The market size of the Global Circulating Cell-Free DNA (ccfDNA) Diagnostics Market in the year 2021 is valued at 4.80 billion and is predicted to reach 23.06 billion by the year 2030 at an 19.2% CAGR during the forecast period.
Circulating cell-free DNA is defined as DNA fragments released in the bloodstream for essential and chronic disorders. ccfDNA, also known as circulating DNA (ctDNA), has recently gained popularity as a non-invasive illness biomarker. The scientific community's interest in therapeutic applications of ctDNA continues to grow at an exponential rate, fueling its attractiveness as a viable target in a wide range of study domains. One of the primary drivers of the Global Circulating Cell-Free DNA (ccfDNA) Diagnostics Market is the growing concern for early cancer detection. Other drivers include the success of NIPTs, increased cancer prevalence, and an increase in research and development initiatives to investigate the usefulness of circulating biomarkers in disease diagnosis. Furthermore, advances in molecular technology are promoting the exploration of cfDNA as a possible tool for the creation of minimally invasive diagnostics. The use of cfDNA-based diagnostics enhances both informed clinical decision-making and patient outcomes.
However, lack of standardization, poor reimbursement policies, and legal and regulatory restrictions are among the factors impeding market expansion. The dearth of awareness among people in underdeveloped nations is also hindering market expansion.
The Circulating Cell-Free DNA (ccfDNA) Diagnostics market is segmented on the basis of components, Application and end-users. Based on Application, the market is segmented into Non-invasive Prenatal Testing, Cancer Diagnostics, and Others. Based on End-Use, the market is segmented into Hospitals & Prenatal Clinics, Diagnostic Centers, Academic & Government Institutes, Biotechnology & Pharmaceutical Companies.
Based on Non-Invasive Prenatal Testing, the Virtual Reality Headset segment is accounted as a major contributor in the Circulating Cell-Free DNA (ccfDNA) Diagnostics market.
The market for circulating cell-free DNA (ccfDNA) diagnostics is expected to be dominated by non-invasive prenatal testing in terms of revenue. The dominance of this market has been aided by the popularity of non-invasive tests based on cfDNA. Furthermore, the segment is being driven by increased medical coverage for NIPTs. A non-invasive DNA testing process without the hazards associated with amniocentesis or CVS (chorionic villus sample). One of the major aspects driving this segment's revenue growth is increasing knowledge of the procedure's benefits. On the other hand, the category for cancer diagnostics is anticipated to develop the fastest. The main engine of segment expansion is rising investment in the creation of liquid biopsies.
Hospital & Prenatal Clinics segment witnessed growth at a rapid rate
The hospitals & prenatal clinics segment is anticipated to gain the major share of the global circulating cell-free DNA (ccfDNA) diagnostics market in the forecast period. The public's understanding and acceptance of non-invasive prenatal DNA screening is growing, which has boosted this sector's income flow. Hospitals & prenatal clinics remain the leading end-users of the market due to the benefits of NIPTs, such as early risk diagnosis of chromosomal defects like down syndrome and trisomy utilizing NIPTs. However, the fastest expanding end-user of this industry is emerging to be the biotechnology and pharmaceutical industries. The primary driver of this category is the recent approval of companion diagnostics.
The North America Circulating Cell-Free DNA (ccfDNA) Diagnostics market holds a significant revenue share in the region.
The North America Circulating Cell-Free DNA (ccfDNA) Diagnostics market is likely to register a significant revenue share. Countries like Canada and the United States contribute the most to it. Because of these areas' growing economies, improved healthcare infrastructure, and rising illness prevalence, The promise of the cell-free DNA testing business has enticed numerous biotechnology and pharmaceutical companies to acquire other large companies or establish new tests. Increased rates of disorders such as chromosomal abnormalities owing to high maternal age, changing lifestyle, bad diet habits, and rising cancer prevalence, as well as increasing healthcare spending and awareness, are driving the cell-free DNA market in this area.
The key players in the Circulating Cell-Free DNA (ccfDNA) Diagnostics market have shifted their focus towards bio-based components for product manufacturing and are initiating significant strategies such as mergers, acquisitions, and joint ventures of major and domestic players to enhance product portfolio and strengthen their market footprint across the globe. Some of the major key players in the Circulating Cell-Free DNA (ccfDNA) Diagnostics market are Hoffmann-La Roche, Natera Inc., Illumina Inc., Agena Bioscience, Paragon Genomics, Thermo Fisher Scientific, Bio-Rad Laboratories, Lucence Health, and Eurofins.