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Lipid-Nanoparticle Based Genomic Medicines Market

Lipid-Nanoparticle Based Genomic Medicines Market Size, Share & Trends Analysis Report By MoA (Gene Addition/Replacement, Gene Expression Control, Gene Editing, DNA/RNA Vaccines), By Application (Cancer Treatment, Infectious Diseases, Genetic Disorders, Cardiovascular Diseases, Others), By End-User, By Region, And By Segment Forecasts, 2024-2031

Report ID : 2380 | Published : 2024-07-09 | Pages: 180 | Format: PDF/EXCEL

Lipid-Nanoparticle Based Genomic Medicines Market Size is valued at USD 2.6 Bn in 2024 and is predicted to reach USD 22.0 Bn by the year 2031 at a 31.0 % CAGR during the forecast period for 2024-2031.

Key Industry Insights & Findings from the Report:

  • The shift towards customized medicine is driving the lipid-nanoparticle-based genomic medicines market.
  • The rise in mRNA-based therapeutics, enabled by lipid nanoparticles, is a significant growth factor.
  • North America dominated the market and accounted for a global revenue share in 2023.
  • Navigating the complex regulatory landscape and achieving approvals for LNP-based genomic medicines is another key challenge for the market.

LNP

LNP-based genetic medicines are leading the way in personalized and precision medicine, providing hopeful new therapy possibilities for a diverse array of disorders. Their development and therapeutic application are subjects of ongoing research, having the potential to completely transform the approach to treating genetic and infectious disorders.

Ongoing breakthroughs in nanotechnology, including lipid-based nanoparticles, are driving the development of precise and efficient delivery techniques for genetic therapies, enhancing the effectiveness of these medications. Another driving force behind the adoption of genomic pharmaceuticals, specifically mRNA-based treatments, is their potential to treat a variety of ailments, including genetic disorders, cancer, and infectious diseases. This necessitates the development of delivery mechanisms for lipid nanoparticles. The use of cancer apps serves as an additional incentive. 

In this changing landscape, research, strategic alliances, and regulatory advances emphasize lipid-nanoparticle-based genetic medicines as transformative treatments in the age of personalised healthcare. Recent technology platforms include lipid nanoparticles (LNPs). With LNP delivery technologies, over two billion people have received COVID-19 mRNA immunizations or boosters.

Competitive Landscape

Some Major Key Players In The Lipid-Nanoparticle Based Genomic Medicines Market:

  • Moderna Inc.
  • Pfizer Inc.
  • BioNTech SE
  • Arbutus Biopharma Corporation
  • Arrowhead Pharmaceuticals Inc.
  • CureVac N.V.
  • Lipocalyx
  • Acuitas Therapeutics
  • Precision NanoSystems Inc.
  • IONTAS Limited
  • Genevant Sciences
  • Roche Holding AG
  • Alnylam Pharmaceuticals Inc.
  • SiO2 Materials Science
  • Ethris GmbH
  • BIOVECTRA
  • Avanti Polar Lipids, Inc. (Croda International Plc.),
  • Recipharm AB
  • eTheRNA
  • ST Pharm Co Ltd,
  • Other Prominent Players

Market Segmentation:

The Lipid-Nanoparticle Genomic Medicines Market can be segmented based on MoA, Application, and End-User. By MoA, the market is segmented into Gene Addition/Replacement, Gene Expression Control, Gene Editing, DNA/RNA Vaccines. The Application segment of the market includes Cancer Treatment, Infectious Diseases, Genetic Disorders, Cardiovascular Diseases, and Others. By Therapeutic Payload, the market is segmented into mRNA-based Therapeutics, siRNA-based Therapeutics, miRNA-based Therapeutics, and Other Genomic Medicines. The End-User segment comprises Hospitals, Biopharmaceutical Companies, Research Institutes, and Others.

North America Has A Significant Revenue Share In The Lipid-Nanoparticle Genomic Medicines Market Region.

In the region, North America leads the Lipid-Nanoparticle Genomic Medicines Market in terms of revenue share. The broad use of mRNA-based vaccinations and treatments is the main trend in North America. Sufficient funding for biopharmaceutical research fosters innovation, with a particular emphasis on extending the use of lipid-nanoparticle genetic therapies to disorders such as neurodegenerative ones.

The region's leadership in the development of genetic medicine is partly attributed to regulatory backing and partnerships between academics and business. Europe and the Asia-Pacific region place a strong emphasis on sustainable lipid nanoparticle technology. Research on environmentally friendly lipid formulations and resolving environmental issues are trends. Additionally, the region is home to cooperative efforts in precision oncology, with an emphasis on lipid-based drug delivery system improvements and personalised genetic therapy.

Recent Developments:

  • In December 2023, ReciBioPharm, the advanced therapies division of Recipharm, and biotech company Acuitas Therapeutics are elevating their partnership to offer technology transfers and CGMP manufacturing for customers licensing Acuitas’ lipid nanoparticle (LNP) formulations for mRNA-based therapeutics and vaccines.

