is utilized in a Live Biotherapeutic product to treat, prevent, or cure a disease. Microorganisms that may be beneficial to health have been discovered as the human microbiome, and its relationship to human health has come to be better understood. These microorganisms have a lot of potential for use as Live Biotherapeutic products in clinical settings. Several clinical trials are being conducted to assess their potential as a treatment. LBPs are believed to have biological effects by modulating the host-microbiota rather than directly acting on known targets or distant organs, tissues, or receptors. Importantly, LBPs will have a biological effect by influencing the local ecosystem, other microorganisms, and their interactions with the host.

Throughout the forecast period, market growth is anticipated to be driven by rising research and development efforts, as well as an expanding pipeline of microbiome-targeting therapies that are anticipated to treat a wide range of serious diseases. The development of new drugs and clinical trial activities for the treatment of diseases are being aided by ongoing innovation and technological advancements.

In 2019, 4D pharma collaborated with MSD to research and develop Live Biotherapeutics for vaccines. 4D's proprietary MicroRx® platform will be combined with MSD's expertise in developing and commercializing novel vaccines. During the forecast period, significant growth opportunities are anticipated as government funding and the R&D budget for drug development both increases. Over 640 patents focused on microbiome therapeutics were approved in 2020. The complexities occur due to a lack of expertise, specialized infrastructure, the need for astronomical capital expenditures, capacity limitations, and restrictions on ensuring compliance with good manufacturing practices (GMP).

Market Segmentation:

The Live Biotherapeutic Product Market is segmented into By Product Which consists of VOWST (SER-109), REBYOTA, Visbiome, Other Pipeline Products. Whereas, By Target Disease Indication the market is segmented into Recurrent C. Difficile Infection, Irritable Bowel Syndrome (IBS), Ulcerative Colitis (UC), Antibiotic-Associated Diarrhea (AAD), Pouchitis, Hepatic Encephalopathy (HE), Graft Versus Host Disease, Necrotizing Enterocolitis, Primary Hyperoxaluria, Other Indications. The last segment is Route Of Administration which includes Oral and Rectal Therapeutics.

Regionally, North America is anticipated to experience brisk growth during the forecast period (2022-2030) as a result of rising demand and the significant COVID-19 effect. Large sums of money are given to businesses to research Live Biotherapeutic ingredients and create new products.

Competitive Landscape:

Some Of The Key Players In The Live Biotherapeutic Product (LBP) Market:

  • Seres Therapeutics, Inc.
  • Microbiotica
  • Enterome
  • Destiny Pharma plc
  • Taisho Pharmaceutical Holdings
  • AOBiome Therapeutics, Inc.
  • Finch Therapeutics Group, Inc
  • Ferring Pharmaceuticals
  • Rebiotix Inc. (A Subsidiary of Ferring Pharmaceuticals)
  • MaaT Pharma
  • Vedanta Biosciences Inc.
  • OxThera AB
  • Pendulum Therapeutics
  • Caelus Health
  • Quorum Innovations
  • Sanofi S.A
  • DermBiont, Inc.
  • EnteroBiotix Ltd
  • YSOPIA Bioscience
  • Winclove Probiotics
  • TargEDys
  • Evelo Biosciences, Inc.
  • BiomX
  • Biomica Ltd.
  • Scioto Biosciences, Inc.
  • Lactobio A/S
  • Takeda Pharmaceutical Co. Ltd.
  • Second Genome Therapeutics
  • Johnson and Johnson Inc.
  • Kaleido Biosciences Inc.
  • OptiBiotix Health Plc
  • PureTech Health Plc
  • Immuron Limited
  • Naked Biome
  • Synthetic Biologics
  • ExeGi Pharma
  • Nexbiome
  • Mybiotics Pharma LTD. 

