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Global DNases, ligases, and RNA Polymerases Market

DNases, ligases, and RNA Polymerases Market Size, Share & Trends Analysis Report By DNases Application (Biopharmaceutical Processing, Other applications), By DNases Application, By RNA Polymerase Application, By Region, And By Segment Forecasts, 2024-2031

Report ID : 1439 | Published : 2024-04-20 | Pages: 190 | Format: PDF/EXCEL

The DNases, ligases, and RNA Polymerases Market Size is valued at USD 681.07 Million in 2023 and is predicted to reach USD 1,326.32 Million by the year 2031 at an 8.83 % CAGR during the forecast period for 2024-2031.

Key Industry Insights & Findings from the Report:

  • The rise of RNA-based therapeutics, including mRNA vaccines and RNA interference (RNAi) therapies, presents opportunities for RNA polymerases in synthesizing therapeutic RNA molecules.
  • The increasing emphasis on biotechnological and life sciences research activities fuels the demand for enzymes such as DNases, ligases, and RNA polymerases.
  • North America dominated the market and accounted for a revenue share of global revenue in 2023.
  • The economic feasibility of enzyme production and its impact on overall research costs can be a limiting factor.

 DNA

The usage of ligases in next-generation sequencing (NGS), polymerase chain reaction, mutation detection, cloning, therapeutic target, and protein engineering has considerably expanded. Utilizing PCR technologies for biological applications requires DNA polymerase. The market is propelled by the increasing importance of diagnosing genetic abnormalities, infectious diseases, and the rising incidence of cancer worldwide. The rising incidences of chronic illnesses like cancer among people are fostering interest in and need for novel therapeutic approaches that will enhance the market growth. Moreover, among the various forms of DNA manipulation operations, new protein engineering techniques are employed to produce artificial or mutant DNA polymerases, many of which are suitable for industry-specific objectives. Throughout the evaluation period, this will continue to be a significant driving force for the DNases, ligases, and RNA polymerases market.

However, the market is projected to be restricted by the enzyme's high sensitivity to ligase concentration, DNA concentration, temperature, and buffer composition. The market benefited from the spread of COVID-19. The demand for ligases enzyme increased due to the sudden pandemic crisis. The need for ligases enzyme has increased due to the biotechnology and pharmaceutical industries. The presence of comparatively inexpensive possible alternatives and the high cost of reagents are expected to restrain market expansion over the forecast period. The development of DNA polymerases is anticipated to be influenced by the quickly growing use of DNA polymerases in molecular diagnostics and point-of-care kits. With the rising investments in the life sciences, more DNA polymerases' applications in epigenetics research are anticipated to support revenue growth in the global market.

Competitive Landscape

Some Major Key Players In The DNases, ligases, and RNA Polymerases Market:

  • Merck KGaA/ Sigma Aldrich;
  • Takara Bio;
  • Calzyme;
  • Thermo Fisher Scientific;
  • Promega Corporation;
  • QIAGEN;
  • Agilent Technologies;
  • RayBiotech;
  • New England Biolabs;
  • Abnova Corporation.
  • ABclonal Technology;
  • BioVision;
  • MBL International;
  • Blirt;
  • BPS Bioscience, Inc.;
  • Novus Biologicals;
  • Sino Biological, Inc.;
  • MyBioSource;
  • Biorbyt

Market Segmentation:

The DNases, ligases, and RNA polymerases market is segmented on the basis of DNases application, ligases application and RNA applications. Based on DNase applications, the market is segmented as biopharmaceutical processing and other applications. By ligases application, the market is segmented into oligonucleotide synthesis and other applications. By RNA applications, the market is segmented into mRNA Production and other applications.

Based On The DNases application, The Biopharmaceutical Processing Segment Significantly Contributes To The Dnases, Ligases, And RNA Polymerases Market.

Biopharmaceutical processing will hold a major share in the global DNases, ligases, and RNA polymerases market. This is ascribed to elements like a rise in pharmaceutical DNA enzymes, which are crucial for treating various chronic illnesses and gastrointestinal problems. Additionally, advancements in the biotechnology and healthcare industries, such as the introduction of genetic and protein programming, have aided in the expansion of protein technologies, which is anticipated to present profitable growth prospects throughout the forecast period.

The Oligonucleotide Synthesis Segment Witnessed Growth At A Rapid Rate.

The oligonucleotide synthesis segment is projected to grow rapidly in the global DNases, ligases, and RNA polymerases market. An essential instrument in molecular biology is oligonucleotide synthesis, the biological production of nucleic acids. Opportunities for synthetic oligonucleotides include the diagnosis of infectious and genetic illnesses, the treatment of diseases, and the development of novel drugs. One of the most recent phases of a project-based organization in oligonucleotide production offers a cost liability for companies with 12 oligonucleotide pharmaceuticals entering the ligases market and more than hundreds in preclinical development and clinical trials, especially in countries such as the US, Germany, and UK, China, and India.

