Global DNases, ligases, and RNA Polymerases Market

Report ID : 1439 | Published : 2022-11-11 | Pages: | Format: PDF/EXCEL

The market size of the Global DNases, ligases, and RNA polymerases market in the year 2021 is valued at 601.53 million and is predicted to reach 1150.02 million by the year 2030 at an 7.72% CAGR during the forecast period.

The usage of ligases in next-generation sequencing (NGS), polymerase chain reaction, mutation detection, cloning, therapeutic target, and protein engineering has considerably expanded. Utilizing PCR technologies for biological applications requires DNA polymerase. The market is propelled by the increasing importance of diagnosing genetic abnormalities, infectious diseases, and the rising incidence of cancer worldwide. The rising incidences of chronic illnesses like cancer among people are fostering interest in and need for novel therapeutic approaches that will enhance the market growth. Moreover, among the various forms of DNA manipulation operations, new protein engineering techniques are employed to produce artificial or mutant DNA polymerases, many of which are suitable for industry-specific objectives. Throughout the evaluation period, this will continue to be a significant driving force for the DNases, ligases, and RNA polymerases market. However, the market is projected to be restricted by the enzyme's high sensitivity to ligase concentration, DNA concentration, temperature, and buffer composition. The market benefited from the spread of COVID-19. The demand for ligases enzyme increased due to the sudden pandemic crisis. The need for ligases enzyme has increased due to the biotechnology and pharmaceutical industries. The presence of comparatively inexpensive possible alternatives and the high cost of reagents are expected to restrain market expansion over the forecast period. The development of DNA polymerases is anticipated to be influenced by the quickly growing use of DNA polymerases in molecular diagnostics and point-of-care kits. With the rising investments in the life sciences, more DNA polymerases' applications in epigenetics research are anticipated to support revenue growth in the global market.

Market Segmentation:

The DNases, ligases, and RNA polymerases market is segmented on the basis of DNases application, ligases application and RNA applications. Based on DNase applications, the market is segmented as biopharmaceutical processing and other applications. By ligases application, the market is segmented into oligonucleotide synthesis and other applications. By RNA applications, the market is segmented into mRNA Production and other applications.

Based on the product, the biopharmaceutical processing segment significantly contributes to the DNases, ligases, and RNA polymerases market.

Biopharmaceutical processing will hold a major share in the global DNases, ligases, and RNA polymerases market. This is ascribed to elements like a rise in pharmaceutical DNA enzymes, which are crucial for treating various chronic illnesses and gastrointestinal problems. Additionally, advancements in the biotechnology and healthcare industries, such as the introduction of genetic and protein programming, have aided in the expansion of protein technologies, which is anticipated to present profitable growth prospects throughout the forecast period.

The oligonucleotide synthesis segment witnessed growth at a rapid rate.

The oligonucleotide synthesis segment is projected to grow rapidly in the global DNases, ligases, and RNA polymerases market. An essential instrument in molecular biology is oligonucleotide synthesis, the biological production of nucleic acids. Opportunities for synthetic oligonucleotides include the diagnosis of infectious and genetic illnesses, the treatment of diseases, and the development of novel drugs. One of the most recent phases of a project-based organization in oligonucleotide production offers a cost liability for companies with 12 oligonucleotide pharmaceuticals entering the ligases market and more than hundreds in preclinical development and clinical trials, especially in countries such as the US, Germany, and UK, China, and India.

In the region, the North America DNases, ligases, and RNA polymerases market holds a significant revenue share.

The North American DNases, ligases, and RNA polymerases market is expected to register the highest market share in revenue shortly. Easy availability of money and investments in state-of-the-art medical infrastructure create much potential for market expansion in the United States. Additionally, many contract manufacturing and bioprocess companies in the United States will help the market expand over time. The country will prosper due to investments in creating generic biologics after the patents on patented medicines expire. Furthermore, other innovative mRNA-based vaccines targeting a wide range of malignancies are in various phases of research. Infectious illness outbreaks will fuel market expansion during the forecasted timeframe.

In addition, Asia Pacific is projected to increase in the global DNases, ligases, and RNA polymerases market. This region's polymerase market will grow more quickly due to the globalization of the contract manufacturing industry in Japan, as well as strategic acquisitions and partnerships involving biologics goods. It is anticipated that molecular diagnostic tools, particularly enzyme-based solutions, will acquire recognition due to the increased number of patients needing long-term care. The market expansion is fueled by these encouraging trends in the Asia Pacific region.

Competitive Landscape

Some of the major key players in the DNases, ligases, and RNA polymerases market are Merck KGaA/ Sigma Aldrich; Takara Bio; Calzyme; Thermo Fisher Scientific; Promega Corporation; QIAGEN; Agilent Technologies; RayBiotech; New England Biolabs; and Abnova Corporation. Thermo Fisher Scientific; New England Biolabs; RayBiotech; Agilent Technologies; ABclonal Technology; BioVision; Promega Corporation; MBL International; Blirt; and MyBioSource. BPS Bioscience, Inc.; Novus Biologicals; Sino Biological, Inc.; MyBioSource; RayBiotech; New England Biolabs; Thermo Fisher Scientific; Biorbyt; Agilent Technologies; and Promega Corporation.

Chapter 1. Methodology and Scope

1.1. Research Methodology

1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global DNases, Ligases, And RNA Polymerases Market Snapshot

Chapter 4. Global DNases, Ligases, And RNA Polymerases Market Variables, Trends & Scope

4.1. Market Segmentation & Scope

4.2. Drivers

4.3. Challenges

4.4. Trends

4.5. Investment and Funding Analysis

4.6. Industry Analysis – Porter’s Five Forces Analysis

4.7. Competitive Landscape & Market Share Analysis

4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: by DNases Application Estimates & Trend Analysis

5.1. by DNases Application & Market Share, 2019 & 2030

5.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2030 for the following by DNases Application:

5.2.1. Biopharmaceutical Processing

5.2.2. Other applications

Chapter 6. Market Segmentation 2: by Ligases Application Estimates & Trend Analysis

6.1. by Ligases Application & Market Share, 2019 & 2030

6.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2030 for the following by Ligases Application:

6.2.1. Oligonucleotide Synthesis

6.2.2. Other Applications

Chapter 7. Market Segmentation 3: by RNA Polymerase Application Estimates & Trend Analysis

7.1. by RNA Polymerase Application & Market Share, 2019 & 2030

7.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2030 for the following by RNA Polymerase Application:

7.2.1. mRNA Production

7.2.2. Other Applications

Chapter 8. DNases, Ligases, And RNA Polymerases Market Segmentation 4: Regional Estimates & Trend Analysis

8.1. North America

8.1.1. North America DNases, Ligases, And RNA Polymerases Market Revenue (US$ Million) Estimates and Forecasts by DNases Application, 2022-2030

8.1.2. North America DNases, Ligases, And RNA Polymerases Market Revenue (US$ Million) Estimates and Forecasts by Ligases Application, 2022-2030

8.1.3. North America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2022-2030

8.1.4. North America DNases, Ligases, And RNA Polymerases Market Revenue (US$ Million) Estimates and Forecasts by country, 2022-2030

8.2. Europe

8.2.1. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2022-2030

8.2.2. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2022-2030

8.2.3. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2022-2030

8.2.4. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2022-2030

8.3. Asia Pacific

8.3.1. Asia Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2022-2030

8.3.2. Asia Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2022-2030

8.3.3. Asia-Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2022-2030

8.3.4. Asia Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2022-2030

8.4. Latin America

8.4.1. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2022-2030

8.4.2. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2022-2030

8.4.3. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2022-2030

8.4.4. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2022-2030

8.5. Middle East & Africa

8.5.1. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2022-2030

8.5.2. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2022-2030

8.5.3. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2022-2030

8.5.4. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2022-2030

Chapter 9. Competitive Landscape

9.1. Major Mergers and Acquisitions/Strategic Alliances

9.2. Company Profiles

9.2.1. Merck Kagan/ Sigma Aldrich

9.2.2. Takara Bio

9.2.3. Cal zyme

9.2.4. Thermos Fisher Scientific

9.2.5. Promega Corporation

9.2.6. QIAGEN

9.2.7. Agilent Technologies

9.2.8. Ray Biotech

9.2.9. New England Biolabs

9.2.10. Above Corporation

9.2.11. Thermos Fisher Scientific

9.2.12. New England Biolabs

9.2.13. Ray Biotech

9.2.14. Agilent Technologies

9.2.15. Aclinal Technology

9.2.16. Bio Vision

9.2.17. Promega Corporation

9.2.18. MBL International

9.2.19. Blart

9.2.20. My BioSource

9.2.21. BPS Bioscience, Inc.

9.2.22. Novus Biologicals

9.2.23. Sino Biological, Inc

9.2.24. My BioSource

9.2.25. Ray Biotech

9.2.26. New England Biolabs

9.2.27. Thermos Fisher Scientific

9.2.28. Biorobot

9.2.29. Agilent Technologies

9.2.30. Promega Corporation

9.2.31. Other Prominent Players

By DNases Application

  • Biopharmaceutical Processing
  • Other applications

By Ligases Application

  • Oligonucleotide Synthesis
  • Other Applications

By RNA Polymerase Application

  • mRNA Production
  • Other Applications

By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

Need Complete Report ?
Our Clients