Gastroesophageal Reflux Disease Therapeutics Market Size, Share & Trends Analysis Report By Drug Type (Antacids, H2 Receptor Blockers, Proton Pump Inhibitors (PPIs), and Pro-Kinetic Agents), By Region, And Segment Forecasts, 2025-2034

Report Id: 1705 Pages: 180 Published: 04 July 2025 Format: PDF / PPT / Excel / Power BI
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Global Gastroesophageal Reflux Disease Therapeutics Market Size is valued at USD 4.9 Bn in 2021 and is predicted to reach USD 5.9  Bn by the year 2034 at a 1.9% CAGR during the forecast period for 2025-2034.

Key Industry Insights & Findings from the Report:  

  • The demand for gastroesophageal reflux disease therapeutics is expected to rise due to the increasing number of initiatives by the government and non-governmental organizations to combat malnutrition.
  • Investing in creating new raw materials and producing finished food items are considered driving forces in the market's growth.
  • North America dominated the market and accounted for a revenue share of global revenue in 2024.
  • The government's rising preference for local components is expected to slow the expansion of the GERD industry. 

Gastroesophageal Reflux Disease Therapeutics Market

Due to factors such as the low success rates associated with GERD management devices, an increase in the frequency of GERD and other gastrointestinal problems, and a rising tendency of self-medication supported by a robust product pipeline, the market for GERD treatments is expanding. Lockdowns have brought about significant lifestyle changes. The COVID-19 lockdown, remote work, sedentary lives, boredom, and anxiety directly impact people's eating patterns. There was a significant (P 0.001) rise in the number of meals, snacks, binges, and unhealthy food intake throughout the COVID-19-induced home confinement period. 

Determining which people have GERD is one of the most challenging parts of calculating the condition's prevalence. Many patients with GERD-related symptoms do not seek treatment from a primary care physician (PCP). Those who do often send patients to a gastroenterologist only when symptoms stop responding to treatment after seeking PCP therapy (refractory). GERD also has a significant economic impact since the expense of long-term disease management is high because it is a chronic rather than an acute illness. 

Recent Developments:

  • In Nov 2023, Phathom Pharmaceuticals' Voquezna (vonoprazan) tablets have been authorized by the FDA for the treatment of erosive esophagitis, sometimes referred to as erosive GERD (gastroesophageal reflux disease), in adults. It is also prescribed as a maintenance therapy for erosive gastroesophageal reflux disease (GERD) and for the alleviation of heartburn linked to erosive GERD.
  • In Oct 2022, EndoStim has been granted the FDA's Breakthrough Device designation for its EndoStim System, which is used to treat patients suffering from gastroesophageal reflux disease (GERD) who do not experience relief from medication therapy.Competitive Landscape:

Some of the Gastroesophageal Reflux Disease Therapeutics market players are:

  • AstraZeneca;
  • Aurobindo Pharma Limited
  • Cadila Pharmaceuticals Limited
  • Camber Pharmaceuticals Inc.
  • CHEPLAPHARM Arzneimittel GmbH
  • Daewoong Pharmaceutical Co., Ltd
  • Eisai Co. Ltd.
  • EndoStim, Inc.
  • GlaxoSmithKline PLC
  • Ironwood Pharmaceuticals, Inc.;
  • Jeil Pharmaceutical Co., Ltd.
  • Johnson & Johnson Services, Inc.
  • Novartis AG
  • Phathom Pharmaceuticals Inc.
  • Reckitt Benckiser Group PLC
  • Sebela Pharmaceuticals
  • SFJ Pharmaceuticals Group
  • SRS Life Sciences Pte. Ltd.
  • Sun Pharmaceutical Industries Limited
  • Takeda Pharmaceutical Company Limited.
  • Teva Pharmaceuticals Industries Limited 

Market Segmentation:

The Gastroesophageal Reflux Disease Therapeutics market is segmented on the basis of drug type. Based on drug type, the market is categorized as Antacids, H2 Receptor Blockers, Proton Pump Inhibitors (PPIs), and Pro-kinetic agents.

Based On Drug Type, The Antacids Segment Is Accounted As A Significant Contributor In The Gastroesophageal Reflux Disease Therapeutics Market

The bioalcohols category is expected to hold a major share in the global Gastroesophageal Reflux Disease Therapeutics market in 2021. The success and speedy relief that antacids offer are credited with the segment's dominance. Customers seeking treatment from acid reflux and heartburn spend billions of dollars on antacids, one of the most popular classes of over-the-counter pharmaceuticals available worldwide. They treat GERD, heartburn, acid indigestion, hyperacidity, and upset stomach symptoms brought on by these conditions. The segment's expansion can also be linked to the public's growing understanding of self-medication. Consumers prefer over-the-counter medications to professional medical services. Antacids have also been discovered to be helpful and have no adverse side effects in pregnancy and other diseases, further fueling the segment's rise.

The North America Gastroesophageal Reflux Disease Therapeutics Market Holds A Significant Revenue Share In The Region

Due to the rising prevalence of GERD in the local population, North America dominated the global gastroesophageal reflux disease treatment market in 2023. This trend can be due to the increasing use of GERD therapies. For instance, research that appeared in the journal GUT found that 18–28% of people in North America had GERD. Furthermore, there are more and more campaigns to raise public awareness of the problem, which is driving up demand for GERD treatments. For instance, EndoGastric Solutions, Inc. began a national campaign to support GERD awareness week in November 2022. The campaign's goal was to give GERD sufferers simple-to-follow reflux-friendly recipes.

