The market size of the Global 3D Protein Structure Analysis market in the year 2021 is valued at 1059.56 million and is predicted to expand at a 10.6% CAGR during the forecast period. The three-dimensional arrangement of atoms determines a protein's biological function. This could be catalytic residues in an active site or how a protein interacts with others for structural or regulatory purposes. Protein structures help us understand how a protein operates, allowing us to form theories about how to alter, control, or modify it. Knowing a protein's structure could allow site-directed alterations to change function. Predict protein-binding compounds. The amino acid sequence of a protein decides the stable three-dimensional forms, or conformations, into which it folds. It is becoming increasingly apparent that the number of unique folds in proteins is significantly smaller than the total number of protein structures because X-ray crystallography and nuclear magnetic resonance (NMR) are rapidly being used to determine a multitude of different protein structures. Understanding a protein's structure and function in the cell depends on knowing its amino acid sequence. For example, following the instructions recorded in the genetic code, the collection of nucleotides that makes up a gene is first translated into a collection of amino acids. Only after taking on a three-dimensional shape, the so-called tertiary, or native structure of the protein, does the matching linear chain of amino acids become functional.
Rising emphasis on automation and miniaturisation in X-ray crystallography workflow influence the 3D protein structure analysis market growth. Also, increase in Drug Discovery and Development R&D Expenditures and Technological Advances in Protein Structure Analysis Equipment. Drug discovery makes extensive use of artificial intelligence by researchers and pharmaceutical businesses. Recently, DeepMind, the artificial intelligence unit of Google's parent firm Alphabet, has stated that it has successfully foreseen the structure of nearly every protein in the human body. In addition, they can anticipate the structure of thousands of additional proteins found in species such as mice, fruit flies, and yeast that are essential to scientific research.
The major limitations are expenditure, time, and knowledge. In order to solve structures using crystallography and nuclear magnetic resonance (NMR), one has to have received very specific training and a high level of experience. Additionally, the expense of resolving a unique structure is quite significant.
The 3D protein structure analysis market is segmented by product and end-user. The product segment comprises Consumable (X-Ray Crystallography, Nuclear Magnetic Resonance (NMR) Spectroscopy, Cryo-Electron Microscopy (Cryo-EM), Small Angle X-Ray Scattering (SAXS) ), Equipment (X-Ray Crystallography, Nuclear Magnetic Resonance (NMR) Spectroscopy, Cryo-Electron Microscopy (Cryo-EM), Small Angle X-Ray Scattering (SAXS)), and Computational Software. The second major segment is the end-user segment which includes Biopharmaceutical companies, Academic and Research institutes, and Other End-User. In which the segment of biopharmaceutical companies is the dominant market end user.
The North American market is anticipated to grow due to significant funding, collaborations, investments, and innovations for economic development and public health, as well as the region's prioritisation of using 3D protein structures for molecular research and the development of novel drugs.
The significant market companies are Merck KGaA, Bruker Corporation, JEOL Ltd., Spectris plc, Schrodinger, Inc., Thermo Fisher Scientific Inc., Molecular Dimensions, DNASTAR, Arinax Scientific Instrumentation., RosettaCommons.org, Cambridge Isotope Laboratories, Inc., HAMPTON RESEARCH CORP., Dassault Systemes, Rigaku Corporation, Jena Bioscience GmbH and other market players.
- Merck KGaA
- Bruker Corporation
- JEOL Ltd.
- Spectris plc
- Schrodinger, Inc.
- Thermo Fisher Scientific Inc.
- Molecular Dimensions
- Arinax Scientific Instrumentation.
- Cambridge Isotope Laboratories, Inc.
- HAMPTON RESEARCH CORP.
- Dassault Systemes
- Rigaku Corporation
- Jena Bioscience GmbH