Live biotherapeutic/Microbiome Based Therapeutics Market Size is valued at USD 73.25 Bn in 2024 and is predicted to reach USD 142.81 Bn by the year 2034 at a 7.04% CAGR during the forecast period for 2025-2034.
A live microbe is utilized in a Live Biotherapeutic product to treat, prevent, or cure a disease. Microorganisms that may be beneficial to health have been discovered as the human microbiome, and its relationship to human health has come to be better understood. These microorganisms have a lot of potential for use as Live Biotherapeutic products in clinical settings. Several clinical trials are being conducted to assess their potential as a treatment. LBPs are believed to have biological effects by modulating the host-microbiota rather than directly acting on known targets or distant organs, tissues, or receptors. Importantly, LBPs will have a biological effect by influencing the local ecosystem, other microorganisms, and their interactions with the host.
Throughout the forecast period, market growth is anticipated to be driven by rising research and development efforts, as well as an expanding pipeline of microbiome-targeting therapies that are anticipated to treat a wide range of serious diseases. The development of new drugs and clinical trial activities for the treatment of diseases are being aided by ongoing innovation and technological advancements.
In 2019, 4D pharma collaborated with MSD to research and develop Live Biotherapeutics for vaccines. 4D's proprietary MicroRx® platform will be combined with MSD's expertise in developing and commercializing novel vaccines. During the forecast period, significant growth opportunities are anticipated as government funding and the R&D budget for drug development both increases. Over 640 patents focused on microbiome therapeutics were approved in 2020. The complexities occur due to a lack of expertise, specialized infrastructure, the need for astronomical capital expenditures, capacity limitations, and restrictions on ensuring compliance with good manufacturing practices (GMP).
The Live Biotherapeutic Product Market is segmented into By Product Which consists of VOWST (SER-109), REBYOTA, Visbiome, Other Pipeline Products. Whereas, By Target Disease Indication, the segmentation includes Recurrent C. Difficile Infection, Dietary Management of Microbial Imbalance, Other Indications. The segment Route Of Administration which includes Oral and Rectal Therapeutics. The Distribution Channel segment consists of Direct Sales, Pharmacies, Online Platforms. Whereas, By End User, the market is divided into Healthcare Facilities, Home Healthcare.
Regionally, North America is anticipated to experience brisk growth during the forecast period as a result of rising demand and the significant COVID-19 effect. Large sums of money are given to businesses to research Live Biotherapeutic ingredients and create new products.
| Report Attribute | Specifications |
| Market Size Value In 2024 | USD 73.25 Bn |
| Revenue Forecast In 2034 | USD 142.81 Bn |
| Growth Rate CAGR | CAGR of 7.04% from 2025 to 2034 |
| Quantitative Units | Representation of revenue in US$ Million and CAGR from 2025 to 2034 |
| Historic Year | 2021 to 2024 |
| Forecast Year | 2025-2034 |
| Report Coverage | The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
| Segments Covered | By Product, Target Disease Indication, Route Of Administration, Distribution channel, end user |
| Regional Scope | North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
| Country Scope | U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ; France; Italy; Spain; South Korea; South East Asia |
| Competitive Landscape | 4D Pharma, Adiso Therapeutics, Alveolus Bio Inc, AOBiome Therapeutics Inc, Assembly Biosciences, Azitra, Biomica, Destiny Pharma, Destiny Pharma plc, EnteroBiotix Limited, Finch Therapeutics, Infant Bacterial Therapeutics AB, MaaT Pharma, Microbiotica, OSEL Inc, OxThera, Scioto Biosciences Inc, Second Genome, Seres Therapeutics, Servatus Limited, Siolta Therapeutics, Vedanta Biosciences, YSOPIA Bioscience. |
