The ADME Toxicology Testing Market Size is valued at USD 3.82 Bn in 2023 and is predicted to reach USD 7.12 Bn by the year 2031 at an 8.3% CAGR during the forecast period for 2024-2031.
ADME, which stands for Absorption, Distribution, Metabolism, and Excretion, refers to the studies designed to investigate how a chemical, such as a drug compound, is processed by a living organism. These studies help determine how the drug is absorbed into the bloodstream, distributed throughout the body, metabolized into different substances, and excreted. Toxicology tests, which are often part of this process, provide insights into the potential adverse effects of the drug. When combined, these studies yield the acronym ADMET, which encompasses both the pharmacokinetic and toxicological evaluation necessary for assessing the safety and efficacy of new drug candidates.
ADME toxicology testing helps to identify drugs or chemicals that are likely to be toxic, have poor bioavailability (i.e., they are not well absorbed by the body), or interact with other drugs. Additionally, ADME testing aids in optimizing the dosing of drugs. By addressing these critical aspects, ADME toxicology testing ensures that new drugs are safe and effective for patients. It includes studying acute, chronic, and sub-chronic toxicity, genotoxicity, carcinogenicity, reproductive and developmental toxicity, and other specific toxicological endpoints.
The application of ADME toxicology testing in drug development and chemical safety assessment is multifaceted and crucial. It is used to determine drugs or chemicals likely to be toxic, preventing potential harm to patients and identify potential interactions with other drugs, minimizing adverse effects.
The is segmented based on the type of services, type of assays, type of molecule, end user, and therapeutic areas. By Type of Services segmented into absorption, distribution, metabolism, and excretion. Based on the Type of Assays segmented into batch / fed-batch, continuous. Therapeutic Areas, the market is categorized into blood disorder, cardiovascular disorder, gastrointestinal and vascular disorder, hormonal disorder, infectious diseases, immunological disorders, mental disorders, metabolic disorders, neurological disorders, oncology disorders, respiratory disorders. Type of Molecule segmented into biologics, small molecules. End User segmented into pharmaceutical and biotechnology companies, academic / research institutes.
Based on Therapeutic Areas, the market is categorized into blood disorder, cardiovascular disorder, gastrointestinal and vascular disorder, hormonal disorder, infectious diseases, immunological disorders, mental disorders, metabolic disorders, neurological disorders, oncology disorders, respiratory disorders. Among these, the oncology disorders segment is expected to have the highest growth rate during the forecast period. This is because cancer drug development is a highly active and rapidly evolving area of research and development. Oncology drugs often require extensive ADME testing to ensure they are effectively absorbed, distributed, metabolized, and excreted, as well as to understand their potential toxicological effects. The high prevalence and significant clinical need for effective cancer treatments drive substantial investment and focus in this segment, leading it to dominate the ADME toxicology testing market.
Based on type of Assay, the segment divided into batch / fed-batch, continuous form. Among these, the batch / fed-batch segment dominates the market during the forecast period. Batch and fed-batch processes are more commonly used in the production and testing of pharmaceuticals, including ADME toxicology studies, because they offer greater control over experimental conditions and are well-suited to the scale of most laboratory and preclinical studies. These methods allow for precise adjustments to be made to the testing environment and are easier to manage compared to continuous processes, which are more complex and typically used for large-scale manufacturing rather than initial testing and development phases.
North America, particularly the United States, has a highly developed healthcare infrastructure that supports extensive research and development activities. The region is home to many of the world's leading pharmaceutical companies, which conduct extensive drug development and testing. North America is at the forefront of adopting advanced technologies and methodologies in ADME toxicology testing, improving efficiency and outcomes. The availability of a highly skilled workforce in biomedical and pharmaceutical sciences enhances the capacity for high-quality ADME testing.
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Report Attribute |
Specifications |
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Market Size Value In 2023 |
USD 3.82 Bn |
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Revenue Forecast In 2031 |
USD 7.12 Bn |
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Growth Rate CAGR |
CAGR of 8.3% from 2024 to 2031 |
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Quantitative Units |
Representation of revenue in US$ Bn and CAGR from 2024 to 2031 |
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Historic Year |
2019 to 2023 |
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Forecast Year |
2024-2031 |
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Report Coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
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Segments Covered |
By Type of Services, Type of Assays, Type of Molecule, End User, Therapeutic Areas |
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Regional Scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
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Country Scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; The UK; France; Italy; Spain; China; Japan; India; South Korea; Southeast Asia; South Korea; South East Asia |
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Competitive Landscape |
Thermo Fisher Scientific Inc., Promega Corporation, Agilent Technologies, Inc., Charles River Laboratories, RTI International., Eurofins Scientific, Evotec, Galapagos, Tecan Group, GVK Biosciences, Pharmaron, Pharmaceutical Product Development (PPD), Sai Life Sciences, Shanghai Medicilon, Syngene International |
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Customization Scope |
Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape. |
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Pricing and Available Payment Methods |
Explore pricing alternatives that are customized to your particular study requirements. |
Global ADME Toxicology Testing Market -Type of Services
Global ADME Toxicology Testing Market – Type of Assays
Global ADME Toxicology Testing Market – Type of Molecules
Global ADME Toxicology Testing Market – End Users
Global ADME Toxicology Testing Market – Therapeutic Areas
Global ADME Toxicology Testing Market – By Region
North America-
Europe-
Asia-Pacific-
Latin America-
Middle East & Africa-
InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.
Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.
Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.
Secondary research
The secondary research sources that are typically mentioned to include, but are not limited to:
The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista
Primary Research:
Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies
The contributors who typically take part in such a course include, but are not limited to:
Data Modeling and Analysis:
In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.
The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.
To know more about the research methodology used for this study, kindly contact us/click here.
