Nucleic Acid Aptamers Market Size is valued at USD 217.3 Mn in 2023 and is predicted to reach USD 732.5 Mn by the year 2031 at a 16.7% CAGR during the forecast period for 2024-2031.
Nucleic acid aptamers are concise, individual strands of DNA or RNA that have a strong affinity for certain targets, such as proteins or tiny molecules. They are chosen via a procedure known as SELEX and are recognized for their stability, strong attraction, and minimal immune response. Aptamers find applications in diagnostics, therapies, and targeted drug delivery, providing benefits such as facile synthesis and the capability to operate in diverse settings.
The rising disposable income, improvements in aptamer creation technology, and more funding for businesses and academic institutions are all elements propelling the market forward. Additionally, more and more medical fields are looking to these tiny molecules for a variety of reasons, including the many benefits they provide over well-established antibodies.
The competitive advantages of nucleic acid aptamers have drawn the attention of many researchers, who have recently made improvements in drug delivery, target cell death, and drug purification. Researchers are motivated to develop new nucleic acid aptamers because of their small molecular size, low immunogenicity, cheap manufacturing cost, and fewer side effects in comparison to antibodies. This could lead to industry expansion. The ongoing development of novel and improved nucleic acid aptamers is propelling market expansion.
However, due to the high costs, stringent regulatory constraints, and a general lack of knowledge of nucleic acid treatments among both patients and healthcare professionals, the nucleic acid aptamers industry is expected to slow down market growth. The rapid advancement of research and development, the increased focus on the efficacy of RNA aptamers, and the surge in investment and interest in nucleic acid-based treatments for infectious diseases were all beneficial effects of the COVID-19 pandemic for the nucleic acid aptamers business. Furthermore, the demand for nucleic acid aptamers is expected to rise due to innovative treatments receiving substantial funding from pharmaceutical firms and governments.
The nucleic acid aptamers market is segmented based on type, application, indication, and end-user. By type, the market is segmented into DNA aptamer, RNA aptamer, and XNA aptamer. By the application, the market is segmented into drug delivery, anti-viral therapy, pathogen recognition, disease recognition, stem cell markers, and others. By indication, the market is segmented into viral infection, cancer, ophthalmology, and others. By end-user, the market is segmented into biopharmaceutical companies, diagnostic centres, CROs, and others.
The DNA aptamer in the nucleic acid aptamers category is expected to lead with a significant global market share in 2023 because it’s very stable, easy to change, and cheap to make. Its demand is further driven by its adaptability in numerous applications, such as pharmaceuticals, biosensors, and diagnostics. Further, DNA aptamers are becoming more popular as a result of rising investment in R&D and improvements in DNA synthesis technologies, which is growing the worldwide market.
The biopharmaceutical companies segment is predicted to grow rapidly in the nucleic acid aptamers market because there is a growing need for novel diagnostic and therapeutic solutions and a growing investment in R&D. Aptamers are appealing for drug discovery and development due to their many advantages, including high specificity, stability, and cost-effectiveness. Nucleic acid aptamers are in high demand in this market because of the increasing fascination with targeted therapeutics and customized medicine, which is growing the biopharmaceutical companies segment growth.
The North American nucleic acid aptamers market is expected to report the highest market revenue share in the near future because of the growing popularity of cutting-edge diagnostic and treatment options, improved healthcare infrastructure, and substantial funding for biotechnology research. The market is also being propelled even higher by a strong pharmaceutical industry and government programs that are encouraging. In addition, the Asia-Pacific region is expected to grow quickly in the global nucleic acid aptamers market because due to the increasing need for cutting-edge diagnostic and therapeutic solutions, the expansion of biotechnology research, and the expansion of healthcare infrastructure investments, which is growing the market demand in this area.
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Report Attribute |
Specifications |
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Market Size Value In 2023 |
USD 217.3 Mn |
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Revenue Forecast In 2031 |
USD 732.5 Mn |
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Growth Rate CAGR |
CAGR of 16.7% from 2024 to 2031 |
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Quantitative Units |
Representation of revenue in US$ Mn and CAGR from 2024 to 2031 |
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Historic Year |
2019 to 2023 |
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Forecast Year |
2024-2031 |
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Report Coverage |
The forecast of revenue, the position of the company, the competitive market structure, growth prospects, and trends |
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Segments Covered |
By Type, Application, Indication and End-User |
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Regional Scope |
North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
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Country Scope |
U.S.; Canada; U.K.; Germany; China; India; Japan; Brazil; Mexico; France; Italy; Spain; South East Asia; South Korea |
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Competitive Landscape |
Aptagen Labs, Aptamer Group, Base Pair Biotechnologies, NeoVentures Biotechnology Inc., Aptamer Sciences, Inc., SomaLogic Operating Co., Inc., AptaTargets SL., and Aptus Biotech S.L. |
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Customization Scope |
Free customization report with the procurement of the report and modifications to the regional and segment scope. Particular Geographic competitive landscape. |
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Pricing And Available Payment Methods |
Explore pricing alternatives that are customized to your particular study requirements. |
Chapter 1. Methodology and Scope
1.1. Research Methodology
1.2. Research Scope & Assumptions
Chapter 2. Executive Summary
Chapter 3. Global Nucleic Acid Aptamers Market Snapshot
