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Nov 29, 2023

InsightAce Analytic | Clinical Trials , virtual clinical trials , remote clinical trials ,

What is next-generation probiotic? 

Probiotics are live microorganisms that are similar to the beneficial microorganisms found in the human gut. They are often referred to as "good" or "helpful" bacteria because they help to maintain the balance of microflora in the gut and support overall health. Probiotics are available in a variety of forms, including supplements, foods, and drinks.

The next generation probiotics industry is focused on the development and production of advanced probiotic products that offer improved efficacy and targeted health benefits. NGPs (next-generation probiotics) differ from traditional probiotics in that they are more likely to be regulated as drugs, rather than food ingredients or supplements. While traditional probiotics are primarily used to support overall health and wellness, NGPs are mainly used to treat or cure specific disease conditions in the body. As such, NGPs are considered to be therapeutics (drugs) and must be regulated under the same frameworks as pharmaceuticals. In contrast, traditional probiotics are typically classified as functional foods or supplements and are not subject to the same regulatory requirements as NGPs.

 

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Why next-generation probiotics are important?

  1. Next generation probiotics are designed to offer improved efficacy and targeted health benefits.

The improved efficacy of next-generation probiotics is due to the use of novel strains of probiotics or combination therapies that are more effective at addressing specific health conditions. For example, ne-generation probiotics may use strains of probiotics that are more resistant to stomach acid, allowing them to survive the journey through the digestive system and reach the gut more effectively. In addition, next-generation probiotics may use combination therapies that include multiple strains of probiotics and/or ther ingredients, which can offer improved health benefits compared to single-strain probiotics.
Companies that are focused on developing next-generation probiotics are investing in research to identify novel strains of probiotics or combination therapies that offer improved health benefits. They are also investing in advanced production techniques and quality control measures to ensure that their products are of high quality and consistently effective. By investing in these areas, companies can differentiate themselves from competitors and offer products that are more effective and more attractive to consumers.

 

  1. Next-generation probiotics - designed to offer targeted health benefits

Next generation probiotics may be formulated to address specific health issues, such as digestive health, immune health, or mental health. This allows for a more personalized approach to health and wellness.

Digestive health: Probiotics can help to support digestive health by maintaining the balance of microflora in the gut and helping to prevent the overgrowth of harmful bacteria. Next-generation probiotics may be formulated to support digestive health in people with conditions such as irritable bowel syndrome or inflammatory bowel disease.

Immune health: Probiotics can help to support immune health by promoting the growth of beneficial bacteria in the gut, which can help to boost the immune system. Next-generation probiotics may be formulated to support immune health in people who are prone to infections or have weakened immune systems.

Mental health: Some research suggests that probiotics may have an impact on mental health by influencing the production of neurotransmitters, such as serotonin, and by regulating the immune system. Next-generation probiotics may be formulated to support mental health in people with conditions such as anxiety or depression.

Other targeted health benefits: In addition to digestive health, immune health, and mental health, next-generation probiotics may also be formulated to address other specific health issues, such as skin health, respiratory health, and cardiovascular health.

 

  1. Provide improved stability and delivery of next-generation probiotics

The next generation probiotics industry is using novel delivery systems and formulations that can improve the stability and effectiveness of probiotics.

To improve the stability and delivery of next-generation probiotics, there are a few different approaches being adopted. One approach is the use of novel delivery systems and formulations that can protect the probiotics and enhance their delivery to the gut. This can include the use of capsules, tablets, powders, and other forms that can protect the probiotics and enhance their delivery to the gut.

Another approach is the use of technologies that can improve the stability of probiotics, such as freeze-drying or microencapsulation. These technologies can help to preserve the viability of probiotics and protect them from degradation or inactivation.

 

What are the major trends in next-generation probiotics industry?

  1. Personalized probiotics:

Personalization is a key trend in the next-generation probiotics industry, as probiotics are being developed that are tailored to an individual's specific microbiome, dietary needs, and health goals. This approach is based on the idea that each person's microbiome is unique, and that the specific strains of bacteria that make up the microbiome can have a significant impact on overall health. By developing probiotics that are tailored to the specific needs of an individual, companies are able to offer products that are more effective at supporting gut health and overall well-being.

One way that personalization is being achieved in the probiotics industry is through the use of DNA testing. By analysing an individual's DNA, companies can determine which specific strains of bacteria are present in the microbiome and tailor their probiotics accordingly. Another approach is to offer a range of probiotics that are each formulated to address specific health concerns, such as digestive issues or immune support, and allow consumers to choose the product that best meets their needs.

Overall, the trend towards personalization in the probiotics industry is driven by a growing recognition of the importance of the microbiome in overall health and the need for more targeted, effective solutions to support gut health.