| Customization Scope | Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape. |
| Pricing And Available Payment Methods | Explore pricing alternatives that are customized to your particular study requirements. |
Live biotherapeutic/Microbiome Based Therapeutics Market By Product
Live biotherapeutic/Microbiome Based Therapeutics Market By Route Of Administration
Live biotherapeutic/Microbiome Based Therapeutics Market By Target Disease Indication
Live biotherapeutic/Microbiome Based Therapeutics Market By Distribution Channel
Live biotherapeutic/Microbiome Based Therapeutics Market By End User
Live biotherapeutic/Microbiome Based Therapeutics Market By Region
North America Live biotherapeutic/Microbiome Based Therapeutics Market, by Country,
Europe Live biotherapeutic/Microbiome Based Therapeutics Market, by Country,
Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market, by Country,
Latin America Live biotherapeutic/Microbiome Based Therapeutics Market, by Country,
Middle East & Africa Live biotherapeutic/Microbiome Based Therapeutics Market, by Country,
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Live biotherapeutic/Microbiome Based Therapeutics Market Snapshot
Chapter 4. Global Live biotherapeutic/Microbiome Based Therapeutics Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Porter's Five Forces Analysis
4.7. Incremental Opportunity Analysis (US$ MN), 2024-2034
4.8. Competitive Landscape & Market Share Analysis, By Key Player (2023)
4.9. Use/impact of AI on Live biotherapeutic/Microbiome Based Therapeutics Market Industry Trends
4.10. Global Live biotherapeutic/Microbiome Based Therapeutics Market Penetration & Growth Prospect Mapping (US$ Mn), 2021-2034
Chapter 5. Live biotherapeutic/Microbiome Based Therapeutics Market Segmentation 1: By Product, Estimates & Trend Analysis
5.1. Market Share by Product, 2024 & 2034
5.2. Market Size Revenue (US$ Million) & Forecasts and Trend Analyses, 2021 to 2034 for the following Product:
5.2.1. VOWST (SER-109)
5.2.2. REBYOTA
5.2.3. Visbiome
5.2.4. Other Pipeline Products
Chapter 6. Live biotherapeutic/Microbiome Based Therapeutics Market Segmentation 2: By Route of Administration, Estimates & Trend Analysis
6.1. Market Share by Route of Administration, 2024 & 2034
6.2. Market Size Revenue (US$ Million) & Forecasts and Trend Analyses, 2021 to 2034 for the following Route of Administration:
6.2.1. Oral Therapeutics
6.2.2. Rectal Therapeutics
Chapter 7. Live biotherapeutic/Microbiome Based Therapeutics Market Segmentation 3: Target Disease Indication, Estimates & Trend Analysis
7.1. Market Share by Target Disease Indication, 2024 & 2034
7.2. Market Size Revenue (US$ Million) & Forecasts and Trend Analyses, 2021 to 2034 for the following Target Disease Indication:
7.2.1. Recurrent C. Difficile Infection
7.2.2. Dietary management of microbial imbalance
7.2.3. Other Indications
Chapter 8. Live biotherapeutic/Microbiome Based Therapeutics Market Segmentation 4: By Distribution Channel, Estimates & Trend Analysis
8.1. Market Share by Distribution Channel, 2024 & 2034
8.2. Market Size Revenue (US$ Million) & Forecasts and Trend Analyses, 2021 to 2034 for the following Distribution Channel:
8.2.1. Direct Sales
8.2.2. Pharmacies
8.2.3. Online Platforms
Chapter 9. Live biotherapeutic/Microbiome Based Therapeutics Market Segmentation 5: By End User, Estimates & Trend Analysis
9.1. Market Share by End User, 2024 & 2034
9.2. Market Size Revenue (US$ Million) & Forecasts and Trend Analyses, 2021 to 2034 for the following End User:
9.2.1. Healthcare Facilities
9.2.2. Home Healthcare
Chapter 10. Live biotherapeutic/Microbiome Based Therapeutics Market Segmentation 6: Regional Estimates & Trend Analysis
