Pre-Fillable Syringe Closures and Accessories Market Size, Share & Trends Analysis Report By Product (Glass Syringes, Polymer Syringes), By End-User, By Region, And Segment Forecasts, 2024-2031

Report Id: 1222 Pages: 180 Last Updated: 17 August 2024 Format: PDF / PPT / Excel / Power BI
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The Pre-Fillable Syringe Closures and Accessories Market Size is valued at USD 2,188.38 Million in 2023 and is predicted to reach USD 4848.54 Million by the year 2031 at a 10.56% CAGR during the forecast period for 2024-2031. 

pre fillable syringe

The Pre-fillable syringe is specially designed to eliminate the withdrawal step and deliver the drug product directly to the patient, resulting in a more accurate drug dose with less exposure to needles. This syringe helps control the cost by minimizing overfill and reducing microbial contamination and medication dosing errors. The components of a pre-fillable syringe play an essential role in reducing contamination and handling problems. Stoppers, plungers, needle shields, rods, etc., are components of the syringe. Prefilled syringes are used for packaging injectable drugs and diluents. The drugs packaged in prefilled syringes are vaccines, blood stimulants, therapeutic proteins, erythroproteins, interferons, and rheumatoid arthritis. API of a combination product in continuous contact with the biologic drug, the plunger stopper plays a crucial role in determining the combination product's exposure to leachable and extractable. The European market for prefilled syringes is comparatively more mature than the US market.

The market's major driving factors are increasing demand for prefilled syringes, new requirements, and more sophisticated forms of drug delivery. Companies are collaborating on advanced developments in primary packaging and drug product interactions for more hygiene and accuracy, which is also responsible for the market's growth. Industrial investments are boosting the development and research regarding the finest syringes. In Dec 2020, BD announced the Investment of $1.2 Billion to upgrade the Pre-Fillable Syringe Manufacturing Capacity Over the Next Four Years. This investment includes a new manufacturing facility in Europe. In Feb 2022, West Pharmaceutical investing an additional $70M will add 70+ jobs in Kinston. The company's investment will enhance the production capacity, add warehouse and distribution space, and support the company's mission.

The limitations of the traditional medication administration technique include that it has unhygienic interactions, as well as interactions between prefilled syringes and the drug, which can cause stability concerns. The challenges for the prefilled syringe closures and accessories market are the safety system's low-cost alternative, and the requirement for more sophisticated forms of delivery as their requirements become more complex. Hence, the manufacturers need more significant investment to maintain competitiveness in the marketplace.

Market Segmetation

Global pre-fillable syringe closures and accessories market is segmented based on product and by end-user. Product segmentation is mainly devided into two subsegments: glass syringes, which consists of Plunger Stoppers, Plunger Rods, Backstops, Needle shields, Closure systems for luer lock syringes, Closure systems for luer cones syringes, Safety System/Component. Whereas polymer syringes include Plunger Stoppers, Plunger Rods, Backstops. End-user segmentation comprises Pharmaceutical & Biotechnology Companies, Contract Research & Manufacturing Organizations,    Other Institutes. Global Pre-Fillable Syringe Closures and Accessories Market contains North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa.

Regionally Europe is likely to witness the market growth, followed by North America due to rapid investments and partnership programmes for minimizing production errors and innovative developments for low cost and more user-friendly designs.

Competitive Landscape

Some Of The Key Players In The Pre-Fillable Syringe Closures and Accessories Market:

  • BD (Becton, Dickinson and Company),
  • Dätwyler Holding Inc.,
  • Gerresheimer AG,
  • West Pharmaceutical Services, Inc.,
  • AptarGroup, Inc.,
  • Nipro PharmaPackaging International,
  • Stevanato Group,
  • Helvoet Rubber & Plastic Technologies BV,
  • Nemera ,
  • chott AG,
  • L. Gore & Associates, Inc.,
  • Owen Mumford Ltd,
  • SANNER GMBH,
  • Other Prominent Player

The Pre-Fillable Syringe Closures and Accessories Market Report Scope

Report Attribute Specifications
Market Size Value In 2023 USD 2,188.38 Million
Revenue Forecast In 2031 USD 4,848.54 Million
Growth Rate CAGR CAGR of 10.57% from 2024 to 2031
Quantitative Units Representation of revenue in US$ Million and CAGR from 2024 to 2031
Historic Year 2019 to 2023
Forecast Year 2024-2031
Report Coverage The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends
Segments Covered By Product, By End-User
Regional Scope North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Country Scope U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia
Competitive Landscape BD (Becton, Dickinson and Company), Dätwyler Holding Inc., Gerresheimer AG, West Pharmaceutical Services, Inc., AptarGroup, Inc., Nipro PharmaPackaging International, Stevanato Group, Helvoet Rubber & Plastic Technologies BV, Nemera , chott AG, W. L. Gore & Associates, Inc., Owen Mumford Ltd, SANNER GMBH, and Other Prominent Player
Customization Scope Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.
Pricing And Available Payment Methods Explore pricing alternatives that are customized to your particular study requirements.