There have been several major recent developments in the personalization of next-generation probiotics:

  • DNA testing: Companies are using DNA testing to analyze an individual's microbiome and tailor probiotics to the specific strains of bacteria present in the microbiome.
  • Microbiome analysis: Some companies are offering microbiome analysis services, which allow consumers to learn more about the specific strains of bacteria present in their microbiome and choose probiotics that are formulated to support the growth of beneficial bacteria.
  • Personalized probiotic blends: Some companies are offering personalized probiotic blends that are formulated based on an individual's specific health needs and goals.
  • Probiotics for specific health concerns: More and more probiotics are being developed that are formulated to address specific health concerns, such as digestive issues or immune support.
  • Probiotics for specific populations: There are also probiotics being developed that are specifically formulated for certain populations, such as children or seniors, to support their unique health needs.

There are a number of major companies that are involved in the development and production of personalised next-generation probiotics. Some examples include:

  • Ubiome: This company offers a range of DNA-based testing products that allow consumers to learn more about their microbiome and receive personalized recommendations for probiotics and other products to support gut health.
  • Viome: This company uses machine learning and DNA sequencing to analyze the microbiome and provide personalized recommendations for diet, supplements, and other lifestyle changes to support overall health.
  • DayTwo: This company offers a range of personalized probiotics based on DNA analysis and gut microbiome data.
  • Thryve: This company offers a range of personalized probiotics and other gut health products based on DNA analysis and microbiome data.
  • Seed Health: This company is focused on the development of personalized probiotics and other microbiome-based products to support overall health and well-being.
  1. Incorporating probiotics into a wide range of food and beverage

The trend towards incorporating probiotics into a wide range of food and beverage products is driven by a desire to make it easier for consumers to get their daily dose of beneficial bacteria. By adding probiotics to products that are already part of people's daily routines, such as yogurt or drinks, companies are able to make it more convenient for people to incorporate probiotics into their diets. This is especially appealing to people who may not be interested in taking supplements or who prefer to get their nutrients from food sources.

Incorporating probiotics into food and beverage products also allows companies to offer a wider range of delivery formats, such as powders, drinks, and snack bars, which can be more appealing to some consumers. For example, some people may prefer to mix a probiotic powder into their smoothies, while others may prefer to drink a probiotic-infused beverage. By offering a variety of delivery formats, companies can make it easier for people to find a product that fits their preferences and lifestyle.

Another reason why probiotics are being incorporated into food and beverage products is to provide consumers with a more enjoyable way to consume probiotics. Many people find supplements to be unappealing or inconvenient to take, and may be more likely to use a product if it is incorporated into something they already enjoy, such as a tasty yogurt or a refreshing drink. By making probiotics more enjoyable to consume, companies can encourage people to continue using their products over the long term, which can help support overall gut health.

Following are some major food and beverage product categories where probiotics are being incorporated:

  • Probiotic-infused drinks: There has been an increase in the number of probiotic-infused drinks, such as kombucha, kefir, and probiotic-infused water, being introduced to the market.
  • Probiotic-infused snack bars: Many companies are now offering snack bars that are infused with probiotics and other functional ingredients, such as prebiotics, to support gut health.
  • Probiotic-infused dairy products: Probiotics are being added to a variety of dairy products, such as yogurt and cheese, to boost the number of beneficial bacteria in these products.
  • Probiotic-infused frozen treats: Some companies are now offering probiotic-infused frozen treats, such as ice cream and popsicles, as a way to make it more enjoyable for people to consume probiotics.
  • Probiotic-infused baking mixes: There are now probiotic-infused baking mixes available, which allow people to easily incorporate probiotics into their baked goods.

There are many companies that are involved in incorporating probiotics into a wide range of food and beverage products.

Some examples include:

  • Danone: Danone is a leading global food company that produces a wide range of probiotic-infused products, including Activia yogurt, Danonino, and DanActive.
  • Yakult: Yakult is a Japanese company that produces probiotic-infused fermented milk drinks.
  • Nestle: Nestle produces a range of probiotic-infused products, including probiotic-infused water and probiotic-infused Greek yogurt under the ProNourish brand.
  • Unilever: Unilever produces a range of probiotic-infused products, including probiotic-infused ice cream and probiotic-infused smoothies.
  • General Mills: General Mills produces a range of probiotic-infused products, including Yoplait yogurt and Nature Valley granola bars.
  • PepsiCo: PepsiCo produces a range of probiotic-infused products, including Probio Energy drink and Kevita sparkling probiotic drinks.

 

Tags : Clinical Trials virtual clinical trials remote clinical trials