DNA/RNA Sample Extraction and Isolation Market Size, Share & Trends Analysis Report By Product (Consumables (Kits (DNA Kits, RNA Kits), Reagents), Instruments), By Technology (Consumable-Based Technology (Silica-Based, Magnetic Particle Technology, Other Technologies), Instrument-Based Technology (Automated Spin Column-Based, Magnetic Bead-Based, Automated Liquid Handling), By Application, By End-User, By Region, And By Segment Forecasts, 2024-2031

Report Id: 2199 Pages: 180 Last Updated: 07 March 2024 Format: PDF / PPT / Excel / Power BI
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DNA/RNA Sample Extraction and Isolation Market Size is valued at USD 2.47 Bn in 2023 and is predicted to reach USD 4.14 Bn by the year 2031 at a 6.80% CAGR during the forecast period for 2024-2031. 

DNA/RNA Sample Extraction and Isolation

The extraction and isolation of DNA/RNA samples are critical operations in molecular biology and genetics research. They involve the extraction of nucleic acids (DNA and RNA) from cells, tissues, or biological fluids for use in PCR, sequencing, genotyping, gene expression studies, and molecular diagnostics. The DNA/RNA sample extraction and isolation market is dynamic, with numerous variables driving its growth, technological advancements, and adoption. The expanding landscape of genome research, diagnostics, and personalized treatment shapes these market dynamics. The growing use of genomic medicine and personalized medicines involves the collection of high-quality DNA/RNA samples. To support their investigations and therapies, researchers and doctors demand effective extraction procedures.

However, the COVID-19 pandemic had a short-term impact on the DNA/RNA extraction kit market due to constraints on various commercial and research operations. Furthermore, the diagnostics tests for medical disorders and other diseases at hospitals and other diagnostics facilities were impacted due to a reduction in patient turnout for tests as a result of COVID-19. 

Competitive Landscape

Some Major Key Players In The DNA/RNA Sample Extraction and Isolation Market:

  • Abnova Corporation
  • Agilent Technologies, Inc.
  • Bio-Rad Laboratories, Inc.
  • Hoffmann-La Roche Ltd
  • Illumina, Inc.
  • MACHEREY-NAGEL GmbH & Co. KG
  • Merck KGaA
  • Norgen Biotek Corp.
  • Omega Bio-tek, Inc.
  • Promega Corporation
  • QIAGEN N.V.
  • Tecan Group
  • Thermo Fisher Scientific, Inc.
  • Zymo Research
  • Others

Market Segmentation:

The DNA/RNA Sample Extraction and Isolation Market is categorised on the basis of product, technology, application, and end-user. The product segment includes Consumables (Kits and Reagents) and Instruments. Kits subsegment includes DNA kits like Cell-free DNA, Genomic DNA, Microbe DNA, Plasmid DNA, Viral DNA. Whereas RNA kits include Cell-free RNA, Genomic RNA, Microbe RNA and Viral RNA.

The technology segment includes Consumable-Based Technology (Silica-Based, Magnetic Particle Technology, and Other Technologies) and Instrument-Based Technology (Automated Spin Column-Based, Magnetic Bead-Based, and Automated Liquid Handling). By application, the market is segmented into PCR, NGS, Cloning, Microarray, Blotting Techniques, and Other Applications. The end-user segment includes Clinical Diagnostic and Forensic Laboratories, Research Academics and Institutions, Pharmaceutical and Biotechnology companies, Contract Research Organizations, and Others.

Based On Product, The Consumables Segment Is A Major Contributor In The DNA/RNA Sample Extraction And Isolation Market. 

The Consumables category is expected to hold a major share of the global DNA/RNA Sample Extraction and Isolation Market in 2024. The consumables market for DNA/RNA sample extraction and isolation encompasses a diverse range of goods and kits required for the effective and consistent extraction and purification of nucleic acids. Consumables are the most common product type since they are used in practically all applications related to the worldwide DNA/RNA sample extraction and isolation market. Due to the increasing utilization of media, kits, and reagents, it is anticipated that this segment will continue to grow significantly in the forecasting period.

The PCR Segment Witnessed Growth At A Rapid Rate.

The PCR segment is projected to grow at a rapid rate in the global DNA/RNA Sample Extraction and Isolation Market. The market for DNA/RNA sample extraction and isolation for PCR applications is a critical part of the molecular diagnostics industry. The dynamics of this market are impacted by a number of factors, including the increased demand for dependable nucleic acid extraction methods for polymerase chain reaction (PCR) analysis. PCR is commonly used in many laboratories worldwide because it further amplifies DNA, allowing the examination of even extremely minute amounts of nucleic acid. PCR has been used in various domains, including illness detection, DNA profiling, precision medicine, and gene expression, as molecular biology techniques have advanced.

In The Region, The Asia Pacific DNA/RNA Sample Extraction And Isolation Market Holds A Significant Revenue Share.

The Asia Pacific DNA/RNA Sample Extraction and Isolation Market is expected to record the maximum market revenue share in the near future owing to rising demand for molecular diagnostics, genomics research, and an increase in infectious diseases. Due to massive R&D expenditure by the government and corporate entities, increasing demand for kits, and rising occurence of chronic diseases such as cancer, the United States is predicted to dominate the region's DNA/RNA extraction kit market. 

Recent Developments:

  • In July 2023, QIAGEN announced the release of the QIAseq Normalizer Kits, which provide researchers with a quick, easy, and cost-effective way to pool various DNA libraries for the best-quality results from next-generation sequencing (NGS) runs. The QIAseq Normalizer Kit reduces the time required to normalize DNA concentrations across NGS libraries from several hours to 30 minutes.
  • In March 2021, Tecan and Zymo Research collaborated on forces to create a ready-to-use processing system that makes it easier to get viral DNA and RNA from nasopharyngeal swabs, oropharyngeal swabs, saliva, sputum, plasma, and serum. The Zymo Research Quick-DNA/RNA™ Viral MagBead Kit on the DreamPrep NAP workstation made the process easier by pre-loading scripts that were tuned for viral RNA extraction and were being tested for COVID-19 assays by high-complexity testing labs

DNA/RNA Sample Extraction and Isolation Market Report Scope

Report Attribute Specifications
Market Size Value In 2023 USD 2.47 Bn
Revenue Forecast In 2031 USD 4.14 Bn
Growth Rate CAGR CAGR of 6.80% from 2024 to 2031
Quantitative Units Representation of revenue in US$ Million and CAGR from 2024 to 2031
Historic Year 2019 to 2023
Forecast Year 2024-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Product, Technology, Application, End-Use
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia
Competitive Landscape Abnova Corporation, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., F. Hoffmann-La Roche Ltd, Illumina, Inc., MACHEREY-NAGEL GmbH & Co. KG, Merck KGaA, Norgen Biotek Corp., Omega Bio-tek, Inc., Promega Corporation, QIAGEN N.V., Tecan Group, Thermo Fisher Scientific, Inc., and Zymo Research.
Customization Scope Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing And Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of DNA/RNA Sample Extraction and Isolation Market-

By Product-

  • Consumables
    • Kits
      • DNA Kits
        • Cell-Free DNA (cfDNA)
        • Genomic DNA
        • Microbe DNA
        • Plasmid DNA
        • Viral DNA
      • RNA Kits
        • Cell-Free RNA
        • Genomic RNA
        • Microbe RNA
        • Viral RNA
      • Reagents
    • Instruments

DNA/RNA Sample Extraction and Isolation

By Technology-

  • Consumable-Based Technology
    • Silica-Based
    • Magnetic Particle Technology
    • Other Technologies
  • Instrument-Based Technology
    • Automated Spin Column-Based
    • Magnetic Bead-Based
    • Automated Liquid Handling

By Application-

  • PCR
  • NGS
  • Cloning
  • Microarray
  • Blotting Techniques
  • Other Applications

By End-User-

  • Clinical Diagnostic and Forensic Laboratories
  • Research Academics and Institutions
  • Pharmaceutical and Biotechnology Companies
  • Contract Research Organizations
  • Others

By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

DNA/RNA Sample Extraction and Isolation Market Size is valued at USD 2.47 Bn in 2023 and is predicted to reach USD 4.14 Bn by the year 2031

DNA/RNA Sample Extraction and Isolation Market expected to grow at a 6.80% CAGR during the forecast period for 2024-2031.

Norgen Biotek Corp., Omega Bio-tek, Inc., Promega Corporation, QIAGEN N.V., Tecan Group, Thermo Fisher Scientific, Inc., and Zymo Research.
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