Global Protein Design and Engineering Market Size is valued at USD 6.4 Billion in 2024 and is predicted to reach USD 25.1 Billion by the year 2034 at a 15.0 % CAGR during the forecast period for 2025-2034.
Key Industry Insights & Findings from the Report:
The Protein engineering and designing techniques are used to identify specific amino acid sequence changes and alter this sequence for desired functional properties. Mainly computational simulation methods and experimental/molecular methods are utilized for protein engineering.
Major factors such as increasing government initiatives & funding for the development of protein designing systems, fast advancements in technologies are primarily driving the market growth. High prevalence of protein-deficient diseases, and the surging demand for protein engineering tools by biopharmaceutical companies is also expected to support the market growth. The increasing collaborations between companies operating in this market to develop new testing technologies and accelerate the resource-intensive process of protein engineering are enhancing the growth opportunities of the protein design and engineering market. For instance, in January 2021, Zymvol Biomodeling (Spain) collaborated with Aminoverse, a biotech company specializing in enzyme discovery and design, to develop custom-made alcohol dehydrogenases, an enzyme most commonly used in the flavors and fragrances and the fine chemicals industry.
However, the expensive instruments and the increasing maintenance cost of the protein engineering equipment may hinder the market growth during the estimated timeframe.
The Protein design and engineering market is segmented into the protein engineering approach used, protein types, type of application, end-users, and region. The protein engineering approach used segment comprises rational designing, directed evolution, and semi-rational designing. The rational designing segment is estimated to dominate this market during the forecast period due to its rising use in antibody and enzyme designing. The market is classified into antibodies, peptides, enzymes, vaccines, and others based on the protein types. The antibodies are expected to be the fastest-growing segment of this market, owing to their increasing applications in the medical sector. The market is grouped into therapeutics and diagnostics by type of application. The market is segmented into pharma/biotech firms, CROs (contract research organizations) & research, and academic institutes by end-users. The pharma/biotech firms are projected to hold a significant market share in the coming years due to the rising demand for advanced drug and therapy treatments to cure chronic diseases. Region-wise, the market is studied across North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa.
The Asia-Pacific market is likely to witness rapid growth during the forecast period (2019-2030) due to the well-established healthcare infrastructure, growing awareness regarding protein engineering, and the rising government efforts to develop protein designing methods.
Report Attribute |
Specifications |
Market Size Value In 2024 |
USD 6.4 Billion |
Revenue Forecast In 2034 |
USD 25.1 Billion |
Growth Rate CAGR |
CAGR of 15.0 % from 2025 to 2034 |
Quantitative Units |
Representation of revenue in US$ Bn, and CAGR from 2025 to 2034 |
Historic Year |
2021 to 2024 |
Forecast Year |
2025-2034 |
Report Coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
Segments Covered |
By Protein Engineering Approach Used, Protein Types, Type Of Application, End-users |
Regional Scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
Country Scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South East Asia; South Korea |
Competitive Landscape |
ATUM (US), Creative BioMart (US), Creative Biostructure (US), Creative Enzymes (US), Absolute Antibody (UK), EUCODIS Bioscience (Austria), Fusion Antibodies (UK), Innovagen (Sweden), ZYMVOL (Spain), Averring Biotech, EnzymeWorks (China), GeNext Genomics (India), Quantumzyme (India), and others. |
Customization Scope |
Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape. |
Pricing And Available Payment Methods |
Explore pricing alternatives that are customized to your specific requirements. |
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Protein Design and Engineering Market Snapshot
Chapter 4. Global Protein Design and Engineering Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis
Chapter 5. Market Segmentation 1: By Protein Types, Estimates & Trend Analysis
5.1. By Protein, & Market Share, 2024 & 2034
5.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Protein:
5.2.1. Antibodies
5.2.2. Peptides
5.2.3. Enzymes
5.2.4. Vaccines
5.2.5. Other Proteins
Chapter 6. Market Segmentation 2: By Type of Protein Engineering Approach Used Estimates & Trend Analysis
6.1. By Protein Engineering Approach Used & Market Share, 2024 & 2034
6.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Protein Engineering Approach Used:
6.2.1. Rational Designing
6.2.2. Directed Evolution
6.2.3. Semi-Rational Designing
Chapter 7. Market Segmentation 3: By Type of Application Estimates & Trend Analysis
7.1. By Applications & Market Share, 2024 & 2034
7.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By Applications:
7.2.1. Therapeutics
7.2.2. Diagnostics
Chapter 8. Market Segmentation 4: By End-Users Estimates & Trend Analysis
8.1. By End-Users & Market Share, 2024 & 2034
8.2. Market Size (Value US$ Mn) & Forecasts and Trend Analyses, 2021 to 2034 for the following By End-Users
8.2.1. Pharma / Biotech Firms
8.2.2. CROs and Research
8.2.3. Academic Institutes
Chapter 9. Protein Design and Engineering Market Segmentation 5: Regional Estimates & Trend Analysis
9.1. North America
9.1.1. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts By Protein, 2021-2034
9.1.2. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts By Protein Engineering Approach Used, 2021-2034
9.1.3. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts By Applications, 2021-2034
9.1.4. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.1.5. North America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by country, 2021-2034
9.2. Europe
9.2.1. Europe Protein Design and Engineering Market revenue (US$ Million) By Protein, 2021-2034
9.2.2. Europe Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, 2021-2034
9.2.3. Europe Protein Design and Engineering Market revenue (US$ Million) By Applications, 2021-2034
9.2.4. Europe Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.2.5. Europe Protein Design and Engineering Market revenue (US$ Million) by country, 2021-2034
9.3. Asia Pacific
9.3.1. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) By Protein, 2021-2034
9.3.2. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, 2021-2034
9.3.3. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) By Applications, 2021-2034
9.3.4. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.3.5. Asia Pacific Protein Design and Engineering Market revenue (US$ Million) by country, 2021-2034
9.4. Latin America
9.4.1. Latin America Protein Design and Engineering Market revenue (US$ Million) By Protein, (US$ Million) 2021-2034
9.4.2. Latin America Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, (US$ Million) 2021-2034
9.4.3. Latin America Protein Design and Engineering Market revenue (US$ Million) By Applications, (US$ Million) 2021-2034
9.4.4. Latin America Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.4.5. Latin America Protein Design and Engineering Market revenue (US$ Million) by country,2021-2034
9.5. Middle East & Africa
9.5.1. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) By Protein, (US$ Million) 2021-2034
9.5.2. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) By Protein Engineering Approach Used, (US$ Million) 2021-2034
9.5.3. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) By Applications, (US$ Million) 2021-2034
9.5.4. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) estimates and forecasts by End-Users, 2021-2034
9.5.5. Middle East & Africa Protein Design and Engineering Market revenue (US$ Million) by country, 2021-2034
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. ATUM
10.2.2. Creative BioMart
10.2.3. Creative Biostructure
10.2.4. Creative Enzymes
10.2.5. Absolute Antibody
10.2.6. EUCODIS Bioscience
10.2.7. Fusion Antibodies
10.2.8. Innovagen
10.2.9. ZYMVOL
10.2.10. Averring Biotech
10.2.11. EnzymeWorks
10.2.12. GeNext Genomics
10.2.13. Quantumzyme
10.2.14. Other Prominent Players
Global Protein Design and Engineering Market, by Type of Protein Engineering Approach Used,
Global Protein Design and Engineering Market, by Protein Types,
Global Protein Design and Engineering Market, by Type of Application,
Global Protein Design and Engineering Market, by End-Users,
Global Protein Design and Engineering Market, by Region,
North America Protein Design and Engineering Market, by Country,
Europe Protein Design and Engineering Market, by Country,
Asia Pacific Protein Design and Engineering Market, by Country,
Latin America Protein Design and Engineering Market, by Country,
Middle East & Africa Protein Design and Engineering Market, by Country,
InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.
Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.
Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.
Secondary research
The secondary research sources that are typically mentioned to include, but are not limited to:
The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista
Primary Research:
Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies
The contributors who typically take part in such a course include, but are not limited to:
Data Modeling and Analysis:
In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.
The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.
To know more about the research methodology used for this study, kindly contact us/click here.