Global Viral Vector Purification Market Size is valued at USD 267.5 Mn in 2024 and is predicted to reach USD 1485.2 Mn by the year 2034 at a 18.8% CAGR during the forecast period for 2025-2034.
Over 1,000 cell and gene therapy-related clinical trials are currently underway worldwide. Gene delivery vectors are critical in the development of cell and gene therapies since genetic manipulation is a prerequisite. So far, viral vectors (based on adeno-associated viruses (AAV), adenoviruses, lentiviruses, retroviruses, and other viruses) have been demonstrated to be the most versatile gene delivery tools available, with high transfection efficiencies in both preclinical and clinical settings. Besides that, given the therapeutic efficacy and low side effect profiles of cell and gene therapies, demand for such interventions is expected to rise rapidly, necessitating a proportional increase in demand for appropriate vector systems.
Various techniques are currently used to purify viral vectors. Size-based viral purification strategies, such as density-gradient ultracentrifugation, ultrafiltration, precipitation, and size-exclusion chromatography (SEC), have become industry standards over the years.Following the Covid-19 pandemic, many governments realized the importance of establishing research institutes in the fields of gene therapy and vaccine development. This trend of increasing investment in biotech and pharmaceutical companies is expected to boost the global market for viral vector products. Furthermore, the rising demand for synthetic genes and the untapped market potential are expected to show lucrative growth opportunities for market players in the future.
The global viral vector purification market is segmented on the basis of product type, purification technique type, type of viral vector scope, and scale of operation. By product type, the market is segmented as a kit, prepacked column, resin, cassette, filter plate, capsule, and reagent. The other purification technique type segment includes chromatography, centrifugation, and filtration. The market is segmented by type of viral vector scope into AAV, adenovirus, lentivirus, retrovirus, and others. The scale of operation segment includes lab-scale, clinical, and commercial.
In 2020, AAV dominated the market with a significant market share. Due to their use in the majority of cell-based gene therapies, the adeno-associated viral vector manufacturing segment is anticipated to grow at the highest CAGR during the forecast period. Some of the significant facts that enable it to occupy a significant share of this vector in the overall market are its ability to integrate with large transgenes and simple production at high levels. Several companies and state organizations have successfully developed an AAV-based vaccine to prevent Covid-19 infection.
In 2020, the clinical segment had the highest market share. The rising engagement of scientific communities in gene and cell therapy research is predicted to raise demand for viral vectors due to the high need for vectors for conducting research.
Furthermore, research organisations, pharmaceutical, and biopharmaceutical enterprises are developing as significant end-users of the market for viral vectors and plasmid DNA synthesis, adding to the launch of advanced medications and the number of gene therapy-based R&D activities. One of these companies, Abeona Therapeutics, is testing AAV9-based gene therapies for CLN1 and CLN3 disorders. As a result, it will fuel market growth.
North America dominated the global viral vector purification market, accounting for nearly 50% of all revenue in 2020. This region has the highest demand for viral vector CDMO due to the concentration of research and development in the domain of advanced genetic therapies. The United States is the leading country in this region and the world in terms of revenue generation through ADVAC viral vector technology services. In addition, Investments made by federal agencies to expand the region's cell therapy research base are expected to boost the growth of the North American market. Besides, the Asia Pacific region is likely the fastest-growing region due to a growing patient population, increased R&D activities in this field, and other factors. Furthermore, patients from Western countries travel to Asian countries for stem cell therapy because the legal framework in this region is less restrictive.
Furthermore, the region's large population and untapped potential have resulted in a business shift for global firms in this region. Moreover, this region provides reasonably priced manufacturing and operating units for conducting research. These factors are expected to play a significant role in the expansion of the stem cell field in this region, boosting market growth even further.
