Global mRNA Synthesis and Manufacturing Services Market Size is valued at USD 958.52 Mn in 2024 and is predicted to reach USD 2,294.90 Mn by the year 2034 at a 7.7% CAGR during the forecast period for 2025-2034.
In 2024 market has grown exponentially due to the success of the COVID-19 vaccines, and it has created a massive demand for a consistent supply of vaccines. However, in 2022 market is expected to decrease at the growth rate of -42.0%. The mRNA Synthesis and Manufacturing Services market other than COVID 19 application are under development which offers immense growth and penetration opportunities in the forecast period. By region, Asia Pacific dominates the mRNA synthesis and manufacturing services market with share of 33.4% of total global market.
Due to its versatile and flexible nature, mRNA is an excellent platform for developing prophylactic or therapeutic vaccines against various chronic and infectious diseases. Compared to conventional medicines, mRNA vaccines have higher effectiveness, improved immunogenicity, and required less manufacturing cost. The constant innovations and improvements in mRNA synthesis and manufacturing services are expected to propel the market growth of mRNA synthesis and manufacturing services over the forecast period. During the current Covid-2019 pandemic, many companies have chosen mRNA vaccine technology to combat coronavirus.
For instance, in November 2020, Pfizer Inc. and BioNTech SE announced their mRNA-based vaccine candidate, BNT162b2, against SARS-CoV-2 had demonstrated evidence of efficacy against COVID-19 in participants without prior evidence of SARS-CoV-2 infection.
The increasing need for gene therapies, growing chronic and infectious diseases, and the rising number of clinical trials for cancer therapies and infectious diseases are likely to evolve the mRNA synthesis and manufacturing services market at a considerable rate in the next few years. Furthermore, advanced medical technologies, increasing customizable facilities, improving quality and efficacy services, and novel innovations by pharmaceutical companies enhance the market growth.
However, the lack of flexible, sustainable, and cost-effective manufacturing processes hinders the growth of mRNA synthesis and manufacturing services.Segmentation of mRNA synthesis and manufacturing services market includes Products, Applications, Scale of Operation, and Region. The market can be segmented into API and Drug Products based on Products. By Applications, the market is categorized into Infectious Disease Vaccines, Other Vaccines, Therapeutics and Others. Based on the Scale of Operation, the market is segmented into Research / Preclinical, Clinical, and Commercial. Regionally, the mRNA synthesis and manufacturing services market can be divided into North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa. North America, followed by Europe and the Asia Pacific, holds the maximum share of this market due to increased research and development expenditure, increased prevalence of infectious diseases, and the fast adoption of advanced technologies.
CDMO Organizations
Custom Synthesis/cGMP Service Providers:
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Report Attribute |
Specifications |
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Market Size Value In 2024 |
USD 958.52 Mn |
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Revenue Forecast In 2034 |
USD 2,294.90 Mn |
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Growth Rate CAGR |
CAGR of 7.7% from 2025 to 2034 |
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Quantitative Units |
Representation of revenue in US$ Million and CAGR from 2025 to 2034 |
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Historic Year |
2021 to 2024 |
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Forecast Year |
2025-2034 |
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Report Coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
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Segments Covered |
By Type of Industry, Application, Scale of operations, Product, Therapeutic Area |
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Regional Scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
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Country Scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ; France; Italy; Spain; South Korea; South East Asia; |
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Competitive Landscape |
eTheRNA (Etherna Immunotherapies), Celonic AG, Corden Pharma GmbH, Lonza Group AG, Rentschler Biopharma, Laboratorios Farmacéuticos Rovi, S.A., Samsung Biologics, Thermo Fisher Scientific, Sartorius AG (BIA Separations), AGC Biologics, FUJIFILM Diosynth Biotechnologies, Hanmi Pharmaceutical, Arranta Bio, ST Pharm, BioCina Pty Ltd., Curia Global, Inc. and Others |
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Customization Scope |
Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape. |
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Pricing And Available Payment Methods |
Explore pricing alternatives that are customized to your particular study requirements. |
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global mRNA Synthesis and Manufacturing Services Market Snapshot
Chapter 4. Global mRNA Synthesis and Manufacturing Services Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis
4.9. Clinical Trial/Pipeline Analysis
Chapter 5. Market Segmentation 1: By Product Estimates & Trend Analysis
5.1. By Type of Industry & Market Share, 2024 & 2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Type of Industry:
5.2.1. API
5.2.2. Drug Products
Chapter 5. Market Segmentation 2: By Type of Industry Estimates & Trend Analysis