Lipid-Nanoparticle Based Genomic Medicines Market Report Scope

Report Attribute

Specifications

Market Size Value In 2024

USD 2.6 Bn

Revenue Forecast In 2031

USD 22.0 Bn

Growth Rate CAGR

CAGR of 31.0% from 2024 to 2031

Quantitative Units

Representation of revenue in US$ Million and CAGR from 2024 to 2031

Historic Year

2019 to 2023

Forecast Year

2024-2031

Report Coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments Covered

By MoA, Application and End-User

Regional Scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country Scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South East Asia; South Korea

Competitive Landscape

Moderna Inc., Pfizer Inc., BioNTech SE, Arbutus Biopharma Corporation, Arrowhead Pharmaceuticals Inc., CureVac N.V., Lipocalyx, Acuitas Therapeutics, Precision NanoSystems Inc., IONTAS Limited, Genevant Sciences, Roche Holding AG, Alnylam Pharmaceuticals Inc., SiO2 Materials Science, Ethris GmbH, BIOVECTRA, Avanti Polar Lipids, Inc. (Croda International Plc.), Recipharm AB, eTheRNA, ST Pharm Co Ltd, and Other market players

Customization Scope

Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape.

Pricing And Available Payment Methods

Explore pricing alternatives that are customized to your particular study requirements.

Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global Lipid-Nanoparticle Based Genomic Medicines Market Snapshot

Chapter 4. Global Lipid-Nanoparticle Based Genomic Medicines Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: by MoA Estimates & Trend Analysis
5.1. by MoA & Market Share, 2023 & 2031
5.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by MoA:

5.2.1. Gene Addition/Replacement
5.2.2. Gene Expression Control
5.2.3. Gene Editing
5.2.4. DNA/RNA Vaccines

Chapter 6. Market Segmentation 2: by Application Estimates & Trend Analysis
6.1. by Application & Market Share, 2023 & 2031
6.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by Application;

6.2.1. Cancer Treatment
6.2.2. Infectious Diseases
6.2.3. Genetic Disorders
6.2.4. Cardiovascular Diseases
6.2.5. Others

Chapter 7. Market Segmentation 3: by End-User Estimates & Trend Analysis
7.1. by End-User & Market Share, 2023 & 2031
7.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by End-User:

7.2.1. Hospitals
7.2.2. Research Institutes
7.2.3. Others

Chapter 8. Lipid-Nanoparticle Based Genomic Medicines Market Segmentation 4: Regional Estimates & Trend Analysis

8.1. North America
8.1.1. North America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by MoA, 2024-2031
8.1.2. North America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
8.1.3. North America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2024-2031
8.1.4. North America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.2. Europe
8.2.1. Europe Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by MoA, 2024-2031
8.2.2. Europe Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
8.2.3. Europe Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2024-2031
8.2.4. Europe Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.3. Asia Pacific
8.3.1. Asia Pacific Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by MoA, 2024-2031
8.3.2. Asia Pacific Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
8.3.3. Asia Pacific Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2024-2031
8.3.4. Asia Pacific Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.4. Latin America
8.4.1. Latin America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by MoA, 2024-2031
8.4.2. Latin America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
8.4.3. Latin America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2024-2031
8.4.4. Latin America Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.5. Middle East & Africa
8.5.1. Middle East & Africa Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by MoA, 2024-2031
8.5.2. Middle East & Africa Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
8.5.3. Middle East & Africa Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by End-User, 2024-2031
8.5.4. Middle East & Africa Lipid-Nanoparticle Based Genomic Medicines Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

Chapter 9. Competitive Landscape
9.1. Major Mergers and Acquisitions/Strategic Alliances
9.2. Company Profiles

9.2.1. Moderna Inc.
9.2.2. Pfizer Inc.
9.2.3. BioNTech SE
9.2.4. Arbutus Biopharma Corporation
9.2.5. Arrowhead Pharmaceuticals Inc.
9.2.6. CureVac N.V.
9.2.7. Lipocalyx
9.2.8. Acuitas Therapeutics
9.2.9. Precision NanoSystems Inc.
9.2.10. IONTAS Limited
9.2.11. Genevant Sciences
9.2.12. Roche Holding AG
9.2.13. Alnylam Pharmaceuticals Inc.
9.2.14. SiO2 Materials Science
9.2.15. Ethris GmbH
9.2.16. Others

Segmentation of Lipid-Nanoparticle-Based Genomic Medicines Market-

Lipid-Nanoparticle-Based Genomic Medicines Market By MoA-

  • Gene Addition/Replacement
  • Gene Expression Control
  • Gene Editing
  • DNA/RNA Vaccines

 LNP

Lipid-Nanoparticle-Based Genomic Medicines Market By Application-

  • Cancer Treatment
  • Infectious Diseases
  • Genetic Disorders
  • Cardiovascular Diseases
  • Others

Lipid-Nanoparticle-Based Genomic Medicines Market By End-User-

  • Hospitals
  • Research Institutes
  • Others

Lipid-Nanoparticle-Based Genomic Medicines Market By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • South East Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

How big is the Lipid-Nanoparticle Based Genomic Medicines Market Size?

Lipid-Nanoparticle Based Genomic Medicines Market is expected to grow at a 31.0% CAGR during the forecast period for 2024-2031.

SiO2 Materials Science, Ethris GmbH, BIOVECTRA, Avanti Polar Lipids, Inc. (Croda International Plc.), Recipharm AB, eTheRNA, ST Pharm Co Ltd, and Othe

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