| Report Attribute | Specifications |
| Market size value in 2024 | USD 267.5 Mn |
| Revenue forecast in 2034 | USD 1485.2 Mn |
| Growth rate CAGR | CAGR of 18.8% from 2025 to 2034 |
| Quantitative units | Representation of revenue in US$ Mn and CAGR from 2025 to 2034 |
| Historic Year | 2021 to 2024 |
| Forecast Year | 2025-2034 |
| Report coverage | The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
| Segments covered | By Products Type, By Purification Technique Type, By Type of Viral Vector Scope, By Scale of Operation |
| Regional scope | North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
| Country scope | U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia |
| Competitive Landscape | Agilent Technologies, BIA Separations, Bio-Rad Laboratories, BioVision, Cytiva (formerly GE Lifesciences), Merck, Sartorius, Takara Bio, and Thermo Fisher Scientific. |
| Customization scope | Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape. |
| Pricing and available payment methods | Explore pricing alternatives that are customized to your particular study requirements. |
Global Viral Vector Purification Market By Product Type -
Global Viral Vector Purification Market By Purification Technique Type -
Global Viral Vector Purification Market By Type of Viral Vector Scope -
Global Viral Vector Purification Market By Scale of Operation -
Global Viral Vector Purification Market By Region -
North America -
Europe -
Asia-Pacific -
Latin America -
Middle East & Africa -
Rest of Middle East and Africa
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Viral Vector Purification / Virus Purification Products Market Snapshot
Chapter 4. Global Viral Vector Purification / Virus Purification Products Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Industry Analysis – Porter’s Five Forces Analysis
4.6. Competitive Landscape & Market Share Analysis
4.7. Major Investment, Partnerships and Collaborations in Gene Therapy Research
4.8. Covid-19 Impact on Healthcare Industry
Chapter 5. Market Segmentation 1: Product Type Estimates & Trend Analysis
5.1. Product Type & Market Share, 2024 & 2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Product Type:
5.2.1. Kit
5.2.2. Prepacked Column
5.2.3. Resin
5.2.4. Cassette
5.2.5. Filter Plate
5.2.6. Capsule
5.2.7. Reagent
Chapter 6. Market Segmentation 2: Type of Purification Technique Estimates & Trend Analysis
6.1. Type of Purification Technique & Market Share, 2024 & 2034
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Type of Purification Technique:
6.2.1. Chromatography
6.2.2. Centrifugation
6.2.3. Filtration
Chapter 7. Market Segmentation 3: Type of Viral Vector Estimates & Trend Analysis
7.1. Type of Viral Vector Type & Market Share, 2024 & 2034
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Type of Viral Vector Type:
7.2.1. AAV
7.2.2. Adenovirus
7.2.3. Lentivirus
7.2.4. Retrovirus
7.2.5. others
Chapter 8. Market Segmentation 4: Scale of Operation Estimates & Trend Analysis
8.1. Scale of Operation & Market Share, 2024 & 2034
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following Scale of Operation:
8.2.1. Lab-scale
8.2.2. Clinical
8.2.3. Commercial
Chapter 9. Viral Vector Purification / Virus Purification Products Market Segmentation 3: Regional Estimates & Trend Analysis
9.1. North America
9.1.1. North America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) estimates and forecasts by Product Type, 2021-2034
9.1.2. North America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) estimates and forecasts by Type of Purification Technique, 2021-2034
9.1.3. North America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) estimates and forecasts by Type of Viral Vector, 2021-2034
9.1.4. North America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) estimates and forecasts by Scale of Operation, 2021-2034
9.1.5. North America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.2. Europe
9.2.1. Europe Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Product Type, 2021-2034
9.2.2. Europe Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Purification Technique, 2021-2034
9.2.3. Europe Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Viral Vector, 2021-2034
9.2.4. Europe Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Scale of Operation, 2021-2034
9.2.5. Europe Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by country, 2021-2034
9.3. Asia Pacific
9.3.1. Asia Pacific Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Product Type, 2021-2034
9.3.2. Asia Pacific Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Purification Technique, 2021-2034
9.3.3. Asia Pacific Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Viral Vector, 2021-2034
9.3.4. Asia Pacific Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Scale of Operation, 2021-2034
9.3.5. Asia Pacific Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by country, 2021-2034
9.4. Latin America
9.4.1. Latin America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Product Type, (US$ Million) 2021-2034
9.4.2. Latin America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Purification Technique, (US$ Million) 2021-2034
9.4.3. Latin America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Viral Vector, (US$ Million) 2021-2034
9.4.4. Latin America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Scale of Operation, 2021-2034
9.4.5. Latin America Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by country, (US$ Million) 2021-2034
9.5. Middle East & Africa
9.5.1. Middle East & Africa Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Product Type, (US$ Million) 2021-2034
9.5.2. Middle East & Africa Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Purification Technique, (US$ Million) 2021-2034
9.5.3. Middle East & Africa Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Type of Viral Vector, (US$ Million) 2021-2034
9.5.4. Middle East & Africa Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by Scale of Operation, 2021-2034
9.5.5. Middle East & Africa Viral Vector Purification / Virus Purification Products Market revenue (US$ Million) by country, (US$ Million) 2021-2034
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. Agilent Technologies
10.2.2. BIA Separations
10.2.3. Bio-Rad Laboratories
10.2.4. BioVision
10.2.5. Cytiva (formerly GE Lifesciences)
10.2.6. Merck
10.2.7. Sartorius
10.2.8. Takara Bio
10.2.9. Thermo Fisher Scientific
10.2.10. Other Prominent Player