The Live Biotherapeutic Product (LBP) Market Report Scope:

Report Attribute

Specifications

Market Size Value In 2022

USD 432.24 Million

Revenue Forecast In 2031

USD 3048.51 Million

Growth Rate CAGR

CAGR of 23.46 % from 2023 to 2031

Quantitative Units

Representation of revenue in US$ Million and CAGR from 2023 to 2031

Historic Year

2019 to 2022

Forecast Year

2023-2031

Report Coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments Covered

By Product, By Target Disease Indication, By Route Of Administration

Regional Scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country Scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia

Competitive Landscape

Seres Therapeutics, Inc., Microbiotica, Enterome, Destiny Pharma plc, Taisho Pharmaceutical Holdings, AOBiome Therapeutics, Inc., Finch Therapeutics Group, Inc, Ferring Pharmaceuticals, Rebiotix Inc. (A Subsidiary of Ferring Pharmaceuticals), MaaT Pharma, Vedanta Biosciences Inc., OxThera AB, Pendulum Therapeutics, Caelus Health, Quorum Innovations, Sanofi S.A, DermBiont, Inc., EnteroBiotix Ltd, YSOPIA Bioscience, Winclove Probiotics, TargEDys, Evelo Biosciences, Inc., BiomX, Biomica Ltd., Scioto Biosciences, Inc., Lactobio A/S, Takeda Pharmaceutical Co. Ltd., Second Genome Therapeutics, Johnson and Johnson Inc., Kaleido Biosciences Inc., OptiBiotix Health Plc, PureTech Health Plc, Immuron Limited, Naked Biome, Synthetic Biologics, ExeGi Pharma, Nexbiome, Mybiotics Pharma LTD and others.

Customization Scope

Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.

Pricing And Available Payment Methods

Explore pricing alternatives that are customized to your particular study requirements.

Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global Live Biotherapeutic Product (LBP) Market Snapshot

Chapter 4. Global Live Biotherapeutic Product (LBP) Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: By Products, Estimates & Trend Analysis
5.1. By Products, & Market Share, 2019 & 2031
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By Products:
5.2.1. VOWST (SER-109)
5.2.2. REBYOTA
5.2.3. Visbiome
5.2.4. Other Pipeline Products

Chapter 6. Market Segmentation 2: By Target Disease Indication Estimates & Trend Analysis
6.1. By Target Disease Indication & Market Share, 2019 & 2031
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By Target Disease Indication:
6.2.1. Recurrent C. Difficile Infection
6.2.2. Irritable Bowel Syndrome (IBS)
6.2.3. Ulcerative Colitis (UC)
6.2.4. Antibiotic-Associated Diarrhea (AAD)
6.2.5. Pouchitis
6.2.6. Hepatic Encephalopathy (HE)
6.2.7. Graft Versus Host Disease
6.2.8. Necrotizing Enterocolitis
6.2.9. Primary Hyperoxaluria
6.2.10. Other Indications

Chapter 7. Market Segmentation 3: By Route of Administration Estimates & Trend Analysis
7.1. By Route of Administration & Market Share, 2019 & 2031
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2022 to 2031 for the following By Route of Administration:
7.2.1. Oral Therapeutics
7.2.2. Rectal Therapeutics

Chapter 8. Live Biotherapeutic Product (LBP) Market Segmentation 5: Regional Estimates & Trend Analysis
8.1. North America
8.1.1. North America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) estimates and forecasts By Products, 2019-2031
8.1.2. North America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) estimates and forecasts By Target Disease Indication, 2019-2031
8.1.3. North America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) estimates and forecasts By Route of Administration, 2019-2031
8.1.4. North America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) estimates and forecasts by country, 2019-2031

8.2. Europe
8.2.1. Europe Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Products, 2019-2031
8.2.2. Europe Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Target Disease Indication, 2019-2031
8.2.3. Europe Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Route of Administration, 2019-2031
8.2.4. Europe Live Biotherapeutic Product (LBP) Market revenue (US$ Million) by country, 2019-2031

8.3. Asia Pacific
8.3.1. Asia Pacific Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Products, 2019-2031
8.3.2. Asia Pacific Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Target Disease Indication, 2019-2031
8.3.3. Asia Pacific Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Route of Administration, 2019-2031
8.3.4. Asia Pacific Live Biotherapeutic Product (LBP) Market revenue (US$ Million) by country, 2019-2031

8.4. Latin America
8.4.1. Latin America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Products, (US$ Million) 2019-2031
8.4.2. Latin America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Target Disease Indication, (US$ Million) 2019-2031
8.4.3. Latin America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Route of Administration, (US$ Million) 2019-2031
8.4.4. Latin America Live Biotherapeutic Product (LBP) Market revenue (US$ Million) by country, 2019-2031