Segmentation of Pre-Fillable Syringe Closures and Accessories Market

Global Pre-Fillable Syringe Closures and Accessories Market, by Product

  • Glass Syringes
    • Plunger Stoppers
    • Plunger Rods
    • Backstops
    • Needle shields
    • Closure systems for luer lock syringes
    • Closure systems for luer cones syringes
    • Safety System/Component
  • Polymer Syringes
    • Plunger Stoppers
    • Plunger Rods
    • Backstops 

 pre fillable syringe

Global Pre-Fillable Syringe Closures and Accessories Market, by End-user

  • Pharmaceutical & Biotechnology Companies
  • Contract Research & Manufacturing Organizations
  • Other Institutes

Global Pre-Fillable Syringe Closures and Accessories Market, by Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

North America Pre-Fillable Syringe Closures and Accessories Market, by Country

  • U.S.
  • Canada

Europe Pre-Fillable Syringe Closures and Accessories Market, by Country

  • Germany
  • France
  • Italy
  • Spain
  • Russia
  • Rest of Europe

Asia Pacific Pre-Fillable Syringe Closures and Accessories Market, by Country

  • India
  • China
  • Japan
  • South Korea
  • Australia & New Zealand

Latin America Pre-Fillable Syringe Closures and Accessories Market, by Country

  • Brazil
  • Mexico
  • Rest of Latin America

Middle East & Africa Pre-Fillable Syringe Closures and Accessories Market, by Country

  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Landscape

  • Company Overview
  • Financial Performance
  • Key Development

Latest Strategic Developments

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Research Design and Approach

This study employed a multi-step, mixed-method research approach that integrates:

  • Secondary research
  • Primary research
  • Data triangulation
  • Hybrid top-down and bottom-up modelling
  • Forecasting and scenario analysis

This approach ensures a balanced and validated understanding of both macro- and micro-level market factors influencing the market.

Secondary Research

Secondary research for this study involved the collection, review, and analysis of publicly available and paid data sources to build the initial fact base, understand historical market behaviour, identify data gaps, and refine the hypotheses for primary research.

Sources Consulted

Secondary data for the market study was gathered from multiple credible sources, including:

  • Government databases, regulatory bodies, and public institutions
  • International organizations (WHO, OECD, IMF, World Bank, etc.)
  • Commercial and paid databases
  • Industry associations, trade publications, and technical journals
  • Company annual reports, investor presentations, press releases, and SEC filings
  • Academic research papers, patents, and scientific literature
  • Previous market research publications and syndicated reports

These sources were used to compile historical data, market volumes/prices, industry trends, technological developments, and competitive insights.

Secondary Research

Primary Research

Primary research was conducted to validate secondary data, understand real-time market dynamics, capture price points and adoption trends, and verify the assumptions used in the market modelling.

Stakeholders Interviewed

Primary interviews for this study involved:

  • Manufacturers and suppliers in the market value chain
  • Distributors, channel partners, and integrators
  • End-users / customers (e.g., hospitals, labs, enterprises, consumers, etc., depending on the market)
  • Industry experts, technology specialists, consultants, and regulatory professionals
  • Senior executives (CEOs, CTOs, VPs, Directors) and product managers

Interview Process

Interviews were conducted via:

  • Structured and semi-structured questionnaires
  • Telephonic and video interactions
  • Email correspondences
  • Expert consultation sessions

Primary insights were incorporated into demand modelling, pricing analysis, technology evaluation, and market share estimation.

Data Processing, Normalization, and Validation

All collected data were processed and normalized to ensure consistency and comparability across regions and time frames.

The data validation process included:

  • Standardization of units (currency conversions, volume units, inflation adjustments)
  • Cross-verification of data points across multiple secondary sources
  • Normalization of inconsistent datasets
  • Identification and resolution of data gaps
  • Outlier detection and removal through algorithmic and manual checks
  • Plausibility and coherence checks across segments and geographies

This ensured that the dataset used for modelling was clean, robust, and reliable.

Market Size Estimation and Data Triangulation

Bottom-Up Approach

The bottom-up approach involved aggregating segment-level data, such as:

  • Company revenues
  • Product-level sales
  • Installed base/usage volumes
  • Adoption and penetration rates
  • Pricing analysis

This method was primarily used when detailed micro-level market data were available.

Bottom Up Approach

Top-Down Approach

The top-down approach used macro-level indicators:

  • Parent market benchmarks
  • Global/regional industry trends
  • Economic indicators (GDP, demographics, spending patterns)
  • Penetration and usage ratios

This approach was used for segments where granular data were limited or inconsistent.

Hybrid Triangulation Approach

To ensure accuracy, a triangulated hybrid model was used. This included:

  • Reconciling top-down and bottom-up estimates
  • Cross-checking revenues, volumes, and pricing assumptions
  • Incorporating expert insights to validate segment splits and adoption rates

This multi-angle validation yielded the final market size.

Forecasting Framework and Scenario Modelling

Market forecasts were developed using a combination of time-series modelling, adoption curve analysis, and driver-based forecasting tools.

Forecasting Methods

  • Time-series modelling
  • S-curve and diffusion models (for emerging technologies)
  • Driver-based forecasting (GDP, disposable income, adoption rates, regulatory changes)
  • Price elasticity models
  • Market maturity and lifecycle-based projections

Scenario Analysis

Given inherent uncertainties, three scenarios were constructed:

  • Base-Case Scenario: Expected trajectory under current conditions
  • Optimistic Scenario: High adoption, favourable regulation, strong economic tailwinds
  • Conservative Scenario: Slow adoption, regulatory delays, economic constraints

Sensitivity testing was conducted on key variables, including pricing, demand elasticity, and regional adoption.

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Frequently Asked Questions

Significant market players are BD (Becton, Dickinson and Company), Dätwyler Holding Inc., Gerresheimer AG, West Pharmaceutical Services, Inc., AptarGr

The Pre-Fillable Syringe Closures and Accessories Market Size is valued at USD 2188.38 Million in 2023 and is predicted to reach USD 4,848.54 Million

The Pre-Fillable Syringe Closures and Accessories Market is expected to grow at a 10.57% CAGR during the forecast period for 2024-2031.
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