In The Region, The North America Dnases, Ligases, And RNA Polymerases Market Holds A Significant Revenue Share.

The North American DNases, ligases, and RNA polymerases market is expected to register the highest market share in revenue shortly. Easy availability of money and investments in state-of-the-art medical infrastructure create much potential for market expansion in the United States. Additionally, many contract manufacturing and bioprocess companies in the United States will help the market expand over time. The country will prosper due to investments in creating generic biologics after the patents on patented medicines expire. Furthermore, other innovative mRNA-based vaccines targeting a wide range of malignancies are in various phases of research. Infectious illness outbreaks will fuel market expansion during the forecasted timeframe.

In addition, Asia Pacific is projected to increase in the global DNases, ligases, and RNA polymerases market. This region's polymerase market will grow more quickly due to the globalization of the contract manufacturing industry in Japan, as well as strategic acquisitions and partnerships involving biologics goods. It is anticipated that molecular diagnostic tools, particularly enzyme-based solutions, will acquire recognition due to the increased number of patients needing long-term care. The market expansion is fueled by these encouraging trends in the Asia Pacific region.

Recent Developments:

  • In May 2023, QIAGEN introduced individual products containing its premium enzymes, granting industrial and scientific clients around the world the ability to personalize their assays and workflows. By providing automation and bioinformatics solutions in addition to specialized enzymes and sample preparation solutions, QIAGEN evolved into a one-stop shop for all research requirements.

DNases, ligases, and RNA Polymerases Market Report Scope

Report Attribute

Specifications

Market Size Value In 2023

USD 681.07 Million

Revenue Forecast In 2031

USD 1,326.32 Million

Growth Rate CAGR

CAGR of 8.83 % from 2024 to 2031

Quantitative Units

Representation of revenue in US$ Million and CAGR from 2024 to 2031

Historic Year

2019 to 2023

Forecast Year

2024-2031

Report Coverage

The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends

Segments Covered

By DNases Application, By DNases Application, By RNA Polymerase Application

Regional Scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country Scope

U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico ;The UK; France; Italy; Spain; China; Japan; India; South Korea; South East Asia; South Korea; South East Asia

Competitive Landscape

Merck KGaA/ Sigma Aldrich; Takara Bio; Calzyme; Thermo Fisher Scientific; QIAGEN; Agilent Technologies; RayBiotech; Abnova Corporation. Thermo Fisher Scientific; New England Biolabs; Agilent Technologies; ABclonal Technology; BioVision; Promega Corporation; MBL International; Blirt; and MyBioSource. BPS Bioscience, Inc.; Novus Biologicals; Sino Biological, Inc.; MyBioSource; RayBiotech; New England Biolabs;

Customization Scope

Free customization report with the procurement of the report, Modifications to the regional and segment scope. Particular Geographic competitive landscape.

Pricing And Available Payment Methods

Explore pricing alternatives that are customized to your particular study requirements.

 

Chapter 1. Methodology and Scope

1.1. Research Methodology

1.2. Research Scope & Assumptions

Chapter 2. Executive Summary

Chapter 3. Global DNases, Ligases, And RNA Polymerases Market Snapshot

Chapter 4. Global DNases, Ligases, And RNA Polymerases Market Variables, Trends & Scope

4.1. Market Segmentation & Scope

4.2. Drivers

4.3. Challenges

4.4. Trends

4.5. Investment and Funding Analysis

4.6. Industry Analysis – Porter’s Five Forces Analysis

4.7. Competitive Landscape & Market Share Analysis

4.8. Impact of Covid-19 Analysis

Chapter 5. Market Segmentation 1: by DNases Application Estimates & Trend Analysis

5.1. by DNases Application & Market Share, 2019 & 2031

5.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by DNases Application:

5.2.1. Biopharmaceutical Processing

5.2.2. Other applications

Chapter 6. Market Segmentation 2: by Ligases Application Estimates & Trend Analysis

6.1. by Ligases Application & Market Share, 2019 & 2031

6.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by Ligases Application:

6.2.1. Oligonucleotide Synthesis

6.2.2. Other Applications

Chapter 7. Market Segmentation 3: by RNA Polymerase Application Estimates & Trend Analysis

7.1. by RNA Polymerase Application & Market Share, 2019 & 2031

7.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by RNA Polymerase Application:

7.2.1. mRNA Production

7.2.2. Other Applications

Chapter 8. DNases, Ligases, And RNA Polymerases Market Segmentation 4: Regional Estimates & Trend Analysis