8.5. Middle East & Africa
8.5.1. Middle East & Africa Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Products, (US$ Million) 2019-2031
8.5.2. Middle East & Africa Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Target Disease Indication, (US$ Million) 2019-2031
8.5.3. Middle East & Africa Live Biotherapeutic Product (LBP) Market revenue (US$ Million) By Route of Administration, (US$ Million) 2019-2031
8.5.4. Middle East & Africa Live Biotherapeutic Product (LBP) Market revenue (US$ Million) by country, 2019-2031


Chapter 9. Competitive Landscape
9.1. Major Mergers and Acquisitions/Strategic Alliances
9.2. Company Profiles

9.2.1. Seres Therapeutics, Inc.
9.2.2. Microbiotica
9.2.3. Enterome
9.2.4. Destiny Pharma plc
9.2.5. Taisho Pharmaceutical Holdings
9.2.6. AOBiome Therapeutics, Inc.
9.2.7. Finch Therapeutics Group, Inc
9.2.8. Ferring Pharmaceuticals
9.2.9. Rebiotix Inc. (A Subsidiary of Ferring Pharmaceuticals)
9.2.10. MaaT Pharma
9.2.11. Vedanta Biosciences Inc.
9.2.12. OxThera AB
9.2.13. Pendulum Therapeutics
9.2.14. Caelus Health
9.2.15. Quorum Innovations
9.2.16. Sanofi S.A
9.2.17. DermBiont, Inc.
9.2.18. EnteroBiotix Ltd
9.2.19. YSOPIA Bioscience
9.2.20. Winclove Probiotics
9.2.21. TargEDys
9.2.22. Evelo Biosciences, Inc.
9.2.23. BiomX
9.2.24. Biomica Ltd.
9.2.25. Scioto Biosciences, Inc.
9.2.26. Lactobio A/S
9.2.27. Takeda Pharmaceutical Co. Ltd.
9.2.28. Second Genome Therapeutics
9.2.29. Johnson and Johnson Inc.
9.2.30. Kaleido Biosciences Inc.
9.2.31. OptiBiotix Health Plc
9.2.32. PureTech Health Plc
9.2.33. Immuron Limited
9.2.34. Naked Biome
9.2.35. Synthetic Biologics
9.2.36. ExeGi Pharma
9.2.37. Nexbiome
9.2.38. Mybiotics Pharma LTD.
9.2.39. Other Prominent Players

 

Segmentation Of Live Biotherapeutic Product (LBP) Market

Global Live Biotherapeutic Product (LBP) Market, by Product, 2023-2031 (Value US$ Mn)

  • VOWST (SER-109)
  • REBYOTA
  • Visbiome
  • Other Pipeline Products

Live Biotherapeutic Product (LBP) Market

Global Live Biotherapeutic Product (LBP) Market, by Target Disease Indication, 2023-2031 (Value US$ Mn)

  • Recurrent C. Difficile Infection
  • Irritable Bowel Syndrome (IBS)
  • Ulcerative Colitis (UC)
  • Antibiotic-Associated Diarrhea (AAD)
  • Pouchitis
  • Hepatic Encephalopathy (HE)
  • Graft Versus Host Disease
  • Necrotizing Enterocolitis
  • Primary Hyperoxaluria
  • Other Indications

Global Live Biotherapeutic Product (LBP) Market, by Route Of Administration, 2023-2031 (Value US$ Mn)

  • Oral Therapeutics
  • Rectal Therapeutics

Global Live Biotherapeutic Product (LBP) Market, by Region, 2023-2031 (Value US$ Mn)

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

North America Live Biotherapeutic Product (LBP) Market, by Country, 2023-2031 (Value US$ Mn)

  • U.S.
  • Canada

Europe Live Biotherapeutic Product (LBP) Market, by Country, 2023-2031 (Value US$ Mn)

  • Germany
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe

Asia Pacific Live Biotherapeutic Product (LBP) Market, by Country, 2023-2031 (Value US$ Mn)

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America Live Biotherapeutic Product (LBP) Market, by Country, 2023-2031 (Value US$ Mn)

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa Live Biotherapeutic Product (LBP) Market, by Country, 2023-2031 (Value US$ Mn)

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Landscape

  • Company Overview
  • Financial Performance
  • Key Development
  • Latest Strategic Developments

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

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The Live Biotherapeutic Product (LBP) Market is expected to grow at a 21.2 % CAGR during the forecast period for 2023-2031.

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