Chapter 4. Global Nucleic Acid Aptamers Market Variables, Trends & Scope
4.1. Market Segmentation & Scope
4.2. Drivers
4.3. Challenges
4.4. Trends
4.5. Investment and Funding Analysis
4.6. Industry Analysis – Porter’s Five Forces Analysis
4.7. Competitive Landscape & Market Share Analysis
4.8. Impact of Covid-19 Analysis
Chapter 5. Market Segmentation 1: By Type Estimates & Trend Analysis
5.1. By Type & Market Share, 2023 & 2031
5.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following By Type:
5.2.1. DNA Aptamer
5.2.2. RNA Aptamer
5.2.3. XNA Aptamer
Chapter 6. Market Segmentation 2: By Application Estimates & Trend Analysis
6.1. By Application & Market Share, 2023 & 2031
6.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following By Application:
6.2.1. Drug Delivery
6.2.2. Anti-viral Therapy
6.2.3. Pathogen Recognition
6.2.4. Disease Recognition
6.2.5. Stem Cell Markers
6.2.6. Others
Chapter 7. Market Segmentation 3: By Indication Estimates & Trend Analysis
7.1. By Indication & Market Share, 2023 & 2031
7.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following By Indication:
7.2.1. Viral Infection
7.2.2. Cancer
7.2.3. Ophthalmology
7.2.4. Others
Chapter 8. Market Segmentation 4: by End User Estimates & Trend Analysis
8.1. by End User & Market Share, 2023 & 2031
8.2. Market Size (Value (US$ Mn)) & Forecasts and Trend Analyses, 2019 to 2031 for the following by End User:
8.2.1. Biopharmaceutical Companies
8.2.2. Diagnostic Centers
8.2.3. CROs
8.2.4. Others
Chapter 9. Nucleic Acid Aptamers Market Segmentation 5: Regional Estimates & Trend Analysis
9.1. North America
9.1.1. North America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Type, 2024-2031
9.1.2. North America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by End User, 2024-2031
9.1.3. North America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
9.1.4. North America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Indication, 2024-2031
9.1.5. North America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031
9.2. Europe
9.2.1. Europe Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Type, 2024-2031
9.2.2. Europe Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by End User, 2024-2031
9.2.3. Europe Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
9.2.4. Europe Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Indication, 2024-2031
9.2.5. Europe Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031
9.3. Asia Pacific
9.3.1. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Type, 2024-2031
9.3.2. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by End User, 2024-2031
9.3.3. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
9.3.4. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Indication, 2024-2031
9.3.5. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031
9.4. Latin America
9.4.1. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Type, 2024-2031
9.4.2. Asia Pacific Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by End User, 2024-2031
9.4.3. Latin America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
9.4.4. Latin America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Indication, 2024-2031
9.4.5. Latin America Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031
9.5. Middle East & Africa
9.5.1. Middle East & Africa Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Type, 2024-2031
9.5.2. Middle East & Africa Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by End User, 2024-2031
9.5.3. Middle East & Africa Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Application, 2024-2031
9.5.4. Middle East & Africa Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by Indication, 2024-2031
9.5.5. Middle East & Africa Nucleic Acid Aptamers Market Revenue (US$ Million) Estimates and Forecasts by country, 2024-2031
Chapter 10. Competitive Landscape
10.1. Major Mergers and Acquisitions/Strategic Alliances
10.2. Company Profiles
10.2.1. Aptagen Labs
10.2.2. Aptamer Group
10.2.3. Base Pair Biotechnologies
10.2.4. NeoVentures Biotechnology Inc.
10.2.5. Aptamer Sciences, Inc.
10.2.6. SomaLogic Operating Co., Inc.
10.2.7. AptaTargets SL.
10.2.8. Aptus Biotech S.L.
10.2.9. Other Prominent Players
Nucleic Acid Aptamers Market By Type-
Nucleic Acid Aptamers Market By Applications-
Nucleic Acid Aptamers Market By Indication-
Nucleic Acid Aptamers Market By End-User-
Nucleic Acid Aptamers Market By Region-
North America-
Europe-
Asia-Pacific-
Latin America-
Middle East & Africa-
InsightAce Analytic follows a standard and comprehensive market research methodology focused on offering the most accurate and precise market insights. The methods followed for all our market research studies include three significant steps – primary research, secondary research, and data modeling and analysis - to derive the current market size and forecast it over the forecast period. In this study, these three steps were used iteratively to generate valid data points (minimum deviation), which were cross-validated through multiple approaches mentioned below in the data modeling section.
Through secondary research methods, information on the market under study, its peer, and the parent market was collected. This information was then entered into data models. The resulted data points and insights were then validated by primary participants.
Based on additional insights from these primary participants, more directional efforts were put into doing secondary research and optimize data models. This process was repeated till all data models used in the study produced similar results (with minimum deviation). This way, this iterative process was able to generate the most accurate market numbers and qualitative insights.
Secondary research
The secondary research sources that are typically mentioned to include, but are not limited to:
The paid sources for secondary research like Factiva, OneSource, Hoovers, and Statista
Primary Research:
Primary research involves telephonic interviews, e-mail interactions, as well as face-to-face interviews for each market, category, segment, and subsegment across geographies
The contributors who typically take part in such a course include, but are not limited to:
Data Modeling and Analysis:
In the iterative process (mentioned above), data models received inputs from primary as well as secondary sources. But analysts working on these models were the key. They used their extensive knowledge and experience about industry and topic to make changes and fine-tuning these models as per the product/service under study.
The standard data models used while studying this market were the top-down and bottom-up approaches and the company shares analysis model. However, other methods were also used along with these – which were specific to the industry and product/service under study.