5.1. By Type of Industry & Market Share, 2024 & 2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Type of Industry:
5.2.1. Therapeutics and Vaccine Developers
5.2.2. CDMO Organizations
5.2.3. Custom Synthesis/cGMP Service Providers
Chapter 6. Market Segmentation 3: By Therapeutic Area Estimates & Trend Analysis
6.1. By Therapeutic Area & Market Share, 2024 & 2034
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Applications:
6.2.1. Infectious Disease
6.2.2. Oncological Disorders
6.2.3. Others
Chapter 7. Market Segmentation 4: By Scale of Operation Estimates & Trend Analysis
7.1. By Scale of Operation & Market Share, 2024 & 2034
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Scale of Operation:
7.2.1. Research / Preclinical
7.2.2. Clinical
7.2.3. Commercial
Chapter 8. Market Segmentation 4: By Application Estimates & Trend Analysis
8.1. By Application & Market Share, 2024 & 2034
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Application:
8.2.1. mRNA-based Vaccines
8.2.2. mRNA-based Therapeutics
Chapter 9. mRNA Synthesis and Manufacturing Services Market Segmentation 5: Regional Estimates & Trend Analysis
9.1. North America
9.1.1. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Products, 2021-2034
9.1.2. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.1.3. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2021-2034
9.1.4. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Therapeutic Area, 2021-2034
9.1.5. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Type of Industry, 2021-2034
9.1.6. North America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.2. Europe
9.2.1. EuropemRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Products, 2021-2034
9.2.2. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.2.3. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2021-2034
9.2.4. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Therapeutic Area, 2021-2034
9.2.5. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Type of Industry, 2021-2034
9.2.6. Europe mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.3. Asia Pacific
9.3.1. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Products, 2021-2034
9.3.2. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.3.3. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2021-2034
9.3.4. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Therapeutic Area, 2021-2034
9.3.5. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Type of Industry, 2021-2034
9.3.6. Asia Pacific mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.4. Latin America
9.4.1. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Products, 2021-2034
9.4.2. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.4.3. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2021-2034
9.4.4. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Therapeutic Area, 2021-2034
9.4.5. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Type of Industry, 2021-2034
9.4.6. Latin America mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.5. Middle East & Africa
9.5.1. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Products, 2021-2034
9.5.2. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.5.3. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2021-2034
9.5.4. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Therapeutic Area, 2021-2034
9.5.5. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts By Type of Industry, 2021-2034
9.5.6. Middle East & Africa mRNA Synthesis and Manufacturing Services Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. Eurogentec
10.2.2. Aldevron
10.2.3. eTheRNA (Etherna Immunotherapies)
10.2.4. bioSYNTHESIS
10.2.5. TriLink BioTechnologies
10.2.6. Biomay
102.7. Jena Biosciences
10.2.8. APExBIO
10.2.9. CELLSCRIPT
10.2.10. Thermo Fisher Scientific
10.2.11. New England Biolabs
10.2.12. Celonic AG
10.2.13. Corden Pharma GmbH
10.2.14. Lonza Group AG
10.2.15. Rentschler Biopharma
10.2.16. Laboratorios Farmacéuticos Rovi, S.A.
10.2.17. Samsung Biologics
10.2.18. CureVac
10.2.19. Moderna
10.2.20. BioNTech (Pfizer)
10.2.21. Translate Bio
10.2.22. Ethris (AstraZeneca)
10.2.23. Kernal Biologics
10.2.24. Silence Therapeutics
10.2.25. Tiba Biotechnology
10.2.26. In-Cell-Art
10.2.27. Anima Biotech
10.2.28. H3 Biomedicine Inc.
10.2.29. Arcturus Therapeutics
10.2.30. eFFECTOR Therapeutics, Inc.
10.2.31. Ionis Pharmaceuticals, Inc.
10.2.32. Stemirna Therapeutics Co., Ltd.
10.2.33. Skyhawk Therapeutics, Inc.
10.2.34. RNAimmune (Sirnaomics)
10.2.35. Ziphius Therapeutics NV
10.2.36. miRagen Therapeutics, Inc.
10.2.37. Strand Therapeutics Inc.
10.2.38. Other Prominent Players
mRNA Synthesis and Manufacturing Services Market By Products-
mRNA Synthesis and Manufacturing Services Market By Type of Industry-
mRNA Synthesis and Manufacturing Services Market By Therapeutic Area-
mRNA Synthesis and Manufacturing Services Market By Scale of Operation-
mRNA Synthesis and Manufacturing Services Market By Application-
mRNA Synthesis and Manufacturing Services Market By Region-
North America-
Europe-
Asia-Pacific-
Latin America-
Middle East & Africa-
InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.
Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.
Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.
Secondary research
The secondary research sources that are typically mentioned to include, but are not limited to:
The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista
Primary Research:
Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies
The contributors who typically take part in such a course include, but are not limited to:
Data Modeling and Analysis:
In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.
The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.
To know more about the research methodology used for this study, kindly contact us/click here.