10.1. Global Live biotherapeutic/Microbiome Based Therapeutics Market, Regional Snapshot 2024 & 2034
10.2. North America
10.2.1. North America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Country, 2021-2034
10.2.1.1. US
10.2.1.2. Canada
10.2.2. North America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Product, 2021-2034
10.2.3. North America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Route Of Administration, 2021-2034
10.2.4. North America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Target Disease Indication, 2021-2034
10.2.5. North America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Distribution Channel, 2021-2034
10.2.6. North America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by End User, 2021-2034
10.3. Europe
10.3.1. Europe Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Country, 2021-2034
10.3.1.1. Germany
10.3.1.2. U.K.
10.3.1.3. France
10.3.1.4. Italy
10.3.1.5. Spain
10.3.1.6. Rest of Europe
10.3.2. Europe Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Product, 2021-2034
10.3.3. Europe Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Route Of Administration, 2021-2034
10.3.4. Europe Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Target Disease Indication, 2021-2034
10.3.5. Europe Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Distribution Channel, 2021-2034
10.3.6. Europe Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by End User, 2021-2034
10.4. Asia Pacific
10.4.1. Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Country, 2021-2034
10.4.1.1. India
10.4.1.2. China
10.4.1.3. Japan
10.4.1.4. Australia
10.4.1.5. South Korea
10.4.1.6. Hong Kong
10.4.1.7. Southeast Asia
10.4.1.8. Rest of Asia Pacific
10.4.2. Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Product, 2021-2034
10.4.3. Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Route Of Administration, 2021-2034
10.4.4. Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Target Disease Indication, 2021-2034
10.4.5. Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Distribution Channel, 2021-2034
10.4.6. Asia Pacific Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by End User, 2021-2034
10.5. Latin America
10.5.1. Latin America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Country, 2021-2034
10.5.1.1. Brazil
10.5.1.2. Mexico
10.5.1.3. Rest of Latin America
10.5.2. Latin America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Product, 2021-2034
10.5.3. Latin America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Route Of Administration, 2021-2034
10.5.4. Latin America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Target Disease Indication, 2021-2034
10.5.5. Latin America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Distribution Channel, 2021-2034
10.5.6. Latin America Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by End User, 2021-2034
10.6. Middle East & Africa
10.6.1. Middle East & Africa Wind Turbine Rotor Blade Market Revenue (US$ Million) Estimates and Forecasts by country, 2021-2034
10.6.1.1. GCC Countries
10.6.1.2. Israel
10.6.1.3. South Africa
10.6.1.4. Rest of Middle East and Africa
10.6.2. Middle East & Africa Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Product, 2021-2034
10.6.3. Middle East & Africa Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Route Of Administration, 2021-2034
10.6.4. Middle East & Africa Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Target Disease Indication, 2021-2034
10.6.5. Middle East & Africa Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Distribution Channel, 2021-2034
10.6.6. Middle East & Africa Live biotherapeutic/Microbiome Based Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by End User, 2021-2034
Chapter 11. Competitive Landscape
11.1. Major Mergers and Acquisitions/Strategic Alliances
11.2. Company Profiles
11.2.1. Seres Therapeutics, Inc.
11.2.1.1. Business Overview
11.2.1.2. Key Solution/Service Overview
11.2.1.3. Financial Performance
11.2.1.4. Geographical Presence
11.2.1.5. Recent Developments with Business Strategy
11.2.2. 4D Pharma
11.2.3. Adiso Therapeutics
11.2.4. Alveolus Bio Inc
11.2.5. AOBiome Therapeutics, Inc.
11.2.6. Assembly Biosciences
11.2.7. Azitra
11.2.8. Biomica
11.2.9. Destiny Pharma
11.2.10. Destiny Pharma plc
11.2.11. EnteroBiotix Limited
11.2.12. Finch Therapeutics
11.2.13. Infant Bacterial Therapeutics AB
11.2.14. MaaT Pharma
11.2.15. Microbiotica
11.2.16. OSEL INC.
11.2.17. OxThera
11.2.18. Scioto Biosciences, Inc.
11.2.19. Second Genome
11.2.20. Seres Therapeutics
11.2.21. Servatus Limited
11.2.22. Siolta Therapeutics
11.2.23. Vedanta Biosciences
11.2.24. YSOPIA Bioscience
11.2.25. Other prominent player