Gastroesophageal Reflux Disease Therapeutics Market Report Scope:

Report Attribute Specifications
Market size value in 2024 USD 4.9 Bn
Revenue forecast in 2034 USD  5.9 Bn
Growth rate CAGR CAGR of 1.9% from 2025 to 2034
Quantitative units Representation of revenue in US$ Million, and CAGR from 2025 to 2034
Historic Year 2021 to 2024
Forecast Year 2025-2034
Report coverage The forecast of revenue, the position of the company, the competitive market statistics, growth prospects, and trends
Segments covered Drug Type
Regional scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; Southeast Asia; South Korea; Southeast Asia
Competitive Landscape AstraZeneca; Eisai Co. Ltd.; GSK plc.; Takeda Pharmaceutical Company Limited.; Ironwood Pharmaceuticals, Inc.; Johnson & Johnson Services; Inc.; SFJ Pharmaceuticals; Sebela Pharmaceuticals; Phathom Pharmaceuticals Inc.; Camber Pharmaceuticals Inc.
Customization scope Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing and available payment methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of Gastroesophageal Reflux Disease Therapeutics Market:

Gastroesophageal Reflux Disease Therapeutics Market By Drug Type-

  • Antacids
  • H2 Receptor Blockers
  • Proton Pump Inhibitors (PPIs)
  • Pro-kinetic agents 

Gastroesophageal Reflux Disease Therapeutics Market

Gastroesophageal Reflux Disease Therapeutics Market By Region-

North America-

  • The US
  • Canada

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • South East Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

Need specific information/chapter from the report of the custom data table, graph or complete report? Tell us more.

Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global Gastroesophageal Reflux Disease Therapeutics Market Snapshot

Chapter 4. Global Gastroesophageal Reflux Disease Therapeutics Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: by Drug Type Estimates & Trend Analysis
5.1. by Drug Type & Market Share, 2024 & 2034
5.2. Market Size (Value (US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following by Drug Type:

5.2.1. Antacids
5.2.2. H2 Receptor Blockers
5.2.3. Proton Pump Inhibitors (PPIs)
5.2.4. Pro-kinetic agents

Chapter 6. Gastroesophageal Reflux Disease Therapeutics Market Segmentation 2: Regional Estimates & Trend Analysis

6.1. North America

6.1.1. North America Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Drug Type, 2021-2034
6.1.2. North America Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by country, 2021-2034

6.2. Europe

6.2.1. Europe Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Drug Type, 2021-2034
6.2.2. Europe Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by country, 2021-2034

6.3. Asia Pacific

6.3.1. Asia Pacific Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Drug Type, 2021-2034
6.3.2. Asia Pacific Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by country, 2021-2034

6.4. Latin America

6.4.1. Latin America Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Drug Type, 2021-2034
6.4.2. Latin America Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by country, 2021-2034

6.5. Middle East & Africa

6.5.1. Middle East & Africa Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by Drug Type, 2021-2034
6.5.2. Middle East & Africa Gastroesophageal Reflux Disease Therapeutics Market Revenue (US$ Million) Estimates and Forecasts by country, 2021-2034

Chapter 7. Competitive Landscape

7.1. Major Mergers and Acquisitions/Strategic Alliances

7.2. Company Profiles


7.2.1. AstraZeneca;
7.2.2. Aurobindo Pharma Limited
7.2.3. Cadila Pharmaceuticals Limited
7.2.4. Camber Pharmaceuticals Inc.
7.2.5. CHEPLAPHARM Arzneimittel GmbH
7.2.6. Daewoong Pharmaceutical Co., Ltd
7.2.7. Eisai Co. Ltd.
7.2.8. EndoStim, Inc.
7.2.9. GlaxoSmithKline PLC
7.2.10. Ironwood Pharmaceuticals, Inc.;
7.2.11. Jeil Pharmaceutical Co., Ltd.
7.2.12. Johnson & Johnson Services, Inc.
7.2.13. Novartis AG
7.2.14. Phathom Pharmaceuticals Inc.
7.2.15. Reckitt Benckiser Group PLC
7.2.16. Sebela Pharmaceuticals
7.2.17. SFJ Pharmaceuticals Group
7.2.18. SRS Life Sciences Pte. Ltd.
7.2.19. Sun Pharmaceutical Industries Limited
7.2.20. Takeda Pharmaceutical Company Limited.
7.2.21. Teva Pharmaceuticals Industries Limited
7.2.22. Other Prominent Players

Segmentation of Gastroesophageal Reflux Disease Therapeutics Market:

Gastroesophageal Reflux Disease Therapeutics Market By Drug Type-

  • Antacids
  • H2 Receptor Blockers
  • Proton Pump Inhibitors (PPIs)
  • Pro-kinetic agents 

Gastroesophageal Reflux Disease Therapeutics Market By Region-

North America-

  • The US
  • Canada

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • South East Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa
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Frequently Asked Questions

Gastroesophageal Reflux Disease Therapeutics Market Size is valued at USD 4.9 Bn in 2024 and is predicted to reach USD 5.9 Bn by the year 2034

Gastroesophageal Reflux Disease Therapeutics Market expected to grow at a 1.9% CAGR during the forecast period for 2025-2034

AstraZeneca; Eisai Co. Ltd.; GSK plc.; Takeda Pharmaceutical Company Limited.; Ironwood Pharmaceuticals, Inc.; Johnson & Johnson Services; Inc.; SFJ P

Drug Type are the key segments of the Gastroesophageal Reflux Disease Therapeutics Market.

North America region is leading the Gastroesophageal Reflux Disease Therapeutics Market.
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