8.1. North America

8.1.1. North America DNases, Ligases, And RNA Polymerases Market Revenue (US$ Million) Estimates and Forecasts by DNases Application, 2024-2031

8.1.2. North America DNases, Ligases, And RNA Polymerases Market Revenue (US$ Million) Estimates and Forecasts by Ligases Application, 2024-2031

8.1.3. North America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2024-2031

8.1.4. North America DNases, Ligases, And RNA Polymerases Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031

8.2. Europe

8.2.1. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2024-2031

8.2.2. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2024-2031

8.2.3. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2024-2031

8.2.4. Europe DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2024-2031

8.3. Asia Pacific

8.3.1. Asia Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2024-2031

8.3.2. Asia Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2024-2031

8.3.3. Asia-Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2024-2031

8.3.4. Asia Pacific DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2024-2031

8.4. Latin America

8.4.1. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2024-2031

8.4.2. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2024-2031

8.4.3. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2024-2031

8.4.4. Latin America DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2024-2031

8.5. Middle East & Africa

8.5.1. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by DNases Application, 2024-2031

8.5.2. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by Ligases Application, 2024-2031

8.5.3. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by RNA Polymerase Application, 2024-2031

8.5.4. Middle East & Africa DNases, Ligases, And RNA Polymerases Market revenue (US$ Million) by country, 2024-2031

Chapter 9. Competitive Landscape

9.1. Major Mergers and Acquisitions/Strategic Alliances

9.2. Company Profiles

9.2.1. Merck Kagan/ Sigma Aldrich

9.2.2. Takara Bio

9.2.3. Cal zyme

9.2.4. Thermos Fisher Scientific

9.2.5. Promega Corporation

9.2.6. QIAGEN

9.2.7. Agilent Technologies

9.2.8. Ray Biotech

9.2.9. New England Biolabs

9.2.10. Above Corporation

9.2.11. Thermos Fisher Scientific

9.2.12. New England Biolabs

9.2.13. Ray Biotech

9.2.14. Agilent Technologies

9.2.15. Aclinal Technology

9.2.16. Bio Vision

9.2.17. Promega Corporation

9.2.18. MBL International

9.2.19. Blart

9.2.20. My BioSource

9.2.21. BPS Bioscience, Inc.

9.2.22. Novus Biologicals

9.2.23. Sino Biological, Inc

9.2.24. My BioSource

9.2.25. Ray Biotech

9.2.26. New England Biolabs

9.2.27. Thermos Fisher Scientific

9.2.28. Biorobot

9.2.29. Agilent Technologies

9.2.30. Promega Corporation

9.2.31. Other Prominent Players

Segmentation of DNases, ligases, and RNA Polymerases Market:

By DNases Application

  • Biopharmaceutical Processing
  • Other applications

DNA

By Ligases Application

  • Oligonucleotide Synthesis
  • Other Applications

By RNA Polymerase Application

  • mRNA Production
  • Other Applications

By Region-

North America-

  • The US
  • Canada
  • Mexico

Europe-

  • Germany
  • The UK
  • France
  • Italy
  • Spain
  • Rest of Europe

Asia-Pacific-

  • China
  • Japan
  • India
  • South Korea
  • Southeast Asia
  • Rest of Asia Pacific

Latin America-

  • Brazil
  • Argentina
  • Rest of Latin America

 Middle East & Africa-

  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.

Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.

Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.

Secondary research

The secondary research sources that are typically mentioned to include, but are not limited to:

  • Company websites, financial reports, annual reports, investor presentations, broker reports, and SEC filings.
  • External and internal proprietary databases, regulatory databases, and relevant patent analysis
  • Statistical databases, National government documents, and market reports
  • Press releases, news articles, and webcasts specific to the companies operating in the market

The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista

Primary Research:

Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies

The contributors who typically take part in such a course include, but are not limited to: 

  • Industry participants: CEOs, CBO, CMO, VPs, marketing/ type managers, corporate strategy managers, and national sales managers, technical personnel, purchasing managers, resellers, and distributors.
  • Outside experts: Valuation experts, Investment bankers, research analysts specializing in specific markets
  • Key opinion leaders (KOLs) specializing in unique areas corresponding to various industry verticals
  • End-users: Vary mainly depending upon the market

Data Modeling and Analysis:

In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.

The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.

To know more about the research methodology used for this study, kindly contact us/click here.

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Frequently Asked Questions

How big is the DNases, ligases, and RNA Polymerases Market Size?

The DNases, ligases, and RNA Polymerases Market is expected to grow at an 8.83% CAGR during the forecast period for 2024-2031.

Merck KGaA/ Sigma Aldrich; Takara Bio; Calzyme; Thermo Fisher Scientific; QIAGEN; Agilent Technologies; RayBiotech; Abnova Corporation. Thermo Fisher

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