Coagulation Factor Deficiency Market Size, Share & Trends Analysis Report By Deficiency Type (Hemophilia A, Hemophilia B, Von Willebrand Disease, Factor XI Deficiency, Factor XIII Deficiency, and Others), By Product Type, By End Users, By Region, And By Segment Forecasts, 2024-2031

Report Id: 2163 Pages: 179 Last Updated: 13 March 2024 Format: PDF / PPT / Excel / Power BI
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Coagulation Factor Deficiency Market Size is valued at USD 5.50 Bn in 2023 and is predicted to reach USD 9.60 Bn by the year 2031 at a 7.36% CAGR during the forecast period for 2024-2031. 

Coagulation Factor Deficiency

Coagulation factor deficiency refers to a medical disorder characterized by an inadequate or malfunctioning of coagulation factors, which are proteins responsible for blood clotting. This can result in hemorrhagic diseases, manifesting as signs such as facile ecchymosis, protracted bleeding following traumas, and excessive menstrual bleeding. Treatment entails the substitution of the missing factor or the use of medicines to induce clotting. There has been an increase in government funding, along with efforts from governmental and private organizations, to promote rising awareness and understanding of this disease. Furthermore, advancements in medical technology, genetic counselling, and the growing adoption of early screening methods are anticipated to accelerate market growth.

Additionally, to further stimulate the demand for factor VII treatment products, it is essential to conduct awareness campaigns and educational programs targeting both healthcare professionals and patients. These initiatives can lead to earlier detection and treatment of bleeding disorders, ultimately enhancing the quality of care for affected individuals. Notably, there is substantial variation in the prevalence, diagnosis, and treatment approaches for coagulation factor deficiencies across different regions and countries. This diversity can present challenges in developing standardized global treatment strategies.

Competitive Landscape

Some Major Key Players In The Coagulation Factor Deficiency Market:

  • Pfizer Inc
  • Grifols
  • Biogen
  • Octapharma
  • Baxter
  • Bayer
  • CSL Behring
  • Novo Nordisk
  • Greencross
  • Kedrion
  • BPL
  • Hualan Bio
  • RAAS
  • Ferring B.V.,
  • Hoffmann-La Roche AG,
  • Others

Market Segmentation:

The coagulation factor deficiency market is segmented on the basis of deficiency type, product and end users. Based on deficiency type, the coagulation factor deficiency market is segmented as Haemophilia A, Haemophilia B, von Willebrand disease, factor xi deficiency, factor xiii deficiency and others. By product, the Coagulation Factor Deficiency market is segmented into recombinant coagulation factor concentrates, plasma-derived coagulation factor concentrates, biologics, desmopressin and others. By product, the coagulation factor deficiency market is segmented into hospitals, clinics, home care and others.

Based On End Users, The Hospital Segment Is Accounted As A Major Contributor To The Coagulation Factor Deficiency Market. 

The hospital category is expected to record a major share of the global coagulation factor deficiency market in 2024. Increasing hospital demand in the coagulation factor deficiency market suggests that hospitals are experiencing a growing need for resources and services to address coagulation factor deficiencies, reflecting a rising trend in healthcare demands associated with this medical condition. Hospitals play a crucial role in diagnosing and treating patients with such conditions, so their demand for relevant resources is vital. This indicates the market associated with products and services related to coagulation factor deficiencies. This market includes items like factor VII treatment products, diagnostic tools, medications, and other healthcare services directed at individuals with coagulation factor deficiencies.

The Biologics Segment Witnessed Growth At A Rapid Rate.

The biologics segment is projected to grow at a rapid rate in the global coagulation factor deficiency market. Biologics are typically derived from living organisms and are used for various medical purposes, including the treatment of specific health conditions. This represents the market related to products and services addressing coagulation factor deficiencies. In this context, it includes biological treatments, medications, therapies, and other healthcare offerings designed for individuals with coagulation factor deficiencies. The term "increasing" signifies that the demand for biologic-based treatments for coagulation factor deficiencies is on the rise. This may be due to various factors, such as the effectiveness of biologics in treating these conditions, advancements in biotechnology, or changes in healthcare practices that prioritize biologic therapies. 

In The Region, The North American Coagulation Factor Deficiency Market Holds A Significant Revenue Share.

The North American Coagulation Factor Deficiency market is expected to register a tremendous market share in terms of revenue in the near future. The market in this region may exhibit specific trends, such as increasing healthcare expenditures, a growing ageing population, changes in healthcare policies, and advancements in medical technology, all of which can impact the demand and supply of coagulation factor deficiency-related products and services.

In addition, Asia Pacific's regional market is projected to grow at a rapid rate. Each of these countries may have distinct healthcare systems, regulations, and market conditions, contributing to the diversity within the Coagulation Factor Deficiency Market in APAC. Factors Influencing the Market. Several factors can influence this market, including the prevalence of coagulation factor deficiencies, healthcare infrastructure, regulatory frameworks, awareness among healthcare professionals and the public, and the availability of treatment options, including factor VII treatment products and other therapies. 

Recent Developments:

  • In Oct 2022, Novo Nordisk has disclosed that Health Canada has approved a novel indication of REBINYN® (Coagulation Factor IX (Recombinant), pegylated): the management of routine prophylaxis in patients with haemophilia B who are below the age of 18. In all ages afflicted with haemophilia B (congenital factor IX deficiency or Christmas disease), one REBINYN® is recommended for routine prophylaxis to control and prevent bleeding, control and prevent bleeding episodes, and control and prevent bleeding in a perioperative setting.
  • In April 2019, Grifols contributed more than 100 Bn international units (IUs) of blood clotting factor medications worldwide as a part of its long-term dedication to the World Federation of Hemophilia (WFH) in underdeveloped areas. Grifols established the Grifols Hemophilia Awareness Global Awards to bolster the worldwide effort to combat the illness.

Coagulation Factor Deficiency Market Report Scope

Report Attribute Specifications
Market Size Value In 2023 USD 5.50 Bn
Revenue Forecast In 2031 USD 9.60 Bn
Growth Rate CAGR CAGR of 7.36% from 2024 to 2031
Quantitative Units Representation of revenue in US$ Bn and CAGR from 2024 to 2031
Historic Year 2019 to 2023
Forecast Year 2024-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Deficiency Type, Product Type, End-User
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; Southeast Asia
Competitive Landscape Pfizer Inc, Grifols, Biogen, Octapharma, Baxter, Bayer, CSL Behring, Novo Nordisk, Greencross, Kedrion, BPL, Hualan Bio, RAAS, Ferring B.V., F. Hoffmann-La Roche AG, and Others
Customization Scope Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing And Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of Coagulation Factor Deficiency Market-

Coagulation Factor Deficiency Market By Deficiency Type

  • Hemophilia A
  • Hemophilia B
  • Von Willebrand Disease
  • Factor XI Deficiency
  • Factor XIII Deficiency
  • Others 

Coagulation Factor Deficiency

Coagulation Factor Deficiency Market By Product Type

  • Plasma-derived coagulation Factor Concentrates
  • Recombinant Coagulation Factor Concentrates
  • Biologics
  • Desmopressin
  • Others

Coagulation Factor Deficiency Market By End Users

  • Hospitals
  • Clinics
  • Homecare
  • Others

Coagulation Factor Deficiency Market By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

Coagulation Factor Deficiency Market Size is valued at USD 5.50 Bn in 2023 and is predicted to reach USD 9.60 Bn by the year 2031

Coagulation Factor Deficiency Market is expected to grow at a 7.36% CAGR during the forecast period for 2024-2031.

Novo Nordisk, Greencross, Kedrion, BPL, Hualan Bio, RAAS, Ferring B.V., F. Hoffmann-La Roche AG